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SRSF5 [nucleoplasm]
Stable Identifier
R-HSA-72028
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
SRp40, Splicing factor, arginine/serine-rich 5 (Pre-mRNA splicing factor SRP40) (Delayed-early protein HRS), Splicing factor, arginine/serine-rich 5, Pre-mRNA splicing factor SRP40, Delayed-early protein HRS
Locations in the PathwayBrowser for interactor UniProt:P84103 SRSF3
Expand all
Metabolism of RNA (Homo sapiens)
Processing of Capped Intron-Containing Pre-mRNA (Homo sapiens)
Transport of Mature Transcript to Cytoplasm (Homo sapiens)
Transport of Mature mRNA derived from an Intron-Containing Transcript (Homo sapiens)
Docking of the TAP:EJC Complex with the NPC (Homo sapiens)
SRSF5 [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q13243 SRSF5
Gene Names
SRSF5, HRS, SFRS5, SRP40
Chain
chain:1-272
Reference Genes
BioGPS Gene:6430 SRSF5
COSMIC (genes):SRSF5 SRSF5
CTD Gene:6430 SRSF5
dbSNP Gene:6430 SRSF5
ENSEMBL:ENSG00000100650 SRSF5
HGNC:10787 SRSF5
KEGG:hsa:6430 SRSF5
Monarch:6430 SRSF5
NCBI Gene:6430 SRSF5
OMIM:600914 SRSF5
UCSC:Q13243 SRSF5
Reference Transcript
RefSeq:NM_006925.4 SRSF5
RefSeq:NM_001320214.1 SRSF5
RefSeq:NM_001039465.1 SRSF5
Other Identifiers
11736129_a_at
11736130_x_at
11744492_x_at
11746137_a_at
11747389_a_at
11753802_a_at
11754349_a_at
11756063_x_at
11760242_a_at
11760276_s_at
11760894_s_at
16785869
203380_PM_x_at
203380_x_at
210077_PM_s_at
210077_s_at
212266_PM_s_at
212266_s_at
3542208
3542211
3542212
3542213
3542215
3542216
3542217
3542218
3542219
3542220
3542221
3542222
3542223
3542224
3542225
3542226
3542227
3542228
3542229
3542230
3542231
3542232
3542233
3542234
3542235
3542236
3542237
3542238
3542239
3542240
3542241
3542242
3542243
40453_s_at
6430
7975368
91840_at
A_14_P113391
A_23_P377819
A_33_P3366146
GE59067
GO:0000398
GO:0003676
GO:0003723
GO:0005515
GO:0005634
GO:0005654
GO:0005730
GO:0005829
GO:0006376
GO:0006397
GO:0008380
GO:0016071
GO:0016607
GO:0043226
GO:0065003
HMNXSV003014236
HMNXSV003045563
Hs.166975.3.S1_3p_a_at
ILMN_1761996
ILMN_2378868
PH_hs_0010038
TC14000418.hg
U30827_s_at
g1049089_3p_a_at
g5902077_3p_a_at
Participates
as a component of
Spliceosomal Intermediate C Complex [nucleoplasm] (Homo sapiens)
Spliced mRNP [nucleoplasm] (Homo sapiens)
Spliced mRNA:CBC:EJC:TREX [nucleoplasm] (Homo sapiens)
3' end cleaved, ligated exon containing complex [nucleoplasm] (Homo sapiens)
polyadenylated, capped mRNA:CBC:EJC:TREX:SRSF proteins [nucleoplasm] (Homo sapiens)
capped mRNA:CBC:EJC:TREX (minus DDX39B) [nucleoplasm] (Homo sapiens)
as a member of
nonshuttling SRSFs [nucleoplasm] (Homo sapiens)
as an output of
Docking of the TAP:EJC Complex with the NPC (Homo sapiens)
Inferred To
Srsf5 [nucleoplasm]
(Mus musculus)
Srsf5 [nucleoplasm]
(Rattus norvegicus)
srsf5b [nucleoplasm]
(Danio rerio)
SRSF5 [nucleoplasm]
(Canis familiaris)
SRSF5 [nucleoplasm]
(Gallus gallus)
SRSF5 [nucleoplasm]
(Sus scrofa)
rsp-2 [nucleoplasm]
(Caenorhabditis elegans)
Ghost homologue of SRSF5 [nucleoplasm]
(Dictyostelium discoideum)
Ghost homologue of SRSF5 [nucleoplasm]
(Drosophila melanogaster)
SFRS5 [nucleoplasm]
(Bos taurus)
Cross References
RefSeq
NP_001034554.1
,
NP_001307143.1
,
NP_008856.2
ENSEMBL
ENST00000557154
,
ENSP00000451391
,
ENSP00000377892
,
ENST00000553635
,
ENST00000394366
,
ENSP00000452123
,
ENST00000553521
,
ENSP00000451088
OpenTargets
ENSG00000100650
HPA
ENSG00000100650-SRSF5
PRO
Q13243
Pharos - Targets
Q13243
GlyGen
Q13243
Interactors (7)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P78362 SRPK2
1
SRPK2 [cytosol]
(R-HSA-9729332)
0.688
4
UniProt:Q15696 ZRSR2
1
ZRSR2 [nucleoplasm]
(R-HSA-8865914)
0.556
3
UniProt:Q9H9Z2 LIN28A
1
LIN28A [cytosol]
(R-HSA-500391)
0.527
2
UniProt:Q92731 ESR2
5
ESR2 [cytosol]
(R-HSA-9020970)
ESR2 [nucleoplasm]
(R-HSA-446165)
Me-PalmS-ESR2 [plasma membrane]
(R-HSA-9637787)
PalmS-ESR2 [plasma membrane]
(R-HSA-9021059)
PalmS-ESR2 [cytosol]
(R-HSA-9020979)
0.527
2
UniProt:Q8NAV1 PRPF38A
1
PRPF38A [nucleoplasm]
(R-HSA-8867897)
0.508
2
UniProt:P84103 SRSF3
1
SRSF3 [nucleoplasm]
(R-HSA-72035)
0.508
2
UniProt:Q13247 SRSF6
1
SRSF6 [nucleoplasm]
(R-HSA-72026)
0.508
3
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