SLC35D2 exchanges UDP-sugars for UMP

Stable Identifier
R-HSA-744231
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

The human gene SLC35D2 encodes the UDP-N-acetylglucosamine/UDP-glucose/GDP-mannose transporter (UGTREL8; homolog of Fringe connection protein 1, HFRC1). It resides on the Golgi membrane where it mediates the transport of nucleotide sugars such as UDP-GlcNAc and UDP-glucose into the Golgi lumen in exchange for UMP (Suda et al. 2004, Ishida et al. 2005).

Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
nucleotide-sugar transmembrane transporter activity of SLC35D2 [Golgi membrane]
Physical Entity
Activity
Orthologous Events