SLC35A3 exchanges UDP-GlcNAc for UMP

Stable Identifier
R-HSA-741450
Type
Reaction [transition]
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
General
SVG |   | PPTX  | SBGN
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

The human gene SLC35A3 encodes a UDP-GlcNAc transporter (Ishida et al. 1999). It is ubiquitously expressed and resides on the Golgi membrane where it transports UDP- N-acetylglucosamine (GlcNAc) into the Golgi lumen in exchange for UMP.

Literature References
PubMed ID Title Journal Year
10393322 Molecular cloning and functional expression of the human Golgi UDP-N-acetylglucosamine transporter

Ishida, N, Yoshioka, S, Chiba, Y, Takeuchi, M, Kawakita, M

J Biochem 1999
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
UDP-N-acetylglucosamine transmembrane transporter activity of SLC35A3 [Golgi membrane]
Physical Entity
Activity
Orthologous Events
Authored
Reviewed
Created