Reactome | CSTF1 [nucleoplasm]

CSTF1 [nucleoplasm]

Stable Identifier

R-HSA-72001

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

CSTF 50 kDa subunit, CST1_HUMAN, Cleavage stimulation factor, 50 kDa subunit, CF-1 50 kDa subunit

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q05048 CSTF1

Gene Names

CSTF1

Chain

chain:1-431

Reference Genes

BioGPS Gene:1477 CSTF1

COSMIC (genes):CSTF1 CSTF1

CTD Gene:1477 CSTF1

dbSNP Gene:1477 CSTF1

ENSEMBL:ENSG00000101138 CSTF1

ENSEMBL:ENSG00000101138.12 CSTF1

HGNC:2483 CSTF1

KEGG Gene (Homo sapiens):1477 CSTF1

Monarch:1477 CSTF1

NCBI Gene:1477 CSTF1

OMIM:600369 CSTF1

UCSC:Q05048 CSTF1

Reference Transcript

Other Identifiers

11739099_a_at

11739100_a_at

11741029_x_at

11758689_s_at

1477

16915015

202190_PM_at

202190_at

32723_PM_at

32723_at

3890157

3890158

3890162

3890163

3890166

3890167

3890168

3890170

3890171

3890172

3890173

3890174

3890175

3890176

3890178

3890179

4865642_3p_at

8063484

A_23_P362824

GE57546

GO:0003723

GO:0005515

GO:0005634

GO:0005654

GO:0005848

GO:0006397

GO:0016071

GO:0031124

GO:0043226

HMNXSV003022140

ILMN_1682198

ILMN_1735185

L02547_at

PH_hs_0010353

TC20000428.hg

g4557490_3p_at

g4557490_3p_s_at

Participates

as a component of

CstF [nucleoplasm] (Homo sapiens)

Inferred To

fc22d10 [nucleoplasm] (Danio rerio)

Ghost homologue of CSTF1 [nucleoplasm] (Saccharomyces cerevisiae)

Ghost homologue of CSTF1 [nucleoplasm] (Schizosaccharomyces pombe)

Ghost homologue of CSTF1 [nucleoplasm] (Xenopus tropicalis)

CSTF1 [nucleoplasm] (Bos taurus)

CSTF1 [nucleoplasm] (Canis familiaris)

CSTF1 [nucleoplasm] (Gallus gallus)

CSTF1 [nucleoplasm] (Sus scrofa)

cstf1 [nucleoplasm] (Dictyostelium discoideum)

CstF50 [nucleoplasm] (Drosophila melanogaster)

Cstf1 [nucleoplasm] (Mus musculus)

Cstf1 [nucleoplasm] (Rattus norvegicus)

cpf-1 [nucleoplasm] (Caenorhabditis elegans)

Cross References

RefSeq

NP_001028694.1, NP_001315.1, NP_001028693.1, XP_011526902.1

OpenTargets

ENSG00000101138

GeneCards

Q05048

HPA

ENSG00000101138-CSTF1

Ensembl

ENST00000217109, ENSP00000217109, ENSG00000101138

PRO

Q05048

Pharos - Targets

Q05048

PDB

6B3X

Interactors (2)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q99728 BARD1	13	BARD1 G623E [nucleoplasm] (R-HSA-9699135) BARD1 C71Y [nucleoplasm] (R-HSA-9700808) BARD1 C53W [nucleoplasm] (R-HSA-9700807) BARD1 G623W [nucleoplasm] (R-HSA-9699148) BARD1 W34R [nucleoplasm] (R-HSA-9699166) BARD1 H68Y [nucleoplasm] (R-HSA-9699151) BARD1 L44R [nucleoplasm] (R-HSA-9699126) BARD1 C50G [nucleoplasm] (R-HSA-9699137) BARD1 C83G [nucleoplasm] (R-HSA-9699139) K6PolyUb,p-T714,T734-BARD1 [nucleoplasm] (R-HSA-9707286) p-T714,T734-BARD1 [nucleoplasm] (R-HSA-5659846) K6PolyUb-BARD1 [nucleoplasm] (R-HSA-9701024) BARD1 [nucleoplasm] (R-HSA-5659775)	0.581	4
UniProt:Q9H0E2 TOLLIP	4	TOLLIP [cytosol] (R-HSA-446885) TOLLIP [azurophil granule lumen] (R-HSA-6799709) TOLLIP [extracellular region] (R-HSA-6800448) TOLLIP [specific granule lumen] (R-HSA-6799719)	0.499	2