Reactome: A Curated Pathway Database

(deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA)

Stable Identifier
R-HSA-73608
Type
Reaction
Species
Homo sapiens
Compartment
Synonyms
deamination of 2'-Deoxycytidine to 2'-Deoxyuridine
Locations in the PathwayBrowser
Summation

Cytosolic cytidine deaminase catalyzes the hydrolysis of cytidine or dexoycytidine to form uridine or deoxyuridine and ammonia (Laliberte and Momparler 1994). The active form of the enzyme is a tetramer (Chung et al. 2005).

Literature References
Participants
Participant Of
This entity is regulated by:
Title Physical Entity Activity
cytidine deaminase activity of CDA tetramer [cytosol] CDA tetramer [cytosol] cytidine deaminase activity (0004126)
Orthologous Events