acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic]

Stable Identifier
R-HSA-71691
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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ALDH1A1 (aldehyde dehydrogenase) in the cytosol catalyzes the reaction of acetaldehyde and NAD+ to form acetate and NADH + H+ (Inoue et al. 1979). The active form of the enzyme is a tetramer (Ni et al. 1999).

Literature References
PubMed ID Title Journal Year
224930 Purification and partial characterization of aldehyde dehydrogenase from human erythrocytes.

Inoue, K, Nishimukai, H, Yamasawa, K

Biochim Biophys Acta 1979
10631996 Human liver mitochondrial aldehyde dehydrogenase: three-dimensional structure and the restoration of solubility and activity of chimeric forms

Ni, L, Zhou, J, Hurley, TD, Weiner, H

Protein Sci 1999
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
aldehyde dehydrogenase (NAD) activity of ALDH1A1 tetramer [cytosol]
Physical Entity
Activity
Orthologous Events
Authored
Reviewed