Beta oxidation of myristoyl-CoA to lauroyl-CoA

Stable Identifier
R-HSA-77285
Type
Pathway
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

The second pass through the beta-oxidation spiral starts with the saturated fatty acid myristoyl-CoA (from the first swing through the beta oxidation spiral) and produces lauroyl-CoA. Four enzymatic steps are required starting with LCAD CoA dehydrogenase (Long Chain) activity, followed by three enzymatic steps, enoyl-CoA hydratase, 3-hydroxyacyl-CoA dehydrogenase, and ketoacyl-CoA thiolase activities, all present in the mitochondrial membrane associated trifunctional protein.

Literature References
PubMed ID Title Journal Year
  The Metabolic and Molecular Bases of Inherited Disease, 8th ed   2001
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Participant Of
Event Information
Go Biological Process
Orthologous Events