There will be a maintenance on OICR IT systems starting Friday Dec 15 at 6PM EST until midnight Sunday Dec 17; Reactome will be affected by this downtime

Service under maintenance from Friday Dec 15 at 6PM EST until midnight Sunday Dec 17

Formation of AT-AC B Complex

Stable Identifier
R-HSA-75081
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

The U4atac/U6atac enters the spliceosome and U6atac snRNA forms base pairing interactions with the 5' ss and also forms base pairing interactions with U12 and U4atac is partially displaced. U5 snRNP, the only snRNP common to both the major and minor splicing pathways, also joins the spliceosome to form the B complex and interacts with nucleotides within the 3' end of the exon flanking the 5' ss (Singh et al.2016, Wu and Krainer 1999).

Participants
Participant Of
Orthologous Events