RNA Polymerase I Promoter Opening

Stable Identifier
R-HSA-73728
Type
Pathway
Species
Homo sapiens
Compartment
nucleolus
ReviewStatus
5/5
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RNA Polymerase I Promoter Opening
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The activity of the upstream binding factor (UBF-1) plays an important role in the regulation of rRNA synthesis. Studies reveal that phosphorylation of UBF-1 is required for its interaction with the RNA polymerase I complex, suggesting that phosphorylation of UBF-1 bound to the rDNA promoter during promoter opening modulates the assembly of the transcription initiation complex.
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Event Information
Go Biological Process
transcription initiation from RNA polymerase I promoter (0006361)
Orthologous Events
RNA Polymerase I Promoter Opening (Bos taurus)
RNA Polymerase I Promoter Opening (Canis familiaris)
RNA Polymerase I Promoter Opening (Danio rerio)
RNA Polymerase I Promoter Opening (Gallus gallus)
RNA Polymerase I Promoter Opening (Mus musculus)
RNA Polymerase I Promoter Opening (Rattus norvegicus)
RNA Polymerase I Promoter Opening (Sus scrofa)
RNA Polymerase I Promoter Opening (Xenopus tropicalis)
Authored
Comai, L  (2003-07-03)
Created
Comai, L  (2003-07-03)
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