FUS [nucleoplasm]

Stable Identifier
R-HSA-72040
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
FUS - RNA binding protein/TLS, RNA-binding protein FUS, Oncogene FUS, Oncogene TLS, Translocated in liposarcoma protein, POMp75, 75 kDa DNA-pairing protein
Locations in the PathwayBrowser
Expand all
External Reference Information
External Reference
UniProt:P35637 FUS
Gene Names
FUS, TLS
Chain
chain:1-526
Reference Genes
BioGPS Gene:2521 FUS
COSMIC (genes):FUS FUS
CTD Gene:2521 FUS
dbSNP Gene:2521 FUS
ENSEMBL:ENSG00000089280 FUS
HGNC:4010 FUS
KEGG Gene (Homo sapiens):2521 FUS
Monarch:2521 FUS
NCBI Gene:2521 FUS
OMIM:137070 FUS
UCSC:P35637 FUS
Reference Transcript
Other Identifiers
0001090348
11745190_a_at
1564802_3p_at
1564802_at
1565717_s_at
16818207
200959_3p_at
200959_at
217370_3p_x_at
217370_x_at
2521
2LA6
2LCW
33036
3656910
3656912
3656913
3656916
3656917
3656918
3656919
3656920
3656924
3656926
3656928
3656932
3656933
3656936
3656940
3656941
3656942
3656944
3656945
3656946
3656947
3656948
3656949
3656951
3656952
3656953
3656955
3656956
3656958
3656960
39180_at
46825_at
4FDD
4FQ3
58691
5W3N
5XRR
5XSG
5YVG
5YVH
5YVI
6BWZ
6BXV
6BZP
6G99
6GBM
7995069
8784
A_23_P106887
AAB27102
AAB27103
AAC35284
AAC35285
AAH00402
AAH02459
AAP35795
AC009088
AF071213
AJ295163
BC000402
BC002459
BT007131
CAA50558
CAA50559
CAB033036
CAB058691
CAC15058
CAG33028
CCDS10707
CCDS58454
CH471192
CR456747
EAW52150
ENSG00000089280
ENSP00000254108
ENSP00000369594
ENST00000254108
ENST00000254108.11
ENST00000380244
ENST00000380244.7
EntrezGene:2521
EntrezGene:FUS
FUS
FUS-201
FUS-202
g4826733_3p_at
g4826733_3p_s_at
g4826733_3p_x_at
GE58786
GE646248
GE85981
GO:0000398
GO:0003674
GO:0003676
GO:0003677
GO:0003682
GO:0003713
GO:0003723
GO:0003729
GO:0003730
GO:0005515
GO:0005575
GO:0005622
GO:0005623
GO:0005634
GO:0005654
GO:0005737
GO:0005844
GO:0006259
GO:0006355
GO:0006357
GO:0006397
GO:0006950
GO:0008092
GO:0008134
GO:0008150
GO:0008380
GO:0009056
GO:0009058
GO:0010467
GO:0022607
GO:0030331
GO:0030425
GO:0031489
GO:0032991
GO:0034641
GO:0034655
GO:0035255
GO:0042802
GO:0043025
GO:0043167
GO:0043197
GO:0043204
GO:0043226
GO:0043484
GO:0044327
GO:0046872
GO:0046965
GO:0046966
GO:0048255
GO:0048471
GO:0051260
GO:0065003
GO:0071277
GO:1903508
GO:1905168
H3BNZ4
H3BPE7
HGNC:4010
HPA008784
Hs.99969.2.S1_3p_a_at
Hs.99969.2.S1_3p_s_at
Hs.99969.2.S1_3p_x_at
Hs.99969.3.S1_3p_at
Hs2.382749.1.S1_3p_x_at
Hs2.392171.1.S1_3p_s_at
ILMN_2306066
IPR000504
IPR001876
IPR012677
IPR034459
IPR034870
IPR035979
IPR036443
LRG_655
LRG_655t1
MIM:137070
MIM:608030
MIM:614782
NM_001170634
NM_001170937
NM_004960
NP_001164105
NP_001164408
NP_004951
NR_028388
PF00076
PF00641
PH_hs_0022279
PH_hs_0031515
Q6IBQ5
S62138
S62140
SM00360
SM00547
TC16000372.hg
TC16001494.hg
TC16001495.hg
UPI000002A9FB
UPI000012AD9A
X71427
X71428
X71428_at
XM_005255233
XM_011545781
XM_011545782
XM_024450221
XP_005255290
XP_011544083
XP_011544084
XP_024305989
Participant Of
input
hasComponent
Inferred To
Ghost homologue of FUS [nucleoplasm] (Dictyostelium discoideum)
Ghost homologue of FUS [nucleoplasm] (Plasmodium falciparum)
Ghost homologue of FUS [nucleoplasm] (Schizosaccharomyces pombe)
FUS [nucleoplasm] (Bos taurus)
FUS [nucleoplasm] (Caenorhabditis elegans)
FUS [nucleoplasm] (Canis familiaris)
FUS [nucleoplasm] (Danio rerio)
FUS [nucleoplasm] (Drosophila melanogaster)
FUS [nucleoplasm] (Gallus gallus)
FUS [nucleoplasm] (Mus musculus)
FUS [nucleoplasm] (Rattus norvegicus)
FUS [nucleoplasm] (Sus scrofa)
FUS [nucleoplasm] (Xenopus tropicalis)
Homologues of FUS [nucleoplasm] (Drosophila melanogaster)
Cross References
RefSeq
OpenTargets
GeneCards
PRO
Orphanet
PDB
Interactors (21)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:Q92804 TAF15  1 0.659 7
 UniProt:Q99873 PRMT1  2 0.657 5
 UniProt:P43243 MATR3      0.656 7
 UniProt:Q15424 SAFB  3 0.644 7
 UniProt:P35637 FUS  1 0.641 4
 UniProt:P45481 Crebbp  4 0.602 4
 UniProt:Q09472 EP300  5 0.591 4
 UniProt:Q99873-3 PRMT1      0.571 3
 UniProt:Q92973-2 TNPO1      0.558 2
 UniProt:Q15149 PLEC  3 0.556 4
 UniProt:Q01844 EWS      0.547 5
 UniProt:P38159 RBMX  1 0.547 5
 UniProt:Q92993 KAT5  1 0.524 2
 UniProt:Q9NRR4 DROSHA  1 0.524 2
 UniProt:Q08211 DHX9  2 0.512 8
 IntAct:EBI-6932561 FUS      0.512 4
 UniProt:Q6RFH8 DUX4C      0.463 2
 UniProt:Q9UBX2 DUX4      0.463 2
 UniProt:P09651 HNRNPA1  1 0.462 3
 UniProt:P03372 ESR1  8 0.462 2
 UniProt:Q12905 ILF2  4 0.462 7