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About
What is Reactome ?
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Release Calendar
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License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
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Table of Contents
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Docs
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Cytomics
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FAQ
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RPL10 [cytosol]
Stable Identifier
R-HSA-72402
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
60S ribosomal protein L10, QM protein, Tumor suppressor QM, Laminin receptor homolog
Locations in the PathwayBrowser
Expand all
Cellular responses to stimuli (Homo sapiens)
Cellular responses to stress (Homo sapiens)
Cellular response to starvation (Homo sapiens)
Response of EIF2AK4 (GCN2) to amino acid deficiency (Homo sapiens)
EIF2AK4 (GCN2) binds tRNA (Homo sapiens)
EIF2AK4:GCN1:80S ribosome:mRNA [cytosol] (Homo sapiens)
80S Ribosome:mRNA Complex [cytosol] (Homo sapiens)
80S ribosome [cytosol] (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL10,RPL10L [cytosol] (Homo sapiens)
RPL10 [cytosol] (Homo sapiens)
tRNA:EIF2AK4:GCN1:80S Ribosome:mRNA [cytosol] (Homo sapiens)
80S Ribosome:mRNA Complex [cytosol] (Homo sapiens)
80S ribosome [cytosol] (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL10,RPL10L [cytosol] (Homo sapiens)
RPL10 [cytosol] (Homo sapiens)
EIF2AK4 (GCN2) dimer autophosphorylates (Homo sapiens)
tRNA:EIF2AK4:GCN1:80S Ribosome:mRNA [cytosol] (Homo sapiens)
80S Ribosome:mRNA Complex [cytosol] (Homo sapiens)
80S ribosome [cytosol] (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL10,RPL10L [cytosol] (Homo sapiens)
RPL10 [cytosol] (Homo sapiens)
tRNA:p-T899-EIF2AK4:GCN1:80S Ribosome:mRNA [cytosol] (Homo sapiens)
80S Ribosome:mRNA Complex [cytosol] (Homo sapiens)
80S ribosome [cytosol] (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL10,RPL10L [cytosol] (Homo sapiens)
RPL10 [cytosol] (Homo sapiens)
IMPACT binds GCN1 (Homo sapiens)
GCN1:80S ribosome:mRNA [cytosol] (Homo sapiens)
80S Ribosome:mRNA Complex [cytosol] (Homo sapiens)
80S ribosome [cytosol] (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL10,RPL10L [cytosol] (Homo sapiens)
RPL10 [cytosol] (Homo sapiens)
IMPACT:GCN1:80S ribosome:mRNA [cytosol] (Homo sapiens)
80S Ribosome:mRNA Complex [cytosol] (Homo sapiens)
80S ribosome [cytosol] (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL10,RPL10L [cytosol] (Homo sapiens)
RPL10 [cytosol] (Homo sapiens)
p-T899-EIF2AK4 (GCN2) phosphorylates EIF2AS1 (Homo sapiens)
tRNA:p-T899-EIF2AK4:GCN1:80S Ribosome:mRNA [cytosol] (Homo sapiens)
80S Ribosome:mRNA Complex [cytosol] (Homo sapiens)
80S ribosome [cytosol] (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL10,RPL10L [cytosol] (Homo sapiens)
RPL10 [cytosol] (Homo sapiens)
Developmental Biology (Homo sapiens)
Nervous system development (Homo sapiens)
Axon guidance (Homo sapiens)
