Reactome | TXNL4A [nucleoplasm]

TXNL4A [nucleoplasm]

Stable Identifier

R-HSA-71875

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

DIM1, DIM1_HUMAN, Spliceosomal U5 snRNP-specific 15 kDa protein, DIM1 protein homolog, Thioredoxin-like U5 snRNP protein U5-15kD

Locations in the PathwayBrowser for interactor UniProt:Q15029 EFTUD2

Expand all

External Reference Information

External Reference

UniProt:P83876 TXNL4A

Gene Names

TXNL4A, DIM1, TXNL4

Chain

chain:1-142

Reference Genes

BioGPS Gene:10907 TXNL4A

COSMIC (genes):TXNL4A TXNL4A

CTD Gene:10907 TXNL4A

dbSNP Gene:10907 TXNL4A

ENSEMBL:ENSG00000141759 TXNL4A

ENSEMBL_homo_sapiens_GENE:ENSG00000141759.15 TXNL4A

HGNC:30551 TXNL4A

KEGG Gene (Homo sapiens):10907 TXNL4A

Monarch:10907 TXNL4A

NCBI Gene:10907 TXNL4A

OMIM:611595 TXNL4A

UCSC:P83876 TXNL4A

Reference Transcript

Other Identifiers

10907

11734679_a_at

11756404_a_at

1555461_PM_at

1555461_at

16856153

202835_PM_at

202835_at

202836_PM_s_at

202836_s_at

33632_g_at

3814736

3814737

3814738

3814739

3814744

3814745

3814753

3814754

57021_at

8023920

A_23_P130304

A_24_P108281

A_24_P116871

GE54184

GO:0000245

GO:0000375

GO:0000398

GO:0005515

GO:0005634

GO:0005654

GO:0005681

GO:0005682

GO:0005829

GO:0006397

GO:0007049

GO:0008380

GO:0016071

GO:0043226

GO:0046540

GO:0051301

GO:0065003

GO:0071005

HMNXSV003000363

HMNXSV003002779

HMNXSV003013886

Hs2Affx.1.315.S1_3p_at

ILMN_1790218

PH_hs_0020026

PH_hs_0035965

g12654440_3p_at

g5729801_3p_a_at

Participates

as an output of

Formation of the Spliceosomal Bact complex (Homo sapiens)

as a component of

Inferred To

Dim1 [nucleoplasm] (Drosophila melanogaster)

dib-1 [nucleoplasm] (Caenorhabditis elegans)

dim1 [nucleoplasm] (Schizosaccharomyces pombe)

Ghost homologue of TXNL4A [nucleoplasm] (Rattus norvegicus)

txnl4a [nucleoplasm] (Dictyostelium discoideum)

txnl4a [nucleoplasm] (Xenopus tropicalis)

Txnl4a [nucleoplasm] (Mus musculus)

TXNL4A [nucleoplasm] (Bos taurus)

TXNL4A [nucleoplasm] (Canis familiaris)

TXNL4A [nucleoplasm] (Gallus gallus)

TXNL4A [nucleoplasm] (Plasmodium falciparum)

TXNL4A [nucleoplasm] (Sus scrofa)

Cross References

RefSeq

NP_001292486.1, NP_001292493.1, NP_006692.1, NP_001290400.1, NP_001292492.1

OpenTargets

ENSG00000141759

GeneCards

P83876

HPA

ENSG00000141759-TXNL4A

Ensembl

ENST00000269601, ENSP00000269601, ENSG00000141759

PRO

P83876

Pharos - Targets

P83876

Orphanet

23092

PDB

1SYX, 1QGV, 3JCR, 6QW6, 1PQN, 8QO9, 4CDO, 4BWQ, 8Q7N, 5O9Z, 6AH0, 4BWS, 6AHD, 6QX9

Interactors (13)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:O95400 CD2BP2	1	CD2BP2 [nucleoplasm] (R-HSA-72054)	0.789	6
UniProt:O94906 PRPF6	1	PRPF6 [nucleoplasm] (R-HSA-71881)	0.728	6
UniProt:Q96DI7 SNRNP40	1	SNRNP40 [nucleoplasm] (R-HSA-71877)	0.643	4
UniProt:P62306 SNRPF	2	SNRPF [nucleoplasm] (R-HSA-71907) SNRPF [cytosol] (R-HSA-191852)	0.643	4
UniProt:Q96D03 DDT4L			0.556	3
UniProt:Q9BRK4 LZTS2			0.556	3
UniProt:O00471 EXOC5	2	EXOC5 [cytosol] (R-HSA-265045) EXOC5 [cytosol] (R-HSA-5623383)	0.556	3
UniProt:Q8TAI7 REBL1			0.553	2
UniProt:P63162 SNRPN	1	Me2-R108,R112-SNRPN [nucleoplasm] (R-HSA-8865931)	0.527	3
UniProt:Q6P2Q9 PRPF8	1	PRPF8 [nucleoplasm] (R-HSA-83810)	0.527	2
UniProt:Q15029 EFTUD2	1	EFTUD2 [nucleoplasm] (R-HSA-71883)	0.527	2
UniProt:P14678 SNRPB	4	SNRPB [nucleoplasm] (R-HSA-71896) Me2-R108,R112-SNRPB [nucleoplasm] (R-HSA-192213) SNRPB [cytosol] (R-HSA-191798) 2xMe-SNRPB [cytosol] (R-HSA-192218)	0.527	2
UniProt:Q9BUQ8 DDX23	1	DDX23 [nucleoplasm] (R-HSA-71879)	0.527	3

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