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GUCY2F [photoreceptor disc membrane]
Stable Identifier
R-HSA-74919
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
photoreceptor disc membrane
Synonyms
Retinal guanylyl cyclase 2 precursor , Guanylate cyclase 2F, retinal, RETGC-2, Rod outer segment membrane guanylate cyclase 2, ROS-GC2, Guanylate cyclase F, GC-F
Icon
Locations in the PathwayBrowser
Expand all
Sensory Perception (Homo sapiens)
Visual phototransduction (Homo sapiens)
The phototransduction cascade (Homo sapiens)
Inactivation, recovery and regulation of the phototransduction cascade (Homo sapiens)
GUCYs converts GTP to cGMP (Homo sapiens)
GUCYs [photoreceptor disc membrane] (Homo sapiens)
GUCY2F [photoreceptor disc membrane] (Homo sapiens)
Literature References
PubMed ID
Title
Journal
Year
7777544
Cloning and expression of a second photoreceptor-specific membrane retina guanylyl cyclase (RetGC), RetGC-2.
Lowe, DG
,
Lu, L
,
Spencer, M
,
Laura, R
,
Liu, K
,
Gu, Q
,
Dizhoor, AM
,
Hurley, JB
Proc Natl Acad Sci U S A
1995
External Reference Information
External Reference
UniProt:P51841 GUCY2F
Gene Names
GUCY2F, GUC2F, RETGC2
Chain
signal peptide:1-50, chain:51-1108
Reference Genes
BioGPS Gene:2986 GUCY2F
COSMIC (genes):GUCY2F GUCY2F
CTD Gene:2986 GUCY2F
dbSNP Gene:2986 GUCY2F
ENSEMBL:ENSG00000101890 GUCY2F
ENSEMBL_homo_sapiens_GENE:ENSG00000101890.5 GUCY2F
HGNC:4691 GUCY2F
KEGG Gene (Homo sapiens):2986 GUCY2F
Monarch:2986 GUCY2F
NCBI Gene:2986 GUCY2F
OMIM:300041 GUCY2F
UCSC:P51841 GUCY2F
Reference Transcript
RefSeq:NM_001522.2 GUCY2F
Other Identifiers
11756102_a_at
17113264
208053_PM_at
208053_at
2986
39874_at
4017748
4017749
4017750
4017751
4017752
4017754
4017755
4017756
4017757
4017758
4017761
4017762
4017763
4017764
4017766
4017767
4017768
4017769
4017770
4017771
4017772
4017774
4017775
4017776
4017777
4017779
4017781
4017782
8174448
A_23_P360302
GE509190
GO:0000166
GO:0001653
GO:0003824
GO:0004016
GO:0004383
GO:0004672
GO:0005524
GO:0005525
GO:0005634
GO:0005635
GO:0005640
GO:0005886
GO:0005929
GO:0006182
GO:0006468
GO:0007168
GO:0007601
GO:0009190
GO:0009975
GO:0016020
GO:0016740
GO:0016829
GO:0016849
GO:0019934
GO:0022400
GO:0023052
GO:0035556
GO:0036211
GO:0038023
GO:0042802
GO:0042995
GO:0043226
GO:0044877
GO:0050877
GO:0050896
GO:0050908
GO:0055086
GO:0060089
GO:0097381
GO:0120200
GO:0140096
GO:1901135
HMNXSV003020698
ILMN_1723686
L37378_at
PH_hs_0027800
TC0X001270.hg
g4504218_3p_at
Participates
as a member of
GUCYs [photoreceptor disc membrane] (Homo sapiens)
Inferred To
gcy-1 [photoreceptor disc membrane]
(Caenorhabditis elegans)
gcy-5 [photoreceptor disc membrane]
(Caenorhabditis elegans)
gcy-13 [photoreceptor disc membrane]
(Caenorhabditis elegans)
GYC [photoreceptor disc membrane]
(Drosophila melanogaster)
CG5719 [photoreceptor disc membrane]
(Drosophila melanogaster)
gcy-27 [photoreceptor disc membrane]
(Caenorhabditis elegans)
gcy-19 [photoreceptor disc membrane]
(Caenorhabditis elegans)
GUCY2F [photoreceptor disc membrane]
(Bos taurus)
GUCY2F [photoreceptor disc membrane]
(Caenorhabditis elegans)
GUCY2F [photoreceptor disc membrane]
(Canis familiaris)
GUCY2F [photoreceptor disc membrane]
(Dictyostelium discoideum)
GUCY2F [photoreceptor disc membrane]
(Drosophila melanogaster)
Gucy2f [photoreceptor disc membrane]
(Mus musculus)
Gucy2f [photoreceptor disc membrane]
(Rattus norvegicus)
Gyc32E [photoreceptor disc membrane]
(Drosophila melanogaster)
gcy-4 [photoreceptor disc membrane]
(Caenorhabditis elegans)
gcy-2 [photoreceptor disc membrane]
(Caenorhabditis elegans)
CG9783 [photoreceptor disc membrane]
(Drosophila melanogaster)
Homologues of GUCY2F [photoreceptor disc membrane]
(Caenorhabditis elegans)
Homologues of GUCY2F [photoreceptor disc membrane]
(Dictyostelium discoideum)
Homologues of GUCY2F [photoreceptor disc membrane]
(Drosophila melanogaster)
gcy-17 [photoreceptor disc membrane]
(Caenorhabditis elegans)
gucy2f [photoreceptor disc membrane]
(Xenopus tropicalis)
gcy-22 [photoreceptor disc membrane]
(Caenorhabditis elegans)
Cross References
RefSeq
NP_001513.2
Guide to Pharmacology - Targets
2899
OpenTargets
ENSG00000101890
GeneCards
P51841
HPA
ENSG00000101890-GUCY2F
Ensembl
ENSG00000101890
,
ENSP00000218006
,
ENST00000218006
PRO
P51841
Pharos - Targets
P51841
HMDB Protein
HMDBP01076
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