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RPS6KA5 [cytosol]
Stable Identifier
R-HSA-772525
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
MSK1
Icon
Locations in the PathwayBrowser
Expand all
Developmental Biology (Homo sapiens)
Nervous system development (Homo sapiens)
Axon guidance (Homo sapiens)
L1CAM interactions (Homo sapiens)
Recycling pathway of L1 (Homo sapiens)
Phosphorylation of L1 by p90rsk (Homo sapiens)
p90rsk [cytosol] (Homo sapiens)
RPS6KA5 [cytosol] (Homo sapiens)
pL1 (S1152):p90rsk:clathrin-dynamin complex [endosome] (Homo sapiens)
p90rsk [cytosol] (Homo sapiens)
RPS6KA5 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:O75582 RPS6KA5
Gene Names
RPS6KA5, MSK1
Chain
chain:1-802
Reference Genes
BioGPS Gene:9252 RPS6KA5
COSMIC (genes):RPS6KA5 RPS6KA5
CTD Gene:9252 RPS6KA5
dbSNP Gene:9252 RPS6KA5
ENSEMBL:ENSG00000100784 RPS6KA5
ENSEMBL_homo_sapiens_GENE:ENSG00000100784.12 RPS6KA5
HGNC:10434 RPS6KA5
KEGG Gene (Homo sapiens):9252 RPS6KA5
Monarch:9252 RPS6KA5
NCBI Gene:9252 RPS6KA5
OMIM:603607 RPS6KA5
UCSC:O75582 RPS6KA5
Reference Transcript
RefSeq:NM_001322235.1 RPS6KA5
RefSeq:NM_182398.2 RPS6KA5
RefSeq:NM_001322237.1 RPS6KA5
RefSeq:NM_004755.3 RPS6KA5
Other Identifiers
11735610_a_at
11735633_a_at
11735634_at
11754447_a_at
1554319_PM_at
1554319_at
1557113_PM_at
1557113_at
16795794
17117636
204633_PM_s_at
204633_s_at
204635_PM_at
204635_at
3076403
3576259
3576261
3576263
3576265
3576267
3576268
3576269
3576271
3576273
3576275
3576277
3576279
3576281
3576283
3576285
3576286
3576287
3576288
3576289
3576291
3576292
3576293
3576294
3576297
3576298
3576299
3576300
3576302
3576303
3576305
3576306
3576307
3576308
3576317
3576320
3576321
3576325
3576327
3576328
3576334
3576335
3576337
3576348
3576349
41432_at
52423_at
7980742
7980744
90417_at
9252
ADDON000244.hg
ADDON001867.hg
A_19_P00322645
A_19_P00812874
A_23_P334795
A_23_P37375
A_24_P237601
A_24_P304636
A_32_P184417
A_32_P88946
A_33_P3305203
A_33_P3316562
GE514359
GE514930
GE54761
GE899607
GO:0000166
GO:0000287
GO:0001818
GO:0003824
GO:0004672
GO:0004674
GO:0004713
GO:0005515
GO:0005524
GO:0005634
GO:0005654
GO:0005737
GO:0006325
GO:0006338
GO:0006351
GO:0006355
GO:0006468
GO:0006954
GO:0007411
GO:0016301
GO:0016310
GO:0016740
GO:0023052
GO:0030154
GO:0032793
GO:0034330
GO:0035175
GO:0035556
GO:0036211
GO:0043226
GO:0043687
GO:0044022
GO:0044024
GO:0045892
GO:0045944
GO:0046872
GO:0048856
GO:0051092
GO:0070498
GO:0099175
GO:0106310
GO:0140096
HMNXSV003015404
HMNXSV003020821
HMNXSV003021193
Hs2.109058.2.S1_3p_at
Hs2.46519.1.S1_3p_at
ILMN_1657515
ILMN_1683097
PH_hs_0003296
PH_hs_0006029
PH_hs_0008840
TC14001434.hg
g3411156_3p_a_at
g4759051_3p_at
p24982
p4640
Participates
as a member of
p90rsk [cytosol] (Homo sapiens)
Other forms of this molecule
RPS6KA5 [nucleoplasm]
p-S212,S360,S376,T581-RPS6KA5 [nucleoplasm]
Cross References
RefSeq
NP_001309166.1
,
NP_872198.1
,
NP_004746.2
,
NP_001309164.1
ZINC - World Drugs
KS6A5_HUMAN
Guide to Pharmacology - Targets
1523
OpenTargets
ENSG00000100784
ZINC - FDA approved
KS6A5_HUMAN
ZINC - Substances
KS6A5_HUMAN
ZINC - Biogenic
KS6A5_HUMAN
ZINC target
O75582
PRO
O75582
PDB
7UP4
,
1VZO
,
3KN6
,
7UP6
,
7UP5
,
7UP8
,
3KN5
,
7UP7
ZINC - Investigational
KS6A5_HUMAN
GeneCards
O75582
HPA
ENSG00000100784-RPS6KA5
Ensembl
ENSP00000479667
,
ENST00000614987
,
ENST00000418736
,
ENSP00000442803
,
ENSP00000402787
,
ENSG00000100784
,
ENST00000536315
Pharos - Targets
O75582
ZINC - Predictions - Purchasable
KS6A5_HUMAN
HMDB Protein
HMDBP01491
Interactors (6)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P67870 CSNK2B
5
CSNK2B [secretory granule lumen]
(R-HSA-6801319)
CSNK2B [extracellular region]
(R-HSA-6806508)
CSNK2B [ficolin-1-rich granule lumen]
(R-HSA-6801290)
CSNK2B [nucleoplasm]
(R-HSA-6805067)
CSNK2B [cytosol]
(R-HSA-201693)
0.659
3
UniProt:Q9NYL2 M3K20
0.602
4
UniProt:Q9UI47-2 CTNNA3
0.556
3
UniProt:Q16539 MAPK14
7
MAPK14 [secretory granule lumen]
(R-HSA-6803300)
MAPK14 [extracellular region]
(R-HSA-6806453)
MAPK14 [ficolin-1-rich granule lumen]
(R-HSA-6803280)
MAPK14 [nucleoplasm]
(R-HSA-446223)
MAPK14 [cytosol]
(R-HSA-428933)
p-T180,Y182-MAPK14 [cytosol]
(R-HSA-428935)
p-T180,Y182-MAPK14 [nucleoplasm]
(R-HSA-446227)
0.547
3
UniProt:Q04206 RELA
7
MeK310-RELA [nucleoplasm]
(R-HSA-8865233)
p-S536-RELA [nucleoplasm]
(R-HSA-9861499)
p-S276,5xAcK-RELA [nucleoplasm]
(R-HSA-5660642)
p-S276-RELA [nucleoplasm]
(R-HSA-5624468)
polySUMO3-K37,K122,K123-RELA [nucleoplasm]
(R-HSA-4755466)
RELA [cytosol]
(R-HSA-168172)
RELA [nucleoplasm]
(R-HSA-177676)
0.536
2
UniProt:Q9Y4C1 KDM3A
1
KDM3A [nucleoplasm]
(R-HSA-3214393)
0.524
3
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