Signaling by ROBO receptors (Homo sapiens)
Regulation of expression of SLITs and ROBOs (Homo sapiens)
Translation of ROBO3.2 mRNA initiates NMD (Homo sapiens)
80S ribosome [cytosol] (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL10,RPL10L [cytosol] (Homo sapiens)
RPL10 [cytosol] (Homo sapiens)
Translated ROBO3.2 mRNA in complex with NMD-initiating UPF2 [cytosol] (Homo sapiens)
80S ribosome [cytosol] (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL10,RPL10L [cytosol] (Homo sapiens)
RPL10 [cytosol] (Homo sapiens)
Translation of ROBO3.2 mRNA is negatively regulated by NMD (Homo sapiens)
Translated ROBO3.2 mRNA in complex with NMD-initiating UPF2 [cytosol] (Homo sapiens)
80S ribosome [cytosol] (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL10,RPL10L [cytosol] (Homo sapiens)
RPL10 [cytosol] (Homo sapiens)
Disease (Homo sapiens)
Infectious disease (Homo sapiens)
Viral Infection Pathways (Homo sapiens)
Influenza Infection (Homo sapiens)
Influenza Viral RNA Transcription and Replication (Homo sapiens)
Viral mRNA Translation (Homo sapiens)
Synthesis of PB1-F2 (Homo sapiens)
80S ribosome [cytosol] (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL10,RPL10L [cytosol] (Homo sapiens)
RPL10 [cytosol] (Homo sapiens)
Viral Protein Synthesis (Homo sapiens)
80S ribosome [cytosol] (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL10,RPL10L [cytosol] (Homo sapiens)
RPL10 [cytosol] (Homo sapiens)
Metabolism (Homo sapiens)
Metabolism of amino acids and derivatives (Homo sapiens)
Selenoamino acid metabolism (Homo sapiens)
Selenocysteine synthesis (Homo sapiens)
80S:Met-tRNAi:mRNA:SECISBP2:Sec-tRNA(Sec):EEFSEC:GTP is hydrolysed to 80S:Met-tRNAi:mRNA:SECISBP2:Sec and EEFSEC:GDP by EEFSEC (Homo sapiens)
80S:Met-tRNAi:mRNA:SECISBP2:Sec [cytosol] (Homo sapiens)
80S:Met-tRNAi:mRNA [cytosol] (Homo sapiens)
80S ribosome [cytosol] (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL10,RPL10L [cytosol] (Homo sapiens)
RPL10 [cytosol] (Homo sapiens)
80S:Met-tRNAi:mRNA:SECISBP2:Sec-tRNA(Sec):EEFSEC:GTP [cytosol] (Homo sapiens)
80S:Met-tRNAi:mRNA [cytosol] (Homo sapiens)
80S ribosome [cytosol] (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL10,RPL10L [cytosol] (Homo sapiens)
RPL10 [cytosol] (Homo sapiens)
Sec-tRNA(Sec):EEFSEC:GTP binds to 80S Ribosome (Homo sapiens)
80S:Met-tRNAi:mRNA [cytosol] (Homo sapiens)
80S ribosome [cytosol] (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL10,RPL10L [cytosol] (Homo sapiens)
RPL10 [cytosol] (Homo sapiens)
80S:Met-tRNAi:mRNA:SECISBP2:Sec-tRNA(Sec):EEFSEC:GTP [cytosol] (Homo sapiens)
80S:Met-tRNAi:mRNA [cytosol] (Homo sapiens)
80S ribosome [cytosol] (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL10,RPL10L [cytosol] (Homo sapiens)
RPL10 [cytosol] (Homo sapiens)
Metabolism of RNA (Homo sapiens)
Nonsense-Mediated Decay (NMD) (Homo sapiens)
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) (Homo sapiens)
SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) (Homo sapiens)
SMG1:Phosphorylated UPF1:EJC:Translated mRNP [cytosol] (Homo sapiens)
Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Homo sapiens)
