thioredoxin, oxidized + NADPH + H+ => thioredoxin, reduced + NADP+

Stable Identifier
R-HSA-73646
Type
Reaction
Species
Homo sapiens
Compartment
Synonyms
regeneration of active (reduced) Thioredoxin
Locations in the PathwayBrowser
Summation

Cytosolic thioredoxin reductase catalyzes the reaction of thioredoxin, oxidized and NADPH + H+ to form thioredoxin, reduced and NADP+ (Urig et al. 2006).

Literature References
PubMed ID Title Journal Year
16750198 Truncated mutants of human thioredoxin reductase 1 do not exhibit glutathione reductase activity

Urig, S, Lieske, J, Fritz-Wolf, K, Irmler, A, Becker, K

FEBS Lett 2006
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
thioredoxin-disulfide reductase activity of TNXRD1:FAD dimer [cytosol]
Physical Entity
Activity
Orthologous Events
Authored
Reviewed