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Fall Back to Closed Pre-initiation Complex
Stable Identifier
R-HSA-75862
Type
Reaction [transition]
Species
Homo sapiens
Compartment
nucleoplasm
ReviewStatus
5/5
Locations in the PathwayBrowser
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Gene expression (Transcription) (Homo sapiens)
RNA Polymerase II Transcription (Homo sapiens)
RNA Polymerase II Pre-transcription Events (Homo sapiens)
Fall Back to Closed Pre-initiation Complex (Homo sapiens)
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The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
At the beginning of this reaction, 1 molecule of 'pol II open pre-initiation complex' is present. At the end of this reaction, 1 molecule of 'pol II closed pre-initiation complex' is present.
This reaction takes place in the 'nucleus'.
Literature References
PubMed ID
Title
Journal
Year
2449431
ATP activates transcription initiation from promoters by RNA polymerase II in a reversible step prior to RNA synthesis.
Conaway, JW
,
Conaway, RC
J Biol Chem
1988
Participants
Input
pol II open pre-initiation complex [nucleoplasm]
(Homo sapiens)
Output
pol II closed pre-initiation complex [nucleoplasm]
(Homo sapiens)
Participates
as an event of
RNA Polymerase II Pre-transcription Events (Homo sapiens)
Orthologous Events
Fall Back to Closed Pre-initiation Complex (Bos taurus)
Fall Back to Closed Pre-initiation Complex (Caenorhabditis elegans)
Fall Back to Closed Pre-initiation Complex (Canis familiaris)
Fall Back to Closed Pre-initiation Complex (Dictyostelium discoideum)
Fall Back to Closed Pre-initiation Complex (Drosophila melanogaster)
Fall Back to Closed Pre-initiation Complex (Gallus gallus)
Fall Back to Closed Pre-initiation Complex (Homo sapiens)
Fall Back to Closed Pre-initiation Complex (Mus musculus)
Fall Back to Closed Pre-initiation Complex (Rattus norvegicus)
Fall Back to Closed Pre-initiation Complex (Saccharomyces cerevisiae)
Fall Back to Closed Pre-initiation Complex (Schizosaccharomyces pombe)
Fall Back to Closed Pre-initiation Complex (Sus scrofa)
Fall Back to Closed Pre-initiation Complex (Xenopus tropicalis)
Created
Timmers, HTM (2003-09-11)
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