Phosphorylation of Cdc25C at Ser 216 by Chk1

Stable Identifier
R-HSA-75010
Type
Reaction [transition]
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
General
SVG |   | PPTX  | SBGN
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

Phosphorylation of Cdc25C at Ser 216 results in both the inhibition of Cdc25C phosphatase activity and the creation of a 14-3-3 docking site (Peng et al. 1997).

Literature References
PubMed ID Title Journal Year
9278512 Mitotic and G2 checkpoint control: regulation of 14-3-3 protein binding by phosphorylation of Cdc25C on serine-216.

Peng, CY, Graves, PR, Thoma, RS, Wu, Z, Shaw, AS, Piwnica-Worms, H

Science 1997
Participants
Participates
Catalyst Activity

protein serine/threonine kinase activity of p-S317,S345-CHEK1 [nucleoplasm]

Orthologous Events
Authored
Created
Cite Us!