80S ribosome [cytosol] (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL10,RPL10L [cytosol] (Homo sapiens)
RPL10 [cytosol] (Homo sapiens)
SMG1:UPF1:EJC:Translated mRNP [cytosol] (Homo sapiens)
Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Homo sapiens)
80S ribosome [cytosol] (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL10,RPL10L [cytosol] (Homo sapiens)
RPL10 [cytosol] (Homo sapiens)
SMG6 hydrolyzes mRNA with premature termination codon (Homo sapiens)
Phosphorylated UPF1:SMG5:SMG7:SMG6:PP2A:Translated mRNP [cytosol] (Homo sapiens)
Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Homo sapiens)
80S ribosome [cytosol] (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL10,RPL10L [cytosol] (Homo sapiens)
RPL10 [cytosol] (Homo sapiens)
UPF1 binds an mRNP with a termination codon preceding an Exon Junction Complex (Homo sapiens)
SMG1:UPF1:EJC:Translated mRNP [cytosol] (Homo sapiens)
Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Homo sapiens)
80S ribosome [cytosol] (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL10,RPL10L [cytosol] (Homo sapiens)
RPL10 [cytosol] (Homo sapiens)
Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Homo sapiens)
80S ribosome [cytosol] (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL10,RPL10L [cytosol] (Homo sapiens)
RPL10 [cytosol] (Homo sapiens)
p-4S-UPF1 recruits SMG5, SMG7, SMG6, PNRC2, DCP1A, and PP2A (Homo sapiens)
Phosphorylated UPF1:SMG5:SMG7:SMG6:PP2A:Translated mRNP [cytosol] (Homo sapiens)
Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Homo sapiens)
80S ribosome [cytosol] (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL10,RPL10L [cytosol] (Homo sapiens)
RPL10 [cytosol] (Homo sapiens)
SMG1:Phosphorylated UPF1:EJC:Translated mRNP [cytosol] (Homo sapiens)
Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Homo sapiens)
80S ribosome [cytosol] (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL10,RPL10L [cytosol] (Homo sapiens)
RPL10 [cytosol] (Homo sapiens)
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) (Homo sapiens)
Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex (Homo sapiens)
Translated mRNA Complex with Premature Termination Codon Not Preceding Exon Junction [cytosol] (Homo sapiens)
80S ribosome [cytosol] (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL10,RPL10L [cytosol] (Homo sapiens)
RPL10 [cytosol] (Homo sapiens)
UPF1:eRF3 Complex on Translated mRNA [cytosol] (Homo sapiens)
Translated mRNA Complex with Premature Termination Codon Not Preceding Exon Junction [cytosol] (Homo sapiens)
80S ribosome [cytosol] (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL10,RPL10L [cytosol] (Homo sapiens)
RPL10 [cytosol] (Homo sapiens)
rRNA processing (Homo sapiens)
rRNA processing in the nucleus and cytosol (Homo sapiens)
Major pathway of rRNA processing in the nucleolus and cytosol (Homo sapiens)
12S pre-rRNA is nucleolytically processed to yield 5.8S rRNA (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL10,RPL10L [cytosol] (Homo sapiens)
RPL10 [cytosol] (Homo sapiens)
Metabolism of proteins (Homo sapiens)
