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What is Reactome ?
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RPL23 [cytosol]
Stable Identifier
R-HSA-72430
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
60S ribosomal protein L23, L17
Locations in the PathwayBrowser
Expand all
Cellular responses to stimuli (Homo sapiens)
Cellular responses to stress (Homo sapiens)
Cellular response to starvation (Homo sapiens)
Response of EIF2AK4 (GCN2) to amino acid deficiency (Homo sapiens)
EIF2AK4 (GCN2) binds tRNA (Homo sapiens)
EIF2AK4:GCN1:80S ribosome:mRNA [cytosol] (Homo sapiens)
80S Ribosome:mRNA Complex [cytosol] (Homo sapiens)
80S ribosome [cytosol] (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL23 [cytosol] (Homo sapiens)
tRNA:EIF2AK4:GCN1:80S Ribosome:mRNA [cytosol] (Homo sapiens)
80S Ribosome:mRNA Complex [cytosol] (Homo sapiens)
80S ribosome [cytosol] (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL23 [cytosol] (Homo sapiens)
EIF2AK4 (GCN2) dimer autophosphorylates (Homo sapiens)
tRNA:EIF2AK4:GCN1:80S Ribosome:mRNA [cytosol] (Homo sapiens)
80S Ribosome:mRNA Complex [cytosol] (Homo sapiens)
80S ribosome [cytosol] (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL23 [cytosol] (Homo sapiens)
tRNA:p-T899-EIF2AK4:GCN1:80S Ribosome:mRNA [cytosol] (Homo sapiens)
80S Ribosome:mRNA Complex [cytosol] (Homo sapiens)
80S ribosome [cytosol] (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL23 [cytosol] (Homo sapiens)
IMPACT binds GCN1 (Homo sapiens)
GCN1:80S ribosome:mRNA [cytosol] (Homo sapiens)
80S Ribosome:mRNA Complex [cytosol] (Homo sapiens)
80S ribosome [cytosol] (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL23 [cytosol] (Homo sapiens)
IMPACT:GCN1:80S ribosome:mRNA [cytosol] (Homo sapiens)
80S Ribosome:mRNA Complex [cytosol] (Homo sapiens)
80S ribosome [cytosol] (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL23 [cytosol] (Homo sapiens)
p-T899-EIF2AK4 (GCN2) phosphorylates EIF2AS1 (Homo sapiens)
tRNA:p-T899-EIF2AK4:GCN1:80S Ribosome:mRNA [cytosol] (Homo sapiens)
80S Ribosome:mRNA Complex [cytosol] (Homo sapiens)
80S ribosome [cytosol] (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL23 [cytosol] (Homo sapiens)
Developmental Biology (Homo sapiens)
Nervous system development (Homo sapiens)
Axon guidance (Homo sapiens)
Signaling by ROBO receptors (Homo sapiens)
Regulation of expression of SLITs and ROBOs (Homo sapiens)
Translation of ROBO3.2 mRNA initiates NMD (Homo sapiens)
80S ribosome [cytosol] (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL23 [cytosol] (Homo sapiens)
Translated ROBO3.2 mRNA in complex with NMD-initiating UPF2 [cytosol] (Homo sapiens)
80S ribosome [cytosol] (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL23 [cytosol] (Homo sapiens)
Translation of ROBO3.2 mRNA is negatively regulated by NMD (Homo sapiens)
Translated ROBO3.2 mRNA in complex with NMD-initiating UPF2 [cytosol] (Homo sapiens)
80S ribosome [cytosol] (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL23 [cytosol] (Homo sapiens)
Disease (Homo sapiens)
Infectious disease (Homo sapiens)
