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TKT dimer [cytosol]
Stable Identifier
R-HSA-71322
Type
Complex
Species
Homo sapiens
Compartment
cytosol
Synonyms
transketolase dimer
Locations in the PathwayBrowser
Expand all
Cellular responses to stimuli (Homo sapiens)
Cellular responses to stress (Homo sapiens)
Cellular response to chemical stress (Homo sapiens)
KEAP1-NFE2L2 pathway (Homo sapiens)
Nuclear events mediated by NFE2L2 (Homo sapiens)
NFE2L2 regulates pentose phosphate pathway genes (Homo sapiens)
NFE2L2-dependent TKT gene expression (Homo sapiens)
TKT dimer [cytosol] (Homo sapiens)
Metabolism (Homo sapiens)
Integration of energy metabolism (Homo sapiens)
Insulin effects increased synthesis of Xylulose-5-Phosphate (Homo sapiens)
D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate <=> xylulose 5-phosphate + D-erythrose 4-phosphate (Homo sapiens)
TKT dimer [cytosol] (Homo sapiens)
D-glyceraldehyde 3-phosphate + sedoheptulose 7-phosphate<=> xylulose 5-phosphate+ribose 5-phosphate (Homo sapiens)
TKT dimer [cytosol] (Homo sapiens)
Metabolism of carbohydrates (Homo sapiens)
Pentose phosphate pathway (Homo sapiens)
D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate <=> xylulose 5-phosphate + D-erythrose 4-phosphate (Homo sapiens)
TKT dimer [cytosol] (Homo sapiens)
D-glyceraldehyde 3-phosphate + sedoheptulose 7-phosphate<=> xylulose 5-phosphate+ribose 5-phosphate (Homo sapiens)
TKT dimer [cytosol] (Homo sapiens)
ribose 5-phosphate + xylulose 5-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate (Homo sapiens)
TKT dimer [cytosol] (Homo sapiens)
xylulose 5-phosphate + D-erythrose 4-phosphate <=> D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate (Homo sapiens)
TKT dimer [cytosol] (Homo sapiens)
Literature References
PubMed ID
Title
Journal
Year
9357955
Aspartate 155 of human transketolase is essential for thiamine diphosphate-magnesium binding, and cofactor binding is required for dimer formation
Singleton, CK
,
Wang, JJ
,
Martin, PR
Biochim Biophys Acta
1997
Participants
components
x 2
Mg2+ [cytosol]
x 2
ThDP [cytosol]
x 2
TKT [cytosol]
(Homo sapiens)
Participates
as an output of
NFE2L2-dependent TKT gene expression (Homo sapiens)
Inferred To
TKT dimer [cytosol]
(Bos taurus)
TKT dimer [cytosol]
(Caenorhabditis elegans)
TKT dimer [cytosol]
(Canis familiaris)
TKT dimer [cytosol]
(Drosophila melanogaster)
TKT dimer [cytosol]
(Gallus gallus)
TKT dimer [cytosol]
(Mus musculus)
TKT dimer [cytosol]
(Rattus norvegicus)
TKT dimer [cytosol]
(Sus scrofa)
TKT dimer [cytosol]
(Xenopus tropicalis)
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