acetoacetic acid + NADH + H+ <=> beta-hydroxybutyrate + NAD+

Stable Identifier
R-HSA-73912
Type
Reaction [transition]
Species
Homo sapiens
Compartment
Synonyms
Reduction of Acetoacetate to beta-Hydroxybutyrate
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D-beta-hydroxybutyrate dehydrogenase tetramer (BDH1) in the mitochondrial matris catalyzes the reversible reaction of acetoacetate with NADH + H+ to form D-beta hydroxybutyrate and NAD+ (Marks et al. 1992).

Literature References
PubMed ID Title Journal Year
1639787 Molecular cloning and characterization of (R)-3-hydroxybutyrate dehydrogenase from human heart

Marks, AR, McIntyre, JO, Duncan, TM, Erdjument-Bromage, H, Tempst, P, Fleischer, S

J Biol Chem 1992
Participants
Participant Of
Event Information
Catalyst Activity
Catalyst Activity
Title
3-hydroxybutyrate dehydrogenase activity of BDH1 tetramer [mitochondrial matrix]
Physical Entity
Activity
Orthologous Events
Cross References
Rhea
Created