Viral Infection Pathways (Homo sapiens)
Influenza Infection (Homo sapiens)
Influenza Viral RNA Transcription and Replication (Homo sapiens)
Viral mRNA Translation (Homo sapiens)
Synthesis of PB1-F2 (Homo sapiens)
80S ribosome [cytosol] (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL23 [cytosol] (Homo sapiens)
Viral Protein Synthesis (Homo sapiens)
80S ribosome [cytosol] (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL23 [cytosol] (Homo sapiens)
Metabolism (Homo sapiens)
Metabolism of amino acids and derivatives (Homo sapiens)
Selenoamino acid metabolism (Homo sapiens)
Selenocysteine synthesis (Homo sapiens)
80S:Met-tRNAi:mRNA:SECISBP2:Sec-tRNA(Sec):EEFSEC:GTP is hydrolysed to 80S:Met-tRNAi:mRNA:SECISBP2:Sec and EEFSEC:GDP by EEFSEC (Homo sapiens)
80S:Met-tRNAi:mRNA:SECISBP2:Sec [cytosol] (Homo sapiens)
80S:Met-tRNAi:mRNA [cytosol] (Homo sapiens)
80S ribosome [cytosol] (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL23 [cytosol] (Homo sapiens)
80S:Met-tRNAi:mRNA:SECISBP2:Sec-tRNA(Sec):EEFSEC:GTP [cytosol] (Homo sapiens)
80S:Met-tRNAi:mRNA [cytosol] (Homo sapiens)
80S ribosome [cytosol] (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL23 [cytosol] (Homo sapiens)
Sec-tRNA(Sec):EEFSEC:GTP binds to 80S Ribosome (Homo sapiens)
80S:Met-tRNAi:mRNA [cytosol] (Homo sapiens)
80S ribosome [cytosol] (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL23 [cytosol] (Homo sapiens)
80S:Met-tRNAi:mRNA:SECISBP2:Sec-tRNA(Sec):EEFSEC:GTP [cytosol] (Homo sapiens)
80S:Met-tRNAi:mRNA [cytosol] (Homo sapiens)
80S ribosome [cytosol] (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL23 [cytosol] (Homo sapiens)
Metabolism of RNA (Homo sapiens)
Nonsense-Mediated Decay (NMD) (Homo sapiens)
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) (Homo sapiens)
SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) (Homo sapiens)
SMG1:Phosphorylated UPF1:EJC:Translated mRNP [cytosol] (Homo sapiens)
Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Homo sapiens)
80S ribosome [cytosol] (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL23 [cytosol] (Homo sapiens)
SMG1:UPF1:EJC:Translated mRNP [cytosol] (Homo sapiens)
Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Homo sapiens)
80S ribosome [cytosol] (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL23 [cytosol] (Homo sapiens)
SMG6 hydrolyzes mRNA with premature termination codon (Homo sapiens)
Phosphorylated UPF1:SMG5:SMG7:SMG6:PP2A:Translated mRNP [cytosol] (Homo sapiens)
Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Homo sapiens)
80S ribosome [cytosol] (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL23 [cytosol] (Homo sapiens)
UPF1 binds an mRNP with a termination codon preceding an Exon Junction Complex (Homo sapiens)
SMG1:UPF1:EJC:Translated mRNP [cytosol] (Homo sapiens)
Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Homo sapiens)
80S ribosome [cytosol] (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL23 [cytosol] (Homo sapiens)
Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Homo sapiens)
80S ribosome [cytosol] (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL23 [cytosol] (Homo sapiens)
