ATAC spliceosome mediated Lariat formation,5' splice site cleavage

Stable Identifier
R-HSA-75082
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

At the beginning of this reaction, 1 molecule of 'ATAC C Complex' is present. At the end of this reaction, 1 molecule of 'ATAC C Complex with lariat containing 5'-end cleaved mRNA' is present.

This reaction takes place in the 'nucleus' (Valadkhan and Manley 2001, Valadkhan et al. 2007).

Literature References
PubMed ID Title Journal Year
11607023 Splicing-related catalysis by protein-free snRNAs

Valadkhan, S, Manley, JL

Nature 2001
17940139 Protein-free spliceosomal snRNAs catalyze a reaction that resembles the first step of splicing

Valadkhan, S, Mohammadi, A, Wachtel, C, Manley, JL

RNA 2007
Participants
Participant Of
Orthologous Events