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SRSF6 [nucleoplasm]
Stable Identifier
R-HSA-72026
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
SRp55, Splicing factor, arginine/serine-rich 6 (Pre-mRNA splicing factor SRP55), Splicing factor, arginine/serine-rich 6, Pre-mRNA splicing factor SRP55
Locations in the PathwayBrowser for interactor UniProt:P84103 SRSF3
Expand all
Metabolism of RNA (Homo sapiens)
Processing of Capped Intron-Containing Pre-mRNA (Homo sapiens)
Transport of Mature Transcript to Cytoplasm (Homo sapiens)
Transport of Mature mRNA derived from an Intron-Containing Transcript (Homo sapiens)
Docking of the TAP:EJC Complex with the NPC (Homo sapiens)
SRSF6 [nucleoplasm] (Homo sapiens)
mRNA Splicing (Homo sapiens)
mRNA Splicing - Minor Pathway (Homo sapiens)
Formation of AT-AC A complex (Homo sapiens)
SRSF6 [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q13247 SRSF6
Gene Names
SRSF6, SFRS6, SRP55
Chain
chain:1-344
Reference Genes
BioGPS Gene:6431 SRSF6
COSMIC (genes):SRSF6 SRSF6
CTD Gene:6431 SRSF6
dbSNP Gene:6431 SRSF6
ENSEMBL:ENSG00000124193 SRSF6
ENSEMBL_homo_sapiens_GENE:ENSG00000124193.16 SRSF6
HGNC:10788 SRSF6
KEGG Gene (Homo sapiens):6431 SRSF6
Monarch:6431 SRSF6
NCBI Gene:6431 SRSF6
OMIM:601944 SRSF6
UCSC:Q13247 SRSF6
Reference Transcript
RefSeq:NM_006275.5 SRSF6
Other Identifiers
11716303_s_at
11745822_x_at
16913856
206108_PM_s_at
206108_s_at
208804_PM_s_at
208804_s_at
35808_at
35809_g_at
3747328
3747330
3747331
3747332
3747336
3747337
3747338
3886051
3886052
3886053
3886057
3886058
3886060
3886062
3886064
3886066
3886067
3886068
3886069
3886070
3886071
3975695
6431
8062695
A_14_P110688
A_14_P202404
A_23_P109017
A_33_P3220530
A_33_P3238455
GE56094
GE81615
GE86757
GE902686
GO:0000380
GO:0000381
GO:0000398
GO:0003676
GO:0003723
GO:0005515
GO:0005634
GO:0005654
GO:0006376
GO:0006397
GO:0008380
GO:0010629
GO:0010837
GO:0012501
GO:0016071
GO:0016607
GO:0030154
GO:0032868
GO:0036002
GO:0042060
GO:0043226
GO:0045617
GO:0048025
GO:0048856
GO:0060501
GO:0061041
GO:0065003
GO:2000675
HMNXSV003041172
Hs.6891.1.A2_3p_a_at
ILMN_1697469
PH_hs_0030938
TC20000316.hg
TC20001227.hg
U30828_at
g11225261_3p_a_at
Participates
as a component of
post exon ligation complex [nucleoplasm] (Homo sapiens)
ATAC C Complex with lariat containing 5'-end cleaved mRNA [nucleoplasm] (Homo sapiens)
ATAC C Complex [nucleoplasm] (Homo sapiens)
ATAC A Complex [nucleoplasm] (Homo sapiens)
Spliceosomal Intermediate C Complex [nucleoplasm] (Homo sapiens)
Spliced mRNP [nucleoplasm] (Homo sapiens)
Spliced mRNA:CBC:EJC:TREX [nucleoplasm] (Homo sapiens)
3' end cleaved, ligated exon containing complex [nucleoplasm] (Homo sapiens)
polyadenylated, capped mRNA:CBC:EJC:TREX:SRSF proteins [nucleoplasm] (Homo sapiens)
capped mRNA:CBC:EJC:TREX (minus DDX39B) [nucleoplasm] (Homo sapiens)
as an input of
Formation of AT-AC A complex (Homo sapiens)
as a member of
shuttling SRSFs [nucleoplasm] (Homo sapiens)
as an output of
Docking of the TAP:EJC Complex with the NPC (Homo sapiens)
Inferred To
rsp-2 [nucleoplasm]
(Caenorhabditis elegans)
Ghost homologue of SRSF6 [nucleoplasm]
(Bos taurus)
Ghost homologue of SRSF6 [nucleoplasm]
(Canis familiaris)
Ghost homologue of SRSF6 [nucleoplasm]
(Danio rerio)
Ghost homologue of SRSF6 [nucleoplasm]
(Dictyostelium discoideum)
Ghost homologue of SRSF6 [nucleoplasm]
(Drosophila melanogaster)
Ghost homologue of SRSF6 [nucleoplasm]
(Gallus gallus)
Ghost homologue of SRSF6 [nucleoplasm]
(Mus musculus)
Ghost homologue of SRSF6 [nucleoplasm]
(Rattus norvegicus)
Ghost homologue of SRSF6 [nucleoplasm]
(Sus scrofa)
Ghost homologue of SRSF6 [nucleoplasm]
(Xenopus tropicalis)
Cross References
RefSeq
NP_006266.2
OpenTargets
ENSG00000124193
GeneCards
Q13247
HPA
ENSG00000124193-SRSF6
Ensembl
ENSG00000124193
,
ENST00000483871
,
ENST00000244020
,
ENSP00000433544
,
ENSP00000244020
PRO
Q13247
Pharos - Targets
Q13247
Interactors (17)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q9Y383 LC7L2
0.781
7
UniProt:Q08170 SRSF4
1
SRSF4 [nucleoplasm]
(R-HSA-72024)
0.667
4
UniProt:P78362 SRPK2
1
SRPK2 [cytosol]
(R-HSA-9729332)
0.643
4
UniProt:Q96SB4 SRPK1
2
SRPK1 [nucleoplasm]
(R-HSA-9821984)
SRPK1 [cytosol]
(R-HSA-9729349)
0.59
3
UniProt:Q9NQ29-3 LUC7L
0.556
3
UniProt:Q15287 RNPS1
2
RNPS1 [nucleoplasm]
(R-HSA-156778)
RNPS1 [cytosol]
(R-HSA-159256)
0.547
3
UniProt:O76021 RL1D1
0.527
3
UniProt:Q86VM9 ZCH18
0.527
6
UniProt:Q53F19 NCBP3
0.527
3
UniProt:Q9NR30 DDX21
1
DDX21 [nucleoplasm]
(R-HSA-5250652)
0.527
2
UniProt:Q14684 RRP1B
0.527
3
UniProt:O60832 DKC1
1
DKC1 [nucleoplasm]
(R-HSA-163102)
0.527
3
UniProt:P05455 SSB
1
SSB [nucleoplasm]
(R-HSA-58418)
0.527
2
UniProt:Q8NAV1 PRPF38A
1
PRPF38A [nucleoplasm]
(R-HSA-8867897)
0.508
2
UniProt:Q13243 SRSF5
1
SRSF5 [nucleoplasm]
(R-HSA-72028)
0.508
3
UniProt:P84103 SRSF3
1
SRSF3 [nucleoplasm]
(R-HSA-72035)
0.508
2
UniProt:O75152 ZC3H11A
1
ZC3H11A [nucleoplasm]
(R-HSA-8850659)
0.483
2
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