acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic]

Stable Identifier
R-HSA-71735
Type
Reaction [transition]
Species
Homo sapiens
Compartment
ReviewStatus
5/5
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Cytosolic ACSS2 (acetyl-coenzyme A synthetase) catalyzes the reaction of acetate, coenzyme A, and ATP to form acetyl-CoA, AMP, and pyrophosphate (Luong et al. 2000).
Literature References
PubMed ID Title Journal Year
10843999 Molecular characterization of human acetyl-CoA synthetase, an enzyme regulated by sterol regulatory element-binding proteins.

Goldstein, JL, Luong, A, Hannah, VC

J Biol Chem 2000
Participants
Participates
Catalyst Activity

acetate-CoA ligase activity of ACSS2 [cytosol]

Orthologous Events
Cross References
Rhea
Authored
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