Loss of Rrn3 from RNA Polymerase I promoter escape complex

Stable Identifier
R-HSA-73769
Type
Reaction [dissociation]
Species
Homo sapiens
Compartment
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Upon transcription initiation it is thought that RRN3 is inactivated and dissociates from the Loss of Rrn3 from the RNA Polymerase I promoter escape complex. SL1 and UBF are thought to remain bound to the promoter for multiple rounds of transcription initiation

Literature References
PubMed ID Title Journal Year
12646563 Rrn3 becomes inactivated in the process of ribosomal DNA transcription.

Hirschler-Laszkiewicz, I, Cavanaugh, AH, Mirza, A, Lun, M, Hu, Q, Smink, T, Rothblum, LI

J Biol Chem 2003
Participants
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