p-4S-UPF1 recruits SMG5, SMG7, SMG6, PNRC2, DCP1A, and PP2A (Homo sapiens)
Phosphorylated UPF1:SMG5:SMG7:SMG6:PP2A:Translated mRNP [cytosol] (Homo sapiens)
Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Homo sapiens)
80S ribosome [cytosol] (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL23 [cytosol] (Homo sapiens)
SMG1:Phosphorylated UPF1:EJC:Translated mRNP [cytosol] (Homo sapiens)
Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Homo sapiens)
80S ribosome [cytosol] (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL23 [cytosol] (Homo sapiens)
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) (Homo sapiens)
Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex (Homo sapiens)
Translated mRNA Complex with Premature Termination Codon Not Preceding Exon Junction [cytosol] (Homo sapiens)
80S ribosome [cytosol] (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL23 [cytosol] (Homo sapiens)
UPF1:eRF3 Complex on Translated mRNA [cytosol] (Homo sapiens)
Translated mRNA Complex with Premature Termination Codon Not Preceding Exon Junction [cytosol] (Homo sapiens)
80S ribosome [cytosol] (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL23 [cytosol] (Homo sapiens)
rRNA processing (Homo sapiens)
rRNA processing in the nucleus and cytosol (Homo sapiens)
Major pathway of rRNA processing in the nucleolus and cytosol (Homo sapiens)
12S pre-rRNA is nucleolytically processed to yield 5.8S rRNA (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL23 [cytosol] (Homo sapiens)
Metabolism of proteins (Homo sapiens)
Translation (Homo sapiens)
Eukaryotic Translation Elongation (Homo sapiens)
Peptide chain elongation (Homo sapiens)
Aminoacyl-tRNA binds to the ribosome at the A-site (Homo sapiens)
80S:Met-tRNAi:mRNA [cytosol] (Homo sapiens)
80S ribosome [cytosol] (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL23 [cytosol] (Homo sapiens)
80S:aminoacyl tRNA:mRNA:eEF1A:GTP [cytosol] (Homo sapiens)
80S:Met-tRNAi:mRNA [cytosol] (Homo sapiens)
80S ribosome [cytosol] (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL23 [cytosol] (Homo sapiens)
Hydrolysis of eEF1A:GTP (Homo sapiens)
80S ribosome [cytosol] (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL23 [cytosol] (Homo sapiens)
80S:Met-tRNAi:mRNA:aminoacyl-tRNA [cytosol] (Homo sapiens)
80S:Met-tRNAi:mRNA [cytosol] (Homo sapiens)
80S ribosome [cytosol] (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL23 [cytosol] (Homo sapiens)
80S:aminoacyl tRNA:mRNA:eEF1A:GTP [cytosol] (Homo sapiens)
80S:Met-tRNAi:mRNA [cytosol] (Homo sapiens)
80S ribosome [cytosol] (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL23 [cytosol] (Homo sapiens)
Peptide transfer from P-site tRNA to the A-site tRNA (Homo sapiens)
80S ribosome [cytosol] (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL23 [cytosol] (Homo sapiens)
80S:Met-tRNAi:mRNA:aminoacyl-tRNA [cytosol] (Homo sapiens)
80S:Met-tRNAi:mRNA [cytosol] (Homo sapiens)
80S ribosome [cytosol] (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL23 [cytosol] (Homo sapiens)