Translation (Homo sapiens)
Eukaryotic Translation Elongation (Homo sapiens)
Peptide chain elongation (Homo sapiens)
Aminoacyl-tRNA binds to the ribosome at the A-site (Homo sapiens)
80S:Met-tRNAi:mRNA [cytosol] (Homo sapiens)
80S ribosome [cytosol] (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL10,RPL10L [cytosol] (Homo sapiens)
RPL10 [cytosol] (Homo sapiens)
80S:aminoacyl tRNA:mRNA:eEF1A:GTP [cytosol] (Homo sapiens)
80S:Met-tRNAi:mRNA [cytosol] (Homo sapiens)
80S ribosome [cytosol] (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL10,RPL10L [cytosol] (Homo sapiens)
RPL10 [cytosol] (Homo sapiens)
Hydrolysis of eEF1A:GTP (Homo sapiens)
80S ribosome [cytosol] (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL10,RPL10L [cytosol] (Homo sapiens)
RPL10 [cytosol] (Homo sapiens)
80S:Met-tRNAi:mRNA:aminoacyl-tRNA [cytosol] (Homo sapiens)
80S:Met-tRNAi:mRNA [cytosol] (Homo sapiens)
80S ribosome [cytosol] (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL10,RPL10L [cytosol] (Homo sapiens)
RPL10 [cytosol] (Homo sapiens)
80S:aminoacyl tRNA:mRNA:eEF1A:GTP [cytosol] (Homo sapiens)
80S:Met-tRNAi:mRNA [cytosol] (Homo sapiens)
80S ribosome [cytosol] (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL10,RPL10L [cytosol] (Homo sapiens)
RPL10 [cytosol] (Homo sapiens)
Peptide transfer from P-site tRNA to the A-site tRNA (Homo sapiens)
80S ribosome [cytosol] (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL10,RPL10L [cytosol] (Homo sapiens)
RPL10 [cytosol] (Homo sapiens)
80S:Met-tRNAi:mRNA:aminoacyl-tRNA [cytosol] (Homo sapiens)
80S:Met-tRNAi:mRNA [cytosol] (Homo sapiens)
80S ribosome [cytosol] (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL10,RPL10L [cytosol] (Homo sapiens)
RPL10 [cytosol] (Homo sapiens)
Elongation complex with growing peptide chain [cytosol] (Homo sapiens)
80S ribosome [cytosol] (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL10,RPL10L [cytosol] (Homo sapiens)
RPL10 [cytosol] (Homo sapiens)
Translocation of ribosome by 3 bases in the 3' direction (Homo sapiens)
80S Ribosome:mRNA:peptidyl-tRNA with elongating peptide [cytosol] (Homo sapiens)
80S ribosome [cytosol] (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL10,RPL10L [cytosol] (Homo sapiens)
RPL10 [cytosol] (Homo sapiens)
Elongation complex with growing peptide chain [cytosol] (Homo sapiens)
80S ribosome [cytosol] (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL10,RPL10L [cytosol] (Homo sapiens)
RPL10 [cytosol] (Homo sapiens)
Eukaryotic Translation Initiation (Homo sapiens)
Cap-dependent Translation Initiation (Homo sapiens)
Formation of a pool of free 40S subunits (Homo sapiens)
Release of 40S and 60S subunits from the 80S ribosome (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL10,RPL10L [cytosol] (Homo sapiens)
RPL10 [cytosol] (Homo sapiens)
80S ribosome [cytosol] (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL10,RPL10L [cytosol] (Homo sapiens)
RPL10 [cytosol] (Homo sapiens)
GTP hydrolysis and joining of the 60S ribosomal subunit (Homo sapiens)
