Reactome | PCBP1 [nucleoplasm]

PCBP1 [nucleoplasm]

Stable Identifier

R-HSA-71919

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

hnRNP-E1, PCB1_HUMAN, Poly(rC)-binding protein 1, Alpha-CP1, Nucleic acid binding protein SUB2.3

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q15365 PCBP1

Gene Names

PCBP1

Chain

chain:1-356

Reference Genes

BioGPS Gene:5093 PCBP1

COSMIC (genes):PCBP1 PCBP1

CTD Gene:5093 PCBP1

dbSNP Gene:5093 PCBP1

ENSEMBL:ENSG00000169564 PCBP1

HGNC:8647 PCBP1

KEGG Gene (Homo sapiens):5093 PCBP1

Monarch:5093 PCBP1

NCBI Gene:5093 PCBP1

OMIM:601209 PCBP1

Reference Transcript

RefSeq:NM_006196.3 PCBP1

Other Identifiers

0000730047

11758107_x_at

16881153

208620_at

2487640

2487641

2487642

2487643

2487644

2487645

2487646

3416066

34305_at

5093

8042515

A_14_P103385

A_23_P68040

A_24_P103025

GE81608

GO:0000398

GO:0000981

GO:0003674

GO:0003676

GO:0003677

GO:0003697

GO:0003700

GO:0003723

GO:0003729

GO:0005515

GO:0005575

GO:0005576

GO:0005615

GO:0005622

GO:0005634

GO:0005654

GO:0005737

GO:0005829

GO:0006397

GO:0008150

GO:0009058

GO:0016020

GO:0016070

GO:0016607

GO:0034641

GO:0036464

GO:0039694

GO:0043226

GO:0044403

GO:0045296

GO:0045944

GO:0070062

GO:0098847

ILMN_1673215

PH_hs_0028716

PH_hs_0030894

TC02000414.hg

Z29505_at

g1215670_3p_at

Participant Of

input

Formation of pre-mRNPs

hasComponent

output

Cleavage at the 3'-Splice Site and Exon Ligation

Inferred To

Ghost homologue of PCBP1 [nucleoplasm] (Rattus norvegicus)

PCBP1 [nucleoplasm] (Bos taurus)

PCBP1 [nucleoplasm] (Canis familiaris)

PCBP1 [nucleoplasm] (Dictyostelium discoideum)

PCBP1 [nucleoplasm] (Sus scrofa)

Pcbp1 [nucleoplasm] (Mus musculus)

LOC426023 [nucleoplasm] (Gallus gallus)

pcbp2 [nucleoplasm] (Danio rerio)

pes-4 [nucleoplasm] (Caenorhabditis elegans)

pcbp3 [nucleoplasm] (Xenopus tropicalis)

mub [nucleoplasm] (Drosophila melanogaster)

Cross References

RefSeq

NP_006187.2

OpenTargets

ENSG00000169564

GeneCards

Q15365

HPA

ENSG00000169564-PCBP1

Ensembl

ENSG00000169564, ENST00000303577, ENSP00000305556

PRO

Q15365

PDB

3VKE, 1WVN, 1ZTG

Interactors (26)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P09012 SNRPA	1	SNRPA [nucleoplasm] (R-HSA-71915)	0.781	9
UniProt:Q13153-1 PAK1			0.602	5
UniProt:O41951 O41951			0.602	4
UniProt:Q6ZRY4 RBPS2			0.601	4
UniProt:O43251-10 RBFOX2			0.556	3
UniProt:Q08117-2 TLE5			0.556	3
UniProt:Q96EK4 THA11			0.556	4
UniProt:O00425 IGF2BP3	1	IGF2BP3 [cytosol] (R-HSA-428313)	0.556	3
UniProt:Q13351 KLF1			0.556	3
UniProt:P98179 RBM3			0.556	3
UniProt:A0A024R5S0 A0A024R5S0			0.556	3
UniProt:P11940 PABPC1	1	PABPC1 [cytosol] (R-HSA-156803)	0.527	2
UniProt:Q12771 Q12771			0.527	2
UniProt:Q13153 PAK1	6	p-S144-PAK1 [cytosol] (R-HSA-451339) Active PAK1 [cytosol] (R-HSA-8964622) PAK1 [plasma membrane] (R-HSA-3928409) p-S144,T423-PAK1 [plasma membrane] (R-HSA-3928472) PAK1 [cytosol] (R-HSA-162629) p-S144,T423-PAK1 [cytosol] (R-HSA-399819)	0.524	2
UniProt:Q67020 Q67020			0.508	2
UniProt:Q15366 PCBP2	2	PCBP2 [nucleoplasm] (R-HSA-71921) PCBP2 [cytosol] (R-HSA-983457)	0.508	2
UniProt:Q13427 PPIG			0.508	2
UniProt:P26599 PTBP1	1	PTBP1 [nucleoplasm] (R-HSA-71923)	0.508	2
UniProt:Q9UHX1 PUF60	1	PUF60 [nucleoplasm] (R-HSA-8865910)	0.508	2
UniProt:Q96PU8 QKI	2	QKI-RAF1 fusion [cytosol] (R-HSA-6802466) p-QKI-BRAF fusion [cytosol] (R-HSA-6802546)	0.508	2
UniProt:Q9Y2W2 WBP11	1	WBP11 [nucleoplasm] (R-HSA-8867887)	0.508	2
UniProt:Q6P2Q9 PRPF8	1	PRPF8 [nucleoplasm] (R-HSA-83810)	0.508	2
UniProt:Q96NB3 ZNF830	1	ZNF830 [nucleoplasm] (R-HSA-6781962)	0.508	2
UniProt:Q9Y3Q8 T22D4			0.508	2
UniProt:P03120 VE2			0.488	2
UniProt:Q2Q067 Q2Q067			0.488	2

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