Reactome | TXNL4A [nucleoplasm]

TXNL4A [nucleoplasm]

Stable Identifier

R-HSA-71875

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

DIM1, DIM1_HUMAN, Spliceosomal U5 snRNP-specific 15 kDa protein, DIM1 protein homolog, Thioredoxin-like U5 snRNP protein U5-15kD

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:P83876 TXNL4A

Gene Names

TXNL4A, DIM1, TXNL4

Chain

chain:1-142

Reference Genes

BioGPS Gene:10907 TXNL4A

COSMIC (genes):TXNL4A TXNL4A

CTD Gene:10907 TXNL4A

dbSNP Gene:10907 TXNL4A

ENSEMBL:ENSG00000141759 TXNL4A

HGNC:30551 TXNL4A

KEGG:hsa:10907 TXNL4A

Monarch:10907 TXNL4A

NCBI Gene:10907 TXNL4A

OMIM:611595 TXNL4A

UCSC:P83876 TXNL4A

Reference Transcript

Other Identifiers

10907

11734679_a_at

11756404_a_at

1555461_PM_at

1555461_at

16856153

202835_PM_at

202835_at

202836_PM_s_at

202836_s_at

33631_at

33632_g_at

3814736

3814737

3814738

3814739

3814743

3814744

3814745

3814746

3814747

3814751

3814753

3814754

3814763

3814764

57021_at

8023920

A_23_P130304

A_24_P108281

A_24_P116871

GE54184

GO:0000245

GO:0000375

GO:0000398

GO:0005515

GO:0005634

GO:0005654

GO:0005681

GO:0005682

GO:0005737

GO:0005829

GO:0006397

GO:0008380

GO:0016071

GO:0043226

GO:0046540

GO:0051301

GO:0065003

GO:0071005

HMNXSV003000363

HMNXSV003002779

HMNXSV003013886

Hs2Affx.1.315.S1_3p_at

ILMN_1790218

PH_hs_0020026

PH_hs_0035965

TC18000592.hg

g12654440_3p_at

g5729801_3p_a_at

Participates

as an output of

Formation of the Spliceosomal Bact complex (Homo sapiens)

as a component of

Inferred To

Dim1 [nucleoplasm] (Drosophila melanogaster)

dib-1 [nucleoplasm] (Caenorhabditis elegans)

dim1 [nucleoplasm] (Schizosaccharomyces pombe)

Ghost homologue of TXNL4A [nucleoplasm] (Rattus norvegicus)

txnl4a [nucleoplasm] (Dictyostelium discoideum)

txnl4a [nucleoplasm] (Xenopus tropicalis)

Txnl4a [nucleoplasm] (Mus musculus)

TXNL4A [nucleoplasm] (Bos taurus)

TXNL4A [nucleoplasm] (Canis familiaris)

TXNL4A [nucleoplasm] (Gallus gallus)

TXNL4A [nucleoplasm] (Plasmodium falciparum)

TXNL4A [nucleoplasm] (Sus scrofa)

Cross References

RefSeq

NP_001292493.1, NP_001292492.1, NP_001292486.1, NP_006692.1, NP_001290400.1

OpenTargets

ENSG00000141759

ENSEMBL

ENST00000269601, ENSP00000269601

HPA

ENSG00000141759-TXNL4A

PRO

P83876

Pharos - Targets

P83876

Orphanet

TXNL4A

GlyGen

P83876

PDB

8QO9, 8R0A, 8R09, 8RM5, 4BWS, 8R08, 4BWQ, 3JCR, 6AH0, 8H6K, 1QGV, 8H6L, 8H6J, 8R0B, 1SYX, 6QW6, 8QPK, 8QPE, 4CDO, 1PQN, 8H6E, 6QX9, 8QP9, 8QP8, 5O9Z, 8QZS, 6AHD, 8QPB, 8QXD, 8Q7N, 8QOZ, 8QPA

Interactors (13)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:O95400 CD2BP2	1	CD2BP2 [nucleoplasm] (R-HSA-72054)	0.789	6
UniProt:O94906 PRPF6	1	PRPF6 [nucleoplasm] (R-HSA-71881)	0.728	6
UniProt:P62306 SNRPF	2	SNRPF [cytosol] (R-HSA-191852) SNRPF [nucleoplasm] (R-HSA-71907)	0.643	4
UniProt:Q96DI7 SNRNP40	1	SNRNP40 [nucleoplasm] (R-HSA-71877)	0.643	4
UniProt:O00471 EXOC5	2	EXOC5 [cytosol] (R-HSA-265045) EXOC5 [cytosol] (R-HSA-5623383)	0.556	3
UniProt:Q9BRK4 LZTS2			0.556	3
UniProt:Q96D03 DDT4L			0.556	3
UniProt:Q8TAI7 REBL1			0.553	2
UniProt:P14678 SNRPB	4	2xMe-SNRPB [cytosol] (R-HSA-192218) SNRPB [cytosol] (R-HSA-191798) Me2-R108,R112-SNRPB [nucleoplasm] (R-HSA-192213) SNRPB [nucleoplasm] (R-HSA-71896)	0.527	2
UniProt:Q9BUQ8 DDX23	1	DDX23 [nucleoplasm] (R-HSA-71879)	0.527	3
UniProt:Q15029 EFTUD2	1	EFTUD2 [nucleoplasm] (R-HSA-71883)	0.527	2
UniProt:Q6P2Q9 PRPF8	1	PRPF8 [nucleoplasm] (R-HSA-83810)	0.527	2
UniProt:P63162 SNRPN	1	Me2-R108,R112-SNRPN [nucleoplasm] (R-HSA-8865931)	0.527	3