The 60S subunit joins the translation initiation complex (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL10,RPL10L [cytosol] (Homo sapiens)
RPL10 [cytosol] (Homo sapiens)
80S:Met-tRNAi:mRNA:eIF5B:GTP [cytosol] (Homo sapiens)
80S ribosome [cytosol] (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL10,RPL10L [cytosol] (Homo sapiens)
RPL10 [cytosol] (Homo sapiens)
eIF5B:GTP is hydrolyzed and released (Homo sapiens)
80S:Met-tRNAi:mRNA [cytosol] (Homo sapiens)
80S ribosome [cytosol] (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL10,RPL10L [cytosol] (Homo sapiens)
RPL10 [cytosol] (Homo sapiens)
80S:Met-tRNAi:mRNA:eIF5B:GTP [cytosol] (Homo sapiens)
80S ribosome [cytosol] (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL10,RPL10L [cytosol] (Homo sapiens)
RPL10 [cytosol] (Homo sapiens)
L13a-mediated translational silencing of Ceruloplasmin expression (Homo sapiens)
Dissociation of L13a from the 60s ribosomal subunit (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL10,RPL10L [cytosol] (Homo sapiens)
RPL10 [cytosol] (Homo sapiens)
60s ribosomal complex lacking L13a subunit [cytosol] (Homo sapiens)
RPL10,RPL10L [cytosol] (Homo sapiens)
RPL10 [cytosol] (Homo sapiens)
Eukaryotic Translation Termination (Homo sapiens)
GTP Hydrolysis by eRF3 bound to the eRF1:mRNA:polypeptide:80S Ribosome complex (Homo sapiens)
Me-Q185-ETF1 dimer:eRF3:GDP:80S Ribosome:mRNA:peptidyl-tRNA Complex [cytosol] (Homo sapiens)
80S Ribosome:mRNA:peptidyl-tRNA with elongating peptide [cytosol] (Homo sapiens)
80S ribosome [cytosol] (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL10,RPL10L [cytosol] (Homo sapiens)
RPL10 [cytosol] (Homo sapiens)
Me-Q185-ETF1 dimer:eRF3:GTP:80S Ribosome:mRNA:peptidyl-tRNA [cytosol] (Homo sapiens)
80S Ribosome:mRNA:peptidyl-tRNA with elongating peptide [cytosol] (Homo sapiens)
80S ribosome [cytosol] (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL10,RPL10L [cytosol] (Homo sapiens)
RPL10 [cytosol] (Homo sapiens)
GTP bound eRF3:eRF1 complex binds the peptidyl tRNA:mRNA:80S Ribosome complex (Homo sapiens)
80S Ribosome:mRNA:peptidyl-tRNA with elongating peptide [cytosol] (Homo sapiens)
80S ribosome [cytosol] (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL10,RPL10L [cytosol] (Homo sapiens)
RPL10 [cytosol] (Homo sapiens)
Me-Q185-ETF1 dimer:eRF3:GTP:80S Ribosome:mRNA:peptidyl-tRNA [cytosol] (Homo sapiens)
80S Ribosome:mRNA:peptidyl-tRNA with elongating peptide [cytosol] (Homo sapiens)
80S ribosome [cytosol] (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL10,RPL10L [cytosol] (Homo sapiens)
RPL10 [cytosol] (Homo sapiens)
Polypeptide release from the eRF3-GDP:eRF1:mRNA:80S Ribosome complex (Homo sapiens)
Me-Q185-ETF1 dimer:eRF3:GDP:80S Ribosome:mRNA:peptidyl-tRNA Complex [cytosol] (Homo sapiens)
80S Ribosome:mRNA:peptidyl-tRNA with elongating peptide [cytosol] (Homo sapiens)
80S ribosome [cytosol] (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL10,RPL10L [cytosol] (Homo sapiens)
RPL10 [cytosol] (Homo sapiens)
Me-Q185-ETF1 dimer:eRF3:GDP:80S Ribosome:mRNA:tRNA Complex [cytosol] (Homo sapiens)
