5,6-dihydrothymine + H2O => beta-ureidoisobutyrate

Stable Identifier
R-HSA-73618
Type
Reaction [transition]
Species
Homo sapiens
Compartment
Synonyms
conversion of 5,6-Dihydrothymine to 3-Ureidoisobutyrate
Locations in the PathwayBrowser
General
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Cytosolic dihydropyrimidinase tetramer catalyzes the reaction of 5,6-dihydrothymine and water to yield 3-ureidoisobutyrate (Hamajima et al. 1998).

Literature References
PubMed ID Title Journal Year
9718352 Dihydropyrimidinase deficiency: structural organization, chromosomal localization, and mutation analysis of the human dihydropyrimidinase gene

Hamajima, N, Kouwaki, M, Vreken, P, Matsuda, K, Sumi, S, Imaeda, M, Ohba, S, Kidouchi, K, Nonaka, M, Sasaki, M, Tamaki, N, Endo, Y, De Abreu, R, Rotteveel, J, van Kuilenburg, A, van Gennip, A, Togari, H, Wada, Y

Am J Hum Genet 1998
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
dihydropyrimidinase activity of DPYS tetramer [cytosol]
Physical Entity
Activity
Orthologous Events
Cross References
Rhea
Created