FUS [nucleoplasm]

Stable Identifier
R-HSA-72040
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
FUS - RNA binding protein/TLS, RNA-binding protein FUS, Oncogene FUS, Oncogene TLS, Translocated in liposarcoma protein, POMp75, 75 kDa DNA-pairing protein
Locations in the PathwayBrowser
Expand all
External Reference Information
External Reference
UniProt:P35637 FUS
Gene Names
FUS, TLS
Chain
chain:1-526
Reference Genes
BioGPS Gene:2521 FUS
COSMIC (genes):FUS FUS
CTD Gene:2521 FUS
dbSNP Gene:2521 FUS
ENSEMBL:ENSG00000089280.19 FUS
HGNC:4010 FUS
KEGG Gene (Homo sapiens):2521 FUS
Monarch:2521 FUS
NCBI Gene:2521 FUS
OMIM:137070 FUS
UCSC:P35637 FUS
Reference Transcript
Other Identifiers
0001090348
11745190_a_at
1565717_PM_s_at
1565717_s_at
16818207
200959_3p_at
200959_PM_at
200959_at
217370_3p_x_at
217370_PM_x_at
217370_x_at
2521
3656910
3656912
3656913
3656916
3656917
3656918
3656919
3656920
3656924
3656926
3656928
3656932
3656933
3656936
3656940
3656941
3656942
3656944
3656945
3656946
3656947
39180_at
7995069
A_23_P106887
GE58786
GE85981
GO:0003674
GO:0003676
GO:0003677
GO:0003682
GO:0003712
GO:0003713
GO:0003723
GO:0003729
GO:0003730
GO:0005515
GO:0005575
GO:0005622
GO:0005634
GO:0005654
GO:0005737
GO:0006281
GO:0006310
GO:0006351
GO:0006355
GO:0006357
GO:0008150
GO:0008380
GO:0010467
GO:0016071
GO:0042802
GO:0043167
GO:0043226
GO:0043484
GO:0045893
GO:0046872
GO:0048255
GO:0051260
GO:0065003
GO:1905168
HMNXSV003036649
Hs.99969.2.S1_3p_a_at
Hs.99969.2.S1_3p_s_at
Hs.99969.2.S1_3p_x_at
Hs.99969.3.S1_3p_at
Hs2.392171.1.S1_3p_s_at
ILMN_2306066
PH_hs_0022279
PH_hs_0031515
TC16000372.hg
TC16001494.hg
X71428_at
g4826733_3p_at
g4826733_3p_s_at
g4826733_3p_x_at
Participates
as an input of
as a component of
Inferred To
Dmel\CG14718 [nucleoplasm] (Drosophila melanogaster)
caz [nucleoplasm] (Drosophila melanogaster)
fust-1 [nucleoplasm] (Caenorhabditis elegans)
Fus [nucleoplasm] (Mus musculus)
Fus [nucleoplasm] (Rattus norvegicus)
fus [nucleoplasm] (Xenopus tropicalis)
FUS [nucleoplasm] (Bos taurus)
FUS [nucleoplasm] (Canis familiaris)
FUS [nucleoplasm] (Danio rerio)
FUS [nucleoplasm] (Gallus gallus)
FUS [nucleoplasm] (Sus scrofa)
Homologues of FUS [nucleoplasm] (Drosophila melanogaster)
Cross References
RefSeq
OpenTargets
GeneCards
HPA
Ensembl
PRO
Pharos - Targets
Orphanet
PDB
Interactors (41)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:P35637 FUS  1 0.829 9
 UniProt:Q13148 TADBP      0.683 8
 UniProt:O60739 EIF1B      0.675 4
 UniProt:O75815 BCAR3      0.675 4
 UniProt:O15479 MAGB2      0.675 4
 UniProt:Q8N488 RYBP  1 0.666 4
 UniProt:Q92804 TAF15  1 0.659 7
 UniProt:Q99873 PRMT1  2 0.657 5
 UniProt:P43243 MATR3      0.656 7
 UniProt:Q15424 SAFB  3 0.644 7
 UniProt:P45481 Crebbp  4 0.602 4
 UniProt:Q09472 EP300  5 0.591 4
 UniProt:Q99873-3 PRMT1      0.571 3
 UniProt:Q92973-2 TNPO1      0.558 2
 UniProt:Q8NHS9 SPT22      0.556 3
 UniProt:Q04206-3 RELA      0.556 3
 UniProt:P18206-2 VCL      0.556 3
 UniProt:Q9BYU1 PBX4      0.556 3
 IntAct:EBI-25831191 CCSB      0.556 3
 UniProt:P48730-2 CSNK1D      0.556 3
 UniProt:Q96FW1 OTUB1  2 0.556 3
 UniProt:Q9BUL9 RPP25  1 0.556 3
 UniProt:Q13191 CBLB  1 0.556 3
 UniProt:Q9UKA9-2 PTBP2      0.556 3
 UniProt:P49841-2 GSK3B      0.556 3
 UniProt:P46379-2 BAG6      0.556 3
 UniProt:Q05586 GRIN1  3 0.556 3
 UniProt:P19793 RXRA  4 0.556 3
 UniProt:P60896 SEM1  2 0.556 3
 UniProt:Q01844 EWS      0.547 5
 UniProt:P38159 RBMX  2 0.547 5
 UniProt:P97801  2 0.537 5
 UniProt:Q9NRR4 DROSHA  1 0.524 2
 UniProt:Q92993 KAT5  1 0.524 2
 UniProt:Q9UKM9 RALY      0.518 5
 UniProt:Q15149 PLEC  3 0.518 4
 IntAct:EBI-6932561 FUS      0.512 4
 UniProt:Q08211 DHX9  2 0.512 8
 UniProt:P09651 HNRNPA1  2 0.462 3
 UniProt:P03372 ESR1  8 0.462 2
 UniProt:Q12905 ILF2  4 0.462 7
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