Elongation complex with growing peptide chain [cytosol] (Homo sapiens)
80S ribosome [cytosol] (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL23 [cytosol] (Homo sapiens)
Translocation of ribosome by 3 bases in the 3' direction (Homo sapiens)
80S Ribosome:mRNA:peptidyl-tRNA with elongating peptide [cytosol] (Homo sapiens)
80S ribosome [cytosol] (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL23 [cytosol] (Homo sapiens)
Elongation complex with growing peptide chain [cytosol] (Homo sapiens)
80S ribosome [cytosol] (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL23 [cytosol] (Homo sapiens)
Eukaryotic Translation Initiation (Homo sapiens)
Cap-dependent Translation Initiation (Homo sapiens)
Formation of a pool of free 40S subunits (Homo sapiens)
Release of 40S and 60S subunits from the 80S ribosome (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL23 [cytosol] (Homo sapiens)
80S ribosome [cytosol] (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL23 [cytosol] (Homo sapiens)
GTP hydrolysis and joining of the 60S ribosomal subunit (Homo sapiens)
The 60S subunit joins the translation initiation complex (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL23 [cytosol] (Homo sapiens)
80S:Met-tRNAi:mRNA:eIF5B:GTP [cytosol] (Homo sapiens)
80S ribosome [cytosol] (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL23 [cytosol] (Homo sapiens)
eIF5B:GTP is hydrolyzed and released (Homo sapiens)
80S:Met-tRNAi:mRNA [cytosol] (Homo sapiens)
80S ribosome [cytosol] (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL23 [cytosol] (Homo sapiens)
80S:Met-tRNAi:mRNA:eIF5B:GTP [cytosol] (Homo sapiens)
80S ribosome [cytosol] (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL23 [cytosol] (Homo sapiens)
L13a-mediated translational silencing of Ceruloplasmin expression (Homo sapiens)
Dissociation of L13a from the 60s ribosomal subunit (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL23 [cytosol] (Homo sapiens)
60s ribosomal complex lacking L13a subunit [cytosol] (Homo sapiens)
RPL23 [cytosol] (Homo sapiens)
Eukaryotic Translation Termination (Homo sapiens)
GTP Hydrolysis by eRF3 bound to the eRF1:mRNA:polypeptide:80S Ribosome complex (Homo sapiens)
Me-Q185-ETF1 dimer:eRF3:GDP:80S Ribosome:mRNA:peptidyl-tRNA Complex [cytosol] (Homo sapiens)
80S Ribosome:mRNA:peptidyl-tRNA with elongating peptide [cytosol] (Homo sapiens)
80S ribosome [cytosol] (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL23 [cytosol] (Homo sapiens)
Me-Q185-ETF1 dimer:eRF3:GTP:80S Ribosome:mRNA:peptidyl-tRNA [cytosol] (Homo sapiens)
80S Ribosome:mRNA:peptidyl-tRNA with elongating peptide [cytosol] (Homo sapiens)
80S ribosome [cytosol] (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL23 [cytosol] (Homo sapiens)
GTP bound eRF3:eRF1 complex binds the peptidyl tRNA:mRNA:80S Ribosome complex (Homo sapiens)
80S Ribosome:mRNA:peptidyl-tRNA with elongating peptide [cytosol] (Homo sapiens)
80S ribosome [cytosol] (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL23 [cytosol] (Homo sapiens)
Me-Q185-ETF1 dimer:eRF3:GTP:80S Ribosome:mRNA:peptidyl-tRNA [cytosol] (Homo sapiens)