80S ribosome [cytosol] (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL10,RPL10L [cytosol] (Homo sapiens)
RPL10 [cytosol] (Homo sapiens)
SRP-dependent cotranslational protein targeting to membrane (Homo sapiens)
Nascent polypeptide:mRNA:ribosome complex binds signal recognition particle (SRP) (Homo sapiens)
SRP:polypeptide+signal:ribosome [cytosol] (Homo sapiens)
ribosome:mRNA:polypeptide+signal [cytosol] (Homo sapiens)
80S ribosome [cytosol] (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL10,RPL10L [cytosol] (Homo sapiens)
RPL10 [cytosol] (Homo sapiens)
ribosome:mRNA:polypeptide+signal [cytosol] (Homo sapiens)
80S ribosome [cytosol] (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL10,RPL10L [cytosol] (Homo sapiens)
RPL10 [cytosol] (Homo sapiens)
Signal peptidase hydrolyzes signal peptide from ribosome-associated nascent protein (Homo sapiens)
cleaved polypeptide:Translocon [endoplasmic reticulum membrane] (Homo sapiens)
membrane-bound ribosome:mRNA:cleaved polypeptide [endoplasmic reticulum membrane] (Homo sapiens)
80S ribosome [cytosol] (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL10,RPL10L [cytosol] (Homo sapiens)
RPL10 [cytosol] (Homo sapiens)
polypeptide+signal:Translocon [endoplasmic reticulum membrane] (Homo sapiens)
membrane-bound ribosome:mRNA:polypeptide+signal [endoplasmic reticulum membrane] (Homo sapiens)
80S ribosome [cytosol] (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL10,RPL10L [cytosol] (Homo sapiens)
RPL10 [cytosol] (Homo sapiens)
Signal-containing nascent peptide translocates to endoplasmic reticulum (Homo sapiens)
SRP receptor:SRP:ribosome:polypeptide+signal [endoplasmic reticulum membrane] (Homo sapiens)
SRP:polypeptide+signal:ribosome [cytosol] (Homo sapiens)
ribosome:mRNA:polypeptide+signal [cytosol] (Homo sapiens)
80S ribosome [cytosol] (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL10,RPL10L [cytosol] (Homo sapiens)
RPL10 [cytosol] (Homo sapiens)
polypeptide+signal:Translocon [endoplasmic reticulum membrane] (Homo sapiens)
membrane-bound ribosome:mRNA:polypeptide+signal [endoplasmic reticulum membrane] (Homo sapiens)
80S ribosome [cytosol] (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL10,RPL10L [cytosol] (Homo sapiens)
RPL10 [cytosol] (Homo sapiens)
Synthesis of nascent polypeptide containing signal sequence (Homo sapiens)
80S ribosome [cytosol] (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL10,RPL10L [cytosol] (Homo sapiens)
RPL10 [cytosol] (Homo sapiens)
ribosome:mRNA:polypeptide+signal [cytosol] (Homo sapiens)
80S ribosome [cytosol] (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL10,RPL10L [cytosol] (Homo sapiens)
RPL10 [cytosol] (Homo sapiens)
The SRP receptor binds the SRP:nascent peptide:ribosome complex (Homo sapiens)
SRP receptor:SRP:ribosome:polypeptide+signal [endoplasmic reticulum membrane] (Homo sapiens)
SRP:polypeptide+signal:ribosome [cytosol] (Homo sapiens)
ribosome:mRNA:polypeptide+signal [cytosol] (Homo sapiens)
80S ribosome [cytosol] (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL10,RPL10L [cytosol] (Homo sapiens)
RPL10 [cytosol] (Homo sapiens)
