(deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA)

Stable Identifier
R-HSA-73608
Type
Reaction
Species
Homo sapiens
Compartment
cytosol
Synonyms
deamination of 2'-Deoxycytidine to 2'-Deoxyuridine
Locations in the PathwayBrowser
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Summation

Cytosolic cytidine deaminase catalyzes the hydrolysis of cytidine or dexoycytidine to form uridine or deoxyuridine and ammonia (Laliberte and Momparler 1994). The active form of the enzyme is a tetramer (Chung et al. 2005).

Literature References
Participants
Input
Output
Participant Of
hasEvent
Catalyst Activity
Catalyst Activity
Title
cytidine deaminase activity of CDA tetramer [cytosol]
Physical Entity
CDA tetramer [cytosol]
Activity
cytidine deaminase activity (0004126)
Orthologous Events
(deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) (Bos taurus)
(deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) (Caenorhabditis elegans)
(deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) (Canis familiaris)
(deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) (Danio rerio)
(deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) (Dictyostelium discoideum)
(deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) (Drosophila melanogaster)
(deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) (Gallus gallus)
(deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) (Mus musculus)
(deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) (Rattus norvegicus)
(deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) (Saccharomyces cerevisiae)
(deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) (Schizosaccharomyces pombe)
(deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) (Sus scrofa)
(deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) (Taeniopygia guttata)