80S Ribosome:mRNA:peptidyl-tRNA with elongating peptide [cytosol] (Homo sapiens)
80S ribosome [cytosol] (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL23 [cytosol] (Homo sapiens)
Polypeptide release from the eRF3-GDP:eRF1:mRNA:80S Ribosome complex (Homo sapiens)
Me-Q185-ETF1 dimer:eRF3:GDP:80S Ribosome:mRNA:peptidyl-tRNA Complex [cytosol] (Homo sapiens)
80S Ribosome:mRNA:peptidyl-tRNA with elongating peptide [cytosol] (Homo sapiens)
80S ribosome [cytosol] (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL23 [cytosol] (Homo sapiens)
Me-Q185-ETF1 dimer:eRF3:GDP:80S Ribosome:mRNA:tRNA Complex [cytosol] (Homo sapiens)
80S ribosome [cytosol] (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL23 [cytosol] (Homo sapiens)
SRP-dependent cotranslational protein targeting to membrane (Homo sapiens)
Nascent polypeptide:mRNA:ribosome complex binds signal recognition particle (SRP) (Homo sapiens)
SRP:polypeptide+signal:ribosome [cytosol] (Homo sapiens)
ribosome:mRNA:polypeptide+signal [cytosol] (Homo sapiens)
80S ribosome [cytosol] (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL23 [cytosol] (Homo sapiens)
ribosome:mRNA:polypeptide+signal [cytosol] (Homo sapiens)
80S ribosome [cytosol] (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL23 [cytosol] (Homo sapiens)
Signal peptidase hydrolyzes signal peptide from ribosome-associated nascent protein (Homo sapiens)
cleaved polypeptide:Translocon [endoplasmic reticulum membrane] (Homo sapiens)
membrane-bound ribosome:mRNA:cleaved polypeptide [endoplasmic reticulum membrane] (Homo sapiens)
80S ribosome [cytosol] (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL23 [cytosol] (Homo sapiens)
polypeptide+signal:Translocon [endoplasmic reticulum membrane] (Homo sapiens)
membrane-bound ribosome:mRNA:polypeptide+signal [endoplasmic reticulum membrane] (Homo sapiens)
80S ribosome [cytosol] (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL23 [cytosol] (Homo sapiens)
Signal-containing nascent peptide translocates to endoplasmic reticulum (Homo sapiens)
SRP receptor:SRP:ribosome:polypeptide+signal [endoplasmic reticulum membrane] (Homo sapiens)
SRP:polypeptide+signal:ribosome [cytosol] (Homo sapiens)
ribosome:mRNA:polypeptide+signal [cytosol] (Homo sapiens)
80S ribosome [cytosol] (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL23 [cytosol] (Homo sapiens)
polypeptide+signal:Translocon [endoplasmic reticulum membrane] (Homo sapiens)
membrane-bound ribosome:mRNA:polypeptide+signal [endoplasmic reticulum membrane] (Homo sapiens)
80S ribosome [cytosol] (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL23 [cytosol] (Homo sapiens)
Synthesis of nascent polypeptide containing signal sequence (Homo sapiens)
80S ribosome [cytosol] (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL23 [cytosol] (Homo sapiens)
ribosome:mRNA:polypeptide+signal [cytosol] (Homo sapiens)
80S ribosome [cytosol] (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL23 [cytosol] (Homo sapiens)
The SRP receptor binds the SRP:nascent peptide:ribosome complex (Homo sapiens)
SRP receptor:SRP:ribosome:polypeptide+signal [endoplasmic reticulum membrane] (Homo sapiens)