SRP:polypeptide+signal:ribosome [cytosol] (Homo sapiens)
ribosome:mRNA:polypeptide+signal [cytosol] (Homo sapiens)
80S ribosome [cytosol] (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL10,RPL10L [cytosol] (Homo sapiens)
RPL10 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:P27635 RPL10
Gene Names
RPL10, DXS648E, QM
Chain
initiator methionine:, chain:2-214
Reference Genes
BioGPS Gene:6134 RPL10
COSMIC (genes):RPL10 RPL10
CTD Gene:6134 RPL10
dbSNP Gene:6134 RPL10
ENSEMBL:ENSG00000147403 RPL10
HGNC:10298 RPL10
KEGG:hsa:6134 RPL10
Monarch:6134 RPL10
NCBI Gene:6134 RPL10
OMIM:312173 RPL10
UCSC:P27635 RPL10
Reference Transcript
RefSeq:NM_001303625.1 RPL10
RefSeq:NM_001303624.1 RPL10
RefSeq:NM_001256577.2 RPL10
RefSeq:NM_006013.4 RPL10
RefSeq:NM_001256580.2 RPL10
RefSeq:NM_001303626.1 RPL10
Other Identifiers
11715450_at
11757060_x_at
11757314_x_at
11757906_x_at
11763726_a_at
11763727_x_at
17119798
17122058
17123950
200724_PM_at
200724_at
200725_PM_x_at
200725_x_at
2016_s_at
221989_PM_at
221989_at
2374978
2526696
2526698
2839740
2839742
2839743
3222830
3222833
3461283
3796417
3820138
3820140
3820160
3851538
3851542
3851543
3851544
3927589
3929485
3996307
3996315
3996316
3996317
3996318
3996319
3996320
3996321
3996322
3996323
3996324
3996325
3996326
3996327
3996328
3996329
3996330
3996331
3996332
3996333
3996334
3996335
3996336
3996337
3996338
47953_at
6134
8025498
8109821
8170859
8170863
91064_s_at
A_14_P126601
A_14_P200625
A_21_P0000211
A_23_P217666
A_23_P324873
A_24_P6305
A_24_P754803
GE499149
GO:0000027
GO:0000122
GO:0002181
GO:0003723
GO:0003735
GO:0005198
GO:0005515
GO:0005634
GO:0005737
GO:0005783
GO:0005790
GO:0005829
GO:0005840
GO:0006355
GO:0006412
GO:0006417
GO:0016020
GO:0022625
GO:0022626
GO:0032991
GO:0043066
GO:0043226
GO:0045182
GO:0048856
GO:0065003
GO:1990403
GO:1990904
HMNXSV003000946
HMNXSV003003669
HMNXSV003018557
HMNXSV003022604
HMNXSV003034428
Hs.29797.4.A1_3p_at
ILMN_1695261
ILMN_1712250
ILMN_1730773
ILMN_2084182
PH_hs_0024608
PH_hs_0039956
RNA33473|snoRNA_scaRNA_69_135
RNA95169|RNS_251_186
RNA95471|RNS_553_154
TC0X000769.hg
TC0X001935.hg
TC19002342.hg
g13097176_3p_at
g5174430_3p_x_at
p26577
Participates
as a member of
RPL10,RPL10L [cytosol] (Homo sapiens)
Inferred To
rpl-10L [cytosol]
(Caenorhabditis elegans)
RpL10 [cytosol]
(Drosophila melanogaster)
Rpl10 [cytosol]
(Mus musculus)
Rpl10 [cytosol]
(Rattus norvegicus)
rpl10 [cytosol]
(Danio rerio)
rpl10 [cytosol]
(Dictyostelium discoideum)
rpl10 [cytosol]
(Xenopus tropicalis)
rpl1001 [cytosol]
(Schizosaccharomyces pombe)
Homologues of RPL10 [cytosol]
(Sus scrofa)
RPL10 [cytosol]
(Bos taurus)
RPL10 [cytosol]
(Canis familiaris)
RPL10 [cytosol]
(Plasmodium falciparum)
RPL10 [cytosol]
(Saccharomyces cerevisiae)
RPL10 [cytosol]
(Sus scrofa)
Cross References
OpenTargets
ENSG00000147403
ENSEMBL
ENSP00000358832
,
ENSP00000341730
,
ENST00000344746
,
ENST00000369817
,
ENSG00000147403
HPA
ENSG00000147403-RPL10
GeneCards
RPL10
PRO
P27635
Pharos - Targets
P27635
Orphanet
RPL10
GlyGen
P27635
PDB
8FLE
,
6OM7
,
8G6J
,
8FLD
,
8XSZ
,
8YOO
,
6OLZ
,
8YOP
,
8QFD
,
8A3D
,
8FLF
,
8G61
,
5AJ0
,
2PA2
