While initial studies of PGYM from rabbit muscle suggested that it is a homotetramer (Keller and Cori 1953), more recent work indicates that under physiological conditions the enzyme occurs as a homodimer (Huang and Graves 1970) and a dimeric structure for the human enzyme is inferred here.
Cori, GT, Keller, PJ
Walsh, DA, Brushia, RJ
Huang, CY, Graves, DJ
Vorgerd, M, Kilimann, MW, Moses, SW, Schroers, A, Clemens, PR, Shin, YS, Burwinkel, B, Pongratz, D, Hu, B
phosphorylase kinase activity of phosphorylase kinase complex (PHKM) [cytosol]
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