The 60S subunit joins the translation initiation complex

Stable Identifier
Reaction [binding]
Homo sapiens
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Joining of the 60S subunit to form the 80S ribosome is catalyzed by the presence of GTP-bound eIF5B.

Literature References
PubMed ID Title Journal Year
10659855 The joining of ribosomal subunits in eukaryotes requires eIF5B.

Pestova, TV, Lomakin, IB, Lee, JH, Choi, SK, Dever, TE, Hellen, CU

Nature 2000
1095581 Purification and characterization of homogeneous initiation factor M2A from rabbit reticulocytes.

Merrick, WC, Kemper, WM, Anderson, WF

J Biol Chem 1975
592398 Initiation of mammalian protein synthesis. I. Purification and characterization of seven initiation factors.

Schreier, MH, Erni, B, Staehelin, T

J Mol Biol 1978
Participant Of
Orthologous Events
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