The active C complex is formed due to a conformational change in the intermediate C complex. After formation of the active C complex, the splicing reactions occur very rapidly.

• Formation of the active Spliceosomal C (B*) complex (Arabidopsis thaliana)
• Formation of the active Spliceosomal C (B*) complex (Bos taurus)
• Formation of the active Spliceosomal C (B*) complex (Caenorhabditis elegans)
• Formation of the active Spliceosomal C (B*) complex (Canis familiaris)
• Formation of the active Spliceosomal C (B*) complex (Danio rerio)
• Formation of the active Spliceosomal C (B*) complex (Drosophila melanogaster)
• Formation of the active Spliceosomal C (B*) complex (Gallus gallus)
• Formation of the active Spliceosomal C (B*) complex (Mus musculus)
• Formation of the active Spliceosomal C (B*) complex (Oryza sativa)
• Formation of the active Spliceosomal C (B*) complex (Rattus norvegicus)
• Formation of the active Spliceosomal C (B*) complex (Sus scrofa)
• Formation of the active Spliceosomal C (B*) complex (Taeniopygia guttata)
• Formation of the active Spliceosomal C (B*) complex (Xenopus tropicalis)