,
8GLP
,
6OLG
,
6W6L
,
8K2C
,
8G5Z
,
8G60
,
8G5Y
,
6OLE
,
6OLF
,
6OLI
,
6OM0
,
8XSY
,
7F5S
,
9GMO
Interactors (8)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P03372 ESR1
10
ESR1 [cytosol]
(R-HSA-9020968)
ESR1 [nucleoplasm]
(R-HSA-446168)
Me260-PalmS-ESR1 [plasma membrane]
(R-HSA-9637788)
PalmS-ESR1 [plasma membrane]
(R-HSA-9021057)
PalmS-ESR1 [cytosol]
(R-HSA-9020974)
Me260-ESR1 [cytosol]
(R-HSA-9632177)
p-S167-ESR1 [cytosol]
(R-HSA-9841254)
p-S167-ESR1 [nucleoplasm]
(R-HSA-9841867)
monoSUMO1-5K-ESR1 [nucleoplasm]
(R-HSA-4090302)
p-S118-ESR1 [nucleoplasm]
(R-HSA-9024210)
0.597
4
UniProt:P12931 SRC
6
MyrG-p-Y419-SRC [plasma membrane]
(R-HSA-1810408)
MyrG,p-Y530-SRC [plasma membrane]
(R-HSA-377598)
MyrG-SRC [plasma membrane]
(R-HSA-8876922)
SRC [cytosol]
(R-HSA-9628701)
p-Y419-SRC [cytosol]
(R-HSA-8964276)
p-Y419-SRC [nucleoplasm]
(R-HSA-8937690)
0.591
6
UniProt:Q99558 MAP3K14
5
Active NIK [cytosol]
(R-HSA-5607646)
MAP3K14 [cytosol]
(R-HSA-168189)
p-MAP3K14 [cytosol]
(R-HSA-168187)
K48polyUb-NIK [cytosol]
(R-HSA-5668525)
p-T559-MAP3K14 [cytosol]
(R-HSA-5668531)
0.564
3
UniProt:P11388 TOP2A
3
TOP2A [nucleoplasm]
(R-HSA-1362276)
polySUMO2,3-TOP2A [nucleoplasm]
(R-HSA-4641298)
monoSUMO1-K-TOP2A [nucleoplasm]
(R-HSA-4641367)
0.527
2
UniProt:P63244 RACK1
1
RACK1 [cytosol]
(R-HSA-5626956)
0.527
2
UniProt:P62249 RPS16
2
RPS16 [cytosol]
(R-HSA-72337)
RPS16 [nucleoplasm]
(R-HSA-6791196)
0.527
2
UniProt:P13569 CFTR
17
misfolded CFTR [endoplasmic reticulum membrane]
(R-HSA-8868730)
CFTR [endoplasmic reticulum membrane]
(R-HSA-8866837)
CFTR [plasma membrane]
(R-HSA-383188)
CFTR N1303K [plasma membrane]
(R-HSA-5678983)
CFTR F508del [plasma membrane]
(R-HSA-5678978)
CFTR W1282* [plasma membrane]
(R-HSA-5678976)
CFTR G551D [plasma membrane]
(R-HSA-5678977)
CFTR G542* [plasma membrane]
(R-HSA-5678986)
ub-CFTR F508del [endoplasmic reticulum membrane]
(R-HSA-8866842)
ub-CFTR F508del [cytosol]
(R-HSA-8866838)
CFTR F508del [endoplasmic reticulum membrane]
(R-HSA-8866834)
PolyUb-CFTR [endosome membrane]
(R-HSA-6782976)
CFTR [endosome membrane]
(R-HSA-6782965)
CFTR [Golgi-associated vesicle membrane]
(R-HSA-5627079)
CFTR [lysosomal membrane]
(R-HSA-5627279)
PolyUb-CFTR [plasma membrane]
(R-HSA-8867595)
PolyUb-CFTR [clathrin-coated endocytic vesicle membrane]
(R-HSA-8869104)
0.527
12
UniProt:P0DTC9 N
13
SUMO1-K62-ADPr-p-11S,2T-metR95,177-N [cytosol]
(R-COV-9729340)
SUMO1-K62-ADPr-p-11S,2T-metR95,177-N [endoplasmic reticulum-Golgi intermediate compartment membrane]
(R-COV-9729341)
ADPr-p-11S,2T-metR95,177-N [cytosol]
(R-COV-9729275)
p-11S,2T-metR95,177-N [cytosol]
(R-COV-9729308)
p-11S,2T-N [cytosol]
(R-COV-9729264)
p-8S,2T-N [cytosol]
(R-COV-9729277)
p-8S-N [cytosol]
(R-COV-9729335)
p-S188,206-N [cytosol]
(R-COV-9729324)
N [cytosol]
(R-COV-9694300)
SUMO1-K62,ADPr-,p-11S,2T,met-R95,177,Ac-K375-N [cytosol]
(R-COV-9756489)
N [plasma membrane]
(R-COV-9694356)
SUMO1-K62-ADPr-p-11S,2T-metR95,177-N [nucleolus]
(R-COV-9729339)
SUMO1-K62-ADPr-p-11S,2T-metR95,177-N [plasma membrane]
(R-COV-9729325)
0.527
3
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