Formation of the Spliceosomal B Complex

Stable Identifier
R-HSA-72127
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

The formation of the B complex is ATP-dependent, and both the 5' and 3' splice sites are essential for B complex assembly. The U4 and U6 snRNPS are extensively base-paired, and this U4:U6 complex associates with the U5 snRNP to form a tri-snRNP particle. This tri-snRNP particle then binds to the spliceosomal A complex, to form the spliceosomal B complex.

Participants
Participant Of
Orthologous Events