SRP:polypeptide+signal:ribosome [cytosol] (Homo sapiens)
ribosome:mRNA:polypeptide+signal [cytosol] (Homo sapiens)
80S ribosome [cytosol] (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL23 [cytosol] (Homo sapiens)
SRP:polypeptide+signal:ribosome [cytosol] (Homo sapiens)
ribosome:mRNA:polypeptide+signal [cytosol] (Homo sapiens)
80S ribosome [cytosol] (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
RPL23 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:P62829 RPL23
Gene Names
RPL23
Chain
chain:1-140
Reference Genes
BioGPS Gene:9349 RPL23
COSMIC (genes):RPL23 RPL23
CTD Gene:9349 RPL23
dbSNP Gene:9349 RPL23
ENSEMBL:ENSG00000125691 RPL23
HGNC:10316 RPL23
KEGG:hsa:9349 RPL23
Monarch:9349 RPL23
NCBI Gene:9349 RPL23
OMIM:603662 RPL23
UCSC:P62829 RPL23
Reference Transcript
RefSeq:NM_000978.3 RPL23
Other Identifiers
11757148_at
11757422_x_at
16844031
16844044
16844046
200888_PM_s_at
200888_s_at
214744_PM_s_at
214744_s_at
215224_PM_at
215224_at
32394_s_at
32395_r_at
3755430
3755431
3755432
3755433
3755434
3755435
3755436
3755437
3755438
3755439
3755440
3755441
3755442
3755443
3755444
44288_at
58947_s_at
8014749
8014755
9349
A_21_P0000263
A_23_P26713
A_24_P205242
A_32_P30710
A_33_P3224265
GE88295
GO:0000122
GO:0001223
GO:0002181
GO:0003723
GO:0003735
GO:0005198
GO:0005515
GO:0005654
GO:0005730
GO:0005737
GO:0005829
GO:0005840
GO:0005925
GO:0006355
GO:0006396
GO:0006412
GO:0006610
GO:0006886
GO:0006913
GO:0008284
GO:0010628
GO:0016020
GO:0022625
GO:0022626
GO:0031625
GO:0032986
GO:0032991
GO:0043226
GO:0045202
GO:0050821
GO:0070062
GO:0070180
GO:0070314
GO:0072717
GO:0098772
GO:1901798
GO:1903450
GO:1904667
GO:1990904
GO:1990948
GO:2000059
HMNXSV003000268
HMNXSV003012118
HMNXSV003019460
Hs.313509.0.S1_3p_s_at
Hs.322680.0.S1_3p_at
ILMN_1755115
PH_hs_0039543
RNA33494|snoRNA_scaRNA_90_133
TC17001437.hg
TC17001438.hg
X55954_at
g4506604_3p_s_at
Participates
as a component of
60s ribosomal complex lacking L13a subunit [cytosol] (Homo sapiens)
60S ribosomal complex [cytosol] (Homo sapiens)
Inferred To
RPL23A [cytosol]
(Saccharomyces cerevisiae)
rpl2302 [cytosol]
(Schizosaccharomyces pombe)
RPL23 [cytosol]
(Bos taurus)
RPL23 [cytosol]
(Canis familiaris)
RPL23 [cytosol]
(Gallus gallus)
RPL23 [cytosol]
(Plasmodium falciparum)
RPL23 [cytosol]
(Sus scrofa)
RPL23B [cytosol]
(Saccharomyces cerevisiae)
rpl-23 [cytosol]
(Caenorhabditis elegans)
rpl23 [cytosol]
(Danio rerio)
rpl23 [cytosol]
(Dictyostelium discoideum)
rpl23 [cytosol]
(Xenopus tropicalis)
rpl2301 [cytosol]
(Schizosaccharomyces pombe)
RpL23 [cytosol]
(Drosophila melanogaster)
Rpl23 [cytosol]
(Mus musculus)
Rpl23 [cytosol]
(Rattus norvegicus)
Homologues of RPL23 [cytosol]
(Saccharomyces cerevisiae)
Homologues of RPL23 [cytosol]
(Schizosaccharomyces pombe)
Cross References
RefSeq
NP_000969.1
OpenTargets
ENSG00000125691
ENSEMBL
ENST00000394332
,
ENSP00000377865
,
ENST00000479035
,
ENSP00000420311
HPA
ENSG00000125691-RPL23
PRO
P62829
Pharos - Targets
P62829
GlyGen
P62829
PDB
8FL2
,
6LU8
,
8IPX
,
8OHD
,
8FKT
,
5T2C
,
8FKS
,
7F5S
,
8FKZ
,
8G6J
,
5LKS
,
8FL3
,
8FLF
,
