Base-Excision Repair, AP Site Formation

Stable Identifier
R-HSA-73929
Type
Pathway
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
General
SVG |   | PPTX  | SBGN
Click the image above or here to open this pathway in the Pathway Browser

Base excision repair is initiated by DNA glycosylases that hydrolytically cleave the base-deoxyribose glycosyl bond of a damaged nucleotide residue, releasing the damaged base (Lindahl and Wood 1999, Sokhansanj et al. 2002).

Literature References
PubMed ID Title Journal Year
10583946 Quality control by DNA repair

Lindahl, T, Wood, RD

Science 1999
11937636 A quantitative model of human DNA base excision repair. I. Mechanistic insights

Sokhansanj, BA, Rodrigue, GR, Fitch, JP, Wilson DM, 3rd

Nucleic Acids Res 2002
Participants
Participant Of
Event Information
Orthologous Events
Authored
Reviewed
Created