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SRSF3 [nucleoplasm]
Stable Identifier
R-HSA-72035
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
SRp20, Splicing factor, arginine/serine-rich 3 (Pre-mRNA splicing factor SRP20) (X16 protein), Splicing factor, arginine/serine-rich 3, Pre-mRNA splicing factor SRP20, X16 protein
Locations in the PathwayBrowser for interactor UniProt:P09429 HMGB1
Expand all
Metabolism of RNA (Homo sapiens)
Processing of Capped Intron-Containing Pre-mRNA (Homo sapiens)
Transport of Mature Transcript to Cytoplasm (Homo sapiens)
Transport of Mature mRNA derived from an Intron-Containing Transcript (Homo sapiens)
Docking of the TAP:EJC Complex with the NPC (Homo sapiens)
SRSF3 [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:P84103 SRSF3
Gene Names
SRSF3, SFRS3, SRP20
Chain
chain:1-164
Reference Genes
BioGPS Gene:6428 SRSF3
COSMIC (genes):SRSF3 SRSF3
CTD Gene:6428 SRSF3
dbSNP Gene:6428 SRSF3
ENSEMBL:ENSG00000112081 SRSF3
ENSEMBL_homo_sapiens_GENE:ENSG00000112081.17 SRSF3
HGNC:10785 SRSF3
KEGG Gene (Homo sapiens):6428 SRSF3
Monarch:6428 SRSF3
NCBI Gene:6428 SRSF3
OMIM:603364 SRSF3
UCSC:P84103 SRSF3
Reference Transcript
RefSeq:NM_003017.4 SRSF3
Other Identifiers
11723038_at
11723039_x_at
11753649_s_at
11753650_x_at
11755128_s_at
11757962_s_at
17007996
202899_PM_s_at
202899_s_at
208672_PM_s_at
208672_s_at
208673_PM_s_at
208673_s_at
235324_PM_at
235324_at
2766463
2905119
2905120
2905122
2905124
2905126
2905127
2905128
2905129
2905130
2905132
2905134
2905136
2905137
2905138
2905139
2905140
2905141
2905142
2905143
3322896
3322900
3322903
351_f_at
40457_at
6428
73345_at
81061_at
8119080
89302_at
A_14_P137284
A_23_P413761
A_33_P3232828
D28423_at
GE752945
GE80149
GE86492
GO:0000398
GO:0003676
GO:0003723
GO:0005515
GO:0005634
GO:0005654
GO:0005737
GO:0006397
GO:0006406
GO:0006913
GO:0008380
GO:0016071
GO:0016607
GO:0031047
GO:0031053
GO:0043226
GO:0043274
GO:0048024
GO:0051028
GO:0060090
GO:0070878
GO:0140517
GO:1990830
HMNXSV003030847
Hs.115315.0.A1_3p_at
ILMN_1723212
ILMN_2135232
L10838_at
PH_hs_0006320
PH_hs_0024643
TC06000530.hg
TC06002757.hg
g12654192_3p_a_at
g4506900_3p_s_at
g5531903_3p_a_at
Participates
as a component of
Spliceosomal Intermediate C Complex [nucleoplasm] (Homo sapiens)
Spliced mRNP [nucleoplasm] (Homo sapiens)
Spliced mRNA:CBC:EJC:TREX [nucleoplasm] (Homo sapiens)
3' end cleaved, ligated exon containing complex [nucleoplasm] (Homo sapiens)
polyadenylated, capped mRNA:CBC:EJC:TREX:SRSF proteins [nucleoplasm] (Homo sapiens)
capped mRNA:CBC:EJC:TREX (minus DDX39B) [nucleoplasm] (Homo sapiens)
as a member of
shuttling SRSFs [nucleoplasm] (Homo sapiens)
as an output of
Docking of the TAP:EJC Complex with the NPC (Homo sapiens)
Inferred To
Homologues of SRSF3 [nucleoplasm]
(Rattus norvegicus)
srsf3a [nucleoplasm]
(Danio rerio)
Rbp1 [nucleoplasm]
(Drosophila melanogaster)
Ghost homologue of SRSF3 [nucleoplasm]
(Dictyostelium discoideum)
Srsf3 [nucleoplasm]
(Mus musculus)
Srsf3 [nucleoplasm]
(Rattus norvegicus)
