beta-ureidopropionate + H2O => beta-alanine + NH4+ + CO2

Stable Identifier
R-HSA-73591
Type
Reaction [transition]
Species
Homo sapiens
Compartment
Synonyms
conversion of 3-ureidopropionate to beta-alanine
Locations in the PathwayBrowser
General
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Cytosolic 3-ureidopropionase catalyzes the reaction of 3-ureidopropionate and water to form beta-alanine, CO2, and NH3 (van Kuilenberg et al. 2004).

Literature References
PubMed ID Title Journal Year
15385443 beta-Ureidopropionase deficiency: an inborn error of pyrimidine degradation associated with neurological abnormalities

van Kuilenberg, AB, Meinsma, R, Beke, E, Assmann, B, Ribes, A, Lorente, I, Busch, R, Mayatepek, E, Abeling, NG, van Cruchten, A, Stroomer, AE, van Lenthe, H, Zoetekouw, L, Kulik, W, Hoffmann, GF, Voit, T, Wevers, RA, Rutsch, F, van Gennip, AH

Hum Mol Genet 2004
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
beta-ureidopropionase activity of UPB1:Zn2+ [cytosol]
Physical Entity
Activity
Orthologous Events
Cross References
Rhea
Authored
Created