ATAC spliceosome mediated Lariat formation,5' splice site cleavage

Stable Identifier
R-HSA-75082
Type
Reaction
Species
Homo sapiens
Compartment
nucleoplasm
Locations in the PathwayBrowser
Expand all
Summation

At the beginning of this reaction, 1 molecule of 'ATAC C Complex' is present. At the end of this reaction, 1 molecule of 'ATAC C Complex with lariat containing 5'-end cleaved mRNA' is present.

This reaction takes place in the 'nucleus' (Valadkhan and Manley 2001, Valadkhan et al. 2007).

Literature References
PubMed ID Title Journal Year
11607023 Splicing-related catalysis by protein-free snRNAs

Valadkhan, S, Manley, JL

Nature 2001
17940139 Protein-free spliceosomal snRNAs catalyze a reaction that resembles the first step of splicing

Valadkhan, S, Mohammadi, A, Wachtel, C, Manley, JL

RNA 2007
Participants
Input
Output
Participant Of
hasEvent
Orthologous Events
ATAC spliceosome mediated Lariat formation,5' splice site cleavage (Arabidopsis thaliana)
ATAC spliceosome mediated Lariat formation,5' splice site cleavage (Bos taurus)
ATAC spliceosome mediated Lariat formation,5' splice site cleavage (Caenorhabditis elegans)
ATAC spliceosome mediated Lariat formation,5' splice site cleavage (Canis familiaris)
ATAC spliceosome mediated Lariat formation,5' splice site cleavage (Danio rerio)
ATAC spliceosome mediated Lariat formation,5' splice site cleavage (Drosophila melanogaster)
ATAC spliceosome mediated Lariat formation,5' splice site cleavage (Gallus gallus)
ATAC spliceosome mediated Lariat formation,5' splice site cleavage (Mus musculus)
ATAC spliceosome mediated Lariat formation,5' splice site cleavage (Oryza sativa)
ATAC spliceosome mediated Lariat formation,5' splice site cleavage (Rattus norvegicus)
ATAC spliceosome mediated Lariat formation,5' splice site cleavage (Saccharomyces cerevisiae)
ATAC spliceosome mediated Lariat formation,5' splice site cleavage (Schizosaccharomyces pombe)
ATAC spliceosome mediated Lariat formation,5' splice site cleavage (Sus scrofa)
ATAC spliceosome mediated Lariat formation,5' splice site cleavage (Taeniopygia guttata)
ATAC spliceosome mediated Lariat formation,5' splice site cleavage (Xenopus tropicalis)