SRSF3 [nucleoplasm]
(Bos taurus)
SRSF3 [nucleoplasm]
(Caenorhabditis elegans)
SRSF3 [nucleoplasm]
(Canis familiaris)
SRSF3 [nucleoplasm]
(Gallus gallus)
SRSF3 [nucleoplasm]
(Schizosaccharomyces pombe)
SRSF3 [nucleoplasm]
(Sus scrofa)
AABR07026797.1 [nucleoplasm]
(Rattus norvegicus)
Cross References
RefSeq
NP_003008.1
OpenTargets
ENSG00000112081
GeneCards
P84103
HPA
ENSG00000112081-SRSF3
Ensembl
ENST00000373715
,
ENSP00000436036
,
ENST00000620941
,
ENST00000477442
,
ENSP00000482833
,
ENSP00000362820
,
ENSG00000112081
PRO
P84103
Pharos - Targets
P84103
PDB
2I38
,
2I2Y
Interactors (34)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q01081 U2AF1
1
U2AF1 [nucleoplasm]
(R-HSA-71985)
0.73
5
UniProt:P49760 CLK2
0.666
4
UniProt:P49761 CLK3
0.666
4
UniProt:Q8NAV1 PRPF38A
1
PRPF38A [nucleoplasm]
(R-HSA-8867897)
0.641
3
UniProt:P09429 HMGB1
5
HMGB1 [secretory granule lumen]
(R-HSA-6803337)
HMGB1 [ficolin-1-rich granule lumen]
(R-HSA-6803291)
HMGB1 [extracellular region]
(R-HSA-879382)
HMGB1 [nucleoplasm]
(R-HSA-266221)
HC23,45-HMGB1 [extracellular region]
(R-HSA-6797422)
0.613
3
UniProt:P38919 EIF4A3
2
EIF4A3 [nucleoplasm]
(R-HSA-8849149)
EIF4A3 [cytosol]
(R-HSA-927868)
0.597
3
UniProt:P78362 SRPK2
1
SRPK2 [cytosol]
(R-HSA-9729332)
0.59
2
UniProt:Q96SB4 SRPK1
2
SRPK1 [nucleoplasm]
(R-HSA-9821984)
SRPK1 [cytosol]
(R-HSA-9729349)
0.59
2
UniProt:Q15366 PCBP2
2
PCBP2 [nucleoplasm]
(R-HSA-71921)
PCBP2 [cytosol]
(R-HSA-983457)
0.581
3
UniProt:P57721-2 PCBP3
0.556
3
UniProt:Q14011 CIRBP
0.556
3
UniProt:Q15287 RNPS1
2
RNPS1 [nucleoplasm]
(R-HSA-156778)
RNPS1 [cytosol]
(R-HSA-159256)
0.556
3
UniProt:P38159 RBMX
2
RBMX [cytosol]
(R-HSA-9715135)
RBMX [nucleoplasm]
(R-HSA-71939)
0.556
3
UniProt:Q9Y5E9 PCDBE
0.556
3
UniProt:Q8NE01 CNNM3
0.556
3
UniProt:P49759-3 CLK1
0.556
3
UniProt:P32969 RPL9
1
RPL9 [cytosol]
(R-HSA-72492)
0.556
3
UniProt:Q8TBB1 LNX1
1
LNX1 [cytosol]
(R-HSA-8851641)
0.556
3
UniProt:Q8WWY3 PRPF31
1
PRPF31 [nucleoplasm]
(R-HSA-6806772)
0.556
3
UniProt:O00560 SDCBP
3
SDCBP [extracellular region]
(R-HSA-6806206)
SDCBP [azurophil granule lumen]
(R-HSA-6799372)
SDCBP [cytosol]
(R-HSA-373639)
0.556
3
UniProt:P61978-2 HNRNPK
0.556
3
UniProt:P98179 RBM3
0.556
3
UniProt:Q9BRL6-2 SRSF8
0.556
3
UniProt:P26368-2 U2AF2
0.556
3
UniProt:P62995 TRA2B
2
TRA2B [cytosol]
(R-HSA-9715137)
TRA2B [nucleoplasm]
(R-HSA-8850859)
0.547
2
UniProt:Q9UBU9 NXF1
2
NXF1 [cytosol]
(R-HSA-156481)
NXF1 [nucleoplasm]
(R-HSA-111690)
0.544
4
UniProt:Q86VM9 ZCH18
0.527
5
UniProt:Q64368 DAZL
0.527
2
UniProt:P10636-8 MAPT
3
p-S199,S202,S262,S396,S404,S409,T181,T231-MAPT-8 [cytosol]
(R-HSA-9836400)
p-S262,S356,S396-MAPT-8 [cytosol]
(R-HSA-9619521)
MAPT-8 [cytosol]
(R-HSA-9619519)
0.527
4
UniProt:Q53F19 NCBP3
0.527
2
UniProt:Q13243 SRSF5
1
SRSF5 [nucleoplasm]
(R-HSA-72028)
0.508
2
UniProt:Q13247 SRSF6
1
SRSF6 [nucleoplasm]
(R-HSA-72026)
0.508
2
UniProt:Q9JKL7 SREK1
0.499
3
UniProt:P61326 MAGOH
1
MAGOH [nucleoplasm]
(R-HSA-156658)
0.462
2
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