Reactome: A Curated Pathway Database

cytidine or uridine + ATP => CMP or UMP + ADP [UCK1]

Stable Identifier
R-HSA-73599
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

Cytosolic uridine-cytidine kinase 1 (UCK1) catalyzes the reactions of cytidine or uridine with ATP to form CMP or UMP and ADP (Greenberg et al. 1977; Van Rompay et al. 2001). Unpublished crystallographic data show the enzyme to be a tetramer (PDB - 2JEO).

Literature References
Participants
Participant Of
This entity is regulated by:
Title Physical Entity Activity
nucleoside kinase activity of UCK1 tetramer [cytosol] UCK1 tetramer [cytosol] nucleoside kinase activity (0019206)
Orthologous Events