8IFE
,
8G61
,
8G5Y
,
6ZMI
,
8Y0W
,
6OLZ
,
8G5Z
,
6Z6M
,
6LSS
,
6Y0G
,
8JDM
,
8INF
,
8JDK
,
6OLG
,
4V6X
,
7XNY
,
6Z6N
,
8FLB
,
8INK
,
8FLD
,
8FLC
,
8IDT
,
8FL9
,
8FKU
,
6IP6
,
6IP5
,
8IPD
,
6Y2L
,
6XA1
,
8FKV
,
8IR3
,
8IR1
,
8FKQ
,
8FL4
,
8FKR
,
8IPY
,
5AJ0
,
8GLP
,
8FKY
,
8OJ0
,
6QZP
,
6ZM7
,
6OM7
,
8IE3
,
4UG0
,
8INE
,
7XNX
,
8OJ5
,
6OLE
,
8JDJ
,
8JDL
,
6OLF
,
8QFD
,
6Z6L
,
6Y6X
,
6OLI
,
8G60
,
7OW7
,
6OM0
,
6LSR
,
8A3D
,
8Y0X
,
8FLA
,
8OJ8
,
6ZMO
,
8IFD
,
8FLE
,
8FL6
,
8FKX
,
8FKW
,
8FKP
,
6LQM
,
6ZME
,
8IDY
,
8FL0
,
6IP8
,
6Y57
,
8FL7
Interactors (9)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q00987 MDM2
11
p-S166,S188-MDM2 [nucleoplasm]
(R-HSA-6793669)
p-S166,S188-MDM2 [cytosol]
(R-HSA-198638)
MDM2 [cytosol]
(R-HSA-198644)
MDM2 [nucleoplasm]
(R-HSA-69486)
MDM2 [endocytic vesicle membrane]
(R-HSA-416849)
MDM2 [plasma membrane]
(R-HSA-416843)
PolyUb,p-S166,S188-MDM2 [nucleoplasm]
(R-HSA-6795669)
p-5S,T-MDM2 [nucleoplasm]
(R-HSA-6804954)
p-S166,S188,T218-MDM2 [nucleoplasm]
(R-HSA-6792862)
monoSUMO1-K182-MDM2 [nucleoplasm]
(R-HSA-3000408)
PolyUb-MDM2 [nucleoplasm]
(R-HSA-6782472)
0.573
3
UniProt:Q99558 MAP3K14
5
Active NIK [cytosol]
(R-HSA-5607646)
MAP3K14 [cytosol]
(R-HSA-168189)
p-MAP3K14 [cytosol]
(R-HSA-168187)
K48polyUb-NIK [cytosol]
(R-HSA-5668525)
p-T559-MAP3K14 [cytosol]
(R-HSA-5668531)
0.564
3
UniProt:P10636-8 MAPT
3
MAPT-8 [cytosol]
(R-HSA-9619519)
p-S262,S356,S396-MAPT-8 [cytosol]
(R-HSA-9619521)
p-S199,S202,S262,S396,S404,S409,T181,T231-MAPT-8 [cytosol]
(R-HSA-9836400)
0.527
5
UniProt:Q5S007 LRRK2
1
LRRK2 [cytosol]
(R-HSA-5661173)
0.527
3
UniProt:P07437 TUBB
3
TUBB [extracellular region]
(R-HSA-380317)
TUBB [azurophil granule lumen]
(R-HSA-6799370)
TUBB [cytosol]
(R-HSA-9020816)
0.527
3
UniProt:Q07954 LRP1
2
LRP1 [endocytic vesicle membrane]
(R-HSA-2230981)
LRP1 [plasma membrane]
(R-HSA-1454844)
0.527
2
UniProt:P17980 PSMC3
5
PSMC3 [cytosol]
(R-HSA-68774)
PSMC3 [nucleoplasm]
(R-HSA-174313)
PSMC3 [secretory granule lumen]
(R-HSA-6800917)
PSMC3 [extracellular region]
(R-HSA-6806496)
PSMC3 [ficolin-1-rich granule lumen]
(R-HSA-6800429)
0.527
3
UniProt:P63244 RACK1
1
GNB2L1 [cytosol]
(R-HSA-5626956)
0.495
2
UniProt:P13569 CFTR
17
misfolded CFTR [endoplasmic reticulum membrane]
(R-HSA-8868730)
CFTR [endoplasmic reticulum membrane]
(R-HSA-8866837)
CFTR [plasma membrane]
(R-HSA-383188)
CFTR N1303K [plasma membrane]
(R-HSA-5678983)
CFTR F508del [plasma membrane]
(R-HSA-5678978)
CFTR W1282* [plasma membrane]
(R-HSA-5678976)
CFTR G551D [plasma membrane]
(R-HSA-5678977)
CFTR G542* [plasma membrane]
(R-HSA-5678986)
ub-CFTR F508del [endoplasmic reticulum membrane]
(R-HSA-8866842)
ub-CFTR F508del [cytosol]
(R-HSA-8866838)
CFTR F508del [endoplasmic reticulum membrane]
(R-HSA-8866834)
PolyUb-CFTR [endosome membrane]
(R-HSA-6782976)
CFTR [endosome membrane]
(R-HSA-6782965)
CFTR [Golgi-associated vesicle membrane]
(R-HSA-5627079)
CFTR [lysosomal membrane]
(R-HSA-5627279)
PolyUb-CFTR [plasma membrane]
(R-HSA-8867595)
PolyUb-CFTR [clathrin-coated endocytic vesicle membrane]
(R-HSA-8869104)
0.483
12
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