The formation of the B complex is ATP-dependent, and both the 5' and 3' splice sites are essential for B complex assembly. The U4 and U6 snRNPS are extensively base-paired, and this U4:U6 complex associates with the U5 snRNP to form a tri-snRNP particle. This tri-snRNP particle then binds to the spliceosomal A complex, to form the spliceosomal B complex.
Rappsilber, J, Ryder, U, Lamond, AI, Mann, M
Hartmuth, K, Urlaub, H, Vornlocher, HP, Will, CL, Gentzel, M, Wilm, M, Lührmann, R
Deckert, J, Hartmuth, K, Boehringer, D, Behzadnia, N, Will, CL, Kastner, B, Stark, H, Urlaub, H, Lührmann, R
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