Reactome | RBM5 [nucleoplasm]

RBM5 [nucleoplasm]

Stable Identifier

R-HSA-72049

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

RBM 5, RNA-binding protein 5, RNA binding motif protein 5, Putative tumor suppressor LUCA15, G15 protein

Locations in the PathwayBrowser for interactor UniProt:O43143 DHX15

Expand all

External Reference Information

External Reference

UniProt:P52756 RBM5

Gene Names

RBM5, H37, LUCA15

Chain

chain:1-815

Reference Genes

BioGPS Gene:10181 RBM5

COSMIC (genes):RBM5 RBM5

CTD Gene:10181 RBM5

dbSNP Gene:10181 RBM5

ENSEMBL:ENSG00000003756.17 RBM5

HGNC:9902 RBM5

KEGG Gene (Homo sapiens):10181 RBM5

Monarch:10181 RBM5

NCBI Gene:10181 RBM5

OMIM:606884 RBM5

UCSC:P52756 RBM5

Reference Transcript

Other Identifiers

0003140092

10181

11716007_a_at

11716008_x_at

11752280_a_at

11752281_x_at

11754588_a_at

11763377_a_at

1556_at

16940877

201394_PM_s_at

201394_s_at

201395_PM_at

201395_at

209936_PM_at

209936_at

2622470

2622471

2622473

2622475

2622486

2622487

2622488

2622489

2622490

2622491

2622492

2622493

2622494

2622495

2622496

2622497

2622498

2622500

2622502

2622503

2622504

2622505

2622506

2622507

2622509

2622510

2622516

2622517

2622519

2622522

2622524

2622529

2622531

2622533

2622534

32804_at

78085_at

8079869

89864_at

A_14_P103288

A_14_P115247

A_23_P18276

A_24_P328646

A_24_P919510

GE61282

GO:0000245

GO:0000381

GO:0000398

GO:0003676

GO:0003677

GO:0003723

GO:0003729

GO:0005515

GO:0005622

GO:0005634

GO:0005654

GO:0005681

GO:0006396

GO:0006397

GO:0006915

GO:0008285

GO:0008380

GO:0012501

GO:0016071

GO:0032991

GO:0042981

GO:0043065

GO:0043226

GO:0046872

GO:0065003

HMNXSV003038498

ILMN_1786893

PH_hs_0025747

TC03002333.hg

TC03003352.hg

U23946_at

g1244403_3p_a_at

g5032030_3p_at

g9801844_3p_at

Participates

as an output of

Formation of the Spliceosomal B complex (new) (Homo sapiens)

as an input of

Formation of the Spliceosomal A complex (update) (Homo sapiens)

as a component of

Inferred To

rbm5 [nucleoplasm] (Xenopus tropicalis)

RBM10 [nucleoplasm] (Gallus gallus)

RBM5 [nucleoplasm] (Bos taurus)

RBM5 [nucleoplasm] (Canis familiaris)

RBM5 [nucleoplasm] (Danio rerio)

RBM5 [nucleoplasm] (Dictyostelium discoideum)

RBM5 [nucleoplasm] (Schizosaccharomyces pombe)

RBM5 [nucleoplasm] (Sus scrofa)

Rbm5 [nucleoplasm] (Mus musculus)

Rbm5 [nucleoplasm] (Rattus norvegicus)

Ghost homologue of RBM5 [nucleoplasm] (Plasmodium falciparum)

rbm-5 [nucleoplasm] (Caenorhabditis elegans)

Dmel\CG4887 [nucleoplasm] (Drosophila melanogaster)

Cross References

RefSeq

NP_005769.1, XP_016860992.1

OpenTargets

ENSG00000003756

GeneCards

P52756

HPA

ENSG00000003756-RBM5

Ensembl

ENSP00000419534, ENST00000469838, ENSP00000343054, ENST00000347869, ENSG00000003756

PRO

P52756

Pharos - Targets

P52756

PDB

5MF9, 5MFY, 2LK1, 2LKZ, 2LK0

Interactors (14)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:O43143 DHX15	1	DHX15 [nucleoplasm] (R-HSA-5688097)	0.806	15
UniProt:Q9UMS4 PRPF19	1	PRPF19 [nucleoplasm] (R-HSA-5420907)	0.736	8
UniProt:P50221 MEOX1			0.601	4
UniProt:O95822-2 MLYCD	2	MLYCD(40-493) [cytosol] (R-HSA-9033089) MLYCD(40-493) [peroxisomal matrix] (R-HSA-2291936)	0.601	4
UniProt:P36957 DLST	2	DLST [mitochondrial matrix] (R-HSA-6792574) Lipo-K110-DLST [mitochondrial matrix] (R-HSA-69993)	0.556	3
UniProt:Q6FHY5 Q6FHY5			0.556	6
UniProt:Q8TDX7 NEK7	2	NEK7 [cytosol] (R-HSA-2530599) p-S195-NEK7 [cytosol] (R-HSA-2984246)	0.556	3
UniProt:P27797 CALR	6	CALR [integral component of lumenal side of endoplasmic reticulum membrane] (R-HSA-985502) CALR [endoplasmic reticulum lumen] (R-HSA-195905) CALR [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-HSA-8863866) CALR [phagocytic vesicle membrane] (R-HSA-1236879) CALR [extracellular region] (R-HSA-2197641) CALR [endocytic vesicle lumen] (R-HSA-2239448)	0.556	3
UniProt:Q92876 KLK6			0.556	3
UniProt:P42858 HTT	1	HTT [nucleoplasm] (R-HSA-9023590)	0.556	6
UniProt:P37173 TGFBR2	9	TGFBR2 Y470D [plasma membrane] (R-HSA-3640905) TGFBR2 E526Q [plasma membrane] (R-HSA-3645770) TGFBR2 D522N [plasma membrane] (R-HSA-3640907) TGFBR2 R528H [plasma membrane] (R-HSA-3640894) TGFBR2 R528C [plasma membrane] (R-HSA-3640899) TGFBR2 K128fs3 [cytosol] (R-HSA-3642173) TGFBR2 K128fs35 [cytosol] (R-HSA-3642166) NEDD8-K556,K567-TGFBR2 [plasma membrane] (R-HSA-4332222) TGFBR2 [plasma membrane] (R-HSA-170842)	0.556	3
UniProt:P02649 APOE	10	APOE-4 [extracellular region] (R-HSA-9711070) APOE [early endosome] (R-HSA-2429687) APOE [endosome lumen] (R-HSA-174804) APOE [endosome membrane] (R-HSA-174766) APOE [clathrin-coated endocytic vesicle membrane] (R-HSA-174651) APOE [plasma membrane] (R-HSA-174615) APOE [endocytic vesicle lumen] (R-HSA-3221641) p-APOE [endoplasmic reticulum lumen] (R-HSA-8956980) APOE [endoplasmic reticulum lumen] (R-HSA-6784908) APOE [extracellular region] (R-HSA-174646)	0.556	3
UniProt:P26368 U2AF2	1	U2AF2 [nucleoplasm] (R-HSA-71987)	0.525	2
UniProt:O15042 U2SURP	1	U2SURP [nucleoplasm] (R-HSA-8865950)	0.508	2

Cite Us!