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POLR3A [nucleoplasm]
Stable Identifier
R-HSA-83700
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
HsRPC1, DNA-directed RNA polymerase III largest subunit , RPC155, RPC1
Locations in the PathwayBrowser
Expand all
Gene expression (Transcription) (Homo sapiens)
RNA Polymerase III Transcription (Homo sapiens)
RNA Polymerase III Abortive And Retractive Initiation (Homo sapiens)
RNA Polymerase III Abortive Initiation At Type 1 Open Promoters (Homo sapiens)
RNA polymerase III:TFIIIB:TFIIIC:TFIIIA:Type 1 Open Promoter Complex [nucleoplasm] (Homo sapiens)
RNA Polymerase III Holoenzyme [nucleoplasm] (Homo sapiens)
POLR3A [nucleoplasm] (Homo sapiens)
RNA Polymerase III Abortive Initiation At Type 2 Open Promoters (Homo sapiens)
RNA Polymerase III:TFIIIB:TFIIIC:Type 2 Open Promoter Complex [nucleoplasm] (Homo sapiens)
RNA Polymerase III Holoenzyme [nucleoplasm] (Homo sapiens)
POLR3A [nucleoplasm] (Homo sapiens)
RNA Polymerase III Abortive Initiation At Type 3 Open Promoters (Homo sapiens)
RNA Polymerase III:TFIIIB:SNAPc:Type 3 Open Promoter Complex [nucleoplasm] (Homo sapiens)
RNA Polymerase III Holoenzyme [nucleoplasm] (Homo sapiens)
POLR3A [nucleoplasm] (Homo sapiens)
RNA Polymerase III Productive Transcription (Homo sapiens)
Elongating RNA Polymerase III Transcription Complex [nucleoplasm] (Homo sapiens)
RNA Polymerase III Holoenzyme [nucleoplasm] (Homo sapiens)
POLR3A [nucleoplasm] (Homo sapiens)
RNA Polymerase III Promoter Opening at Type 1 Promoters (Homo sapiens)
RNA polymerase III:TFIIIB:TFIIIC:TFIIIA:Type 1 Open Promoter Complex [nucleoplasm] (Homo sapiens)
RNA Polymerase III Holoenzyme [nucleoplasm] (Homo sapiens)
POLR3A [nucleoplasm] (Homo sapiens)
RNA polymerase III:TFIIIB:TFIIIC:TFIIIA:Type 1 Promoter Complex [nucleoplasm] (Homo sapiens)
RNA Polymerase III Holoenzyme [nucleoplasm] (Homo sapiens)
POLR3A [nucleoplasm] (Homo sapiens)
RNA Polymerase III Promoter Opening at Type 2 Promoters (Homo sapiens)
RNA Polymerase III:TFIIIB:TFIIIC:Type 2 Open Promoter Complex [nucleoplasm] (Homo sapiens)
RNA Polymerase III Holoenzyme [nucleoplasm] (Homo sapiens)
POLR3A [nucleoplasm] (Homo sapiens)
RNA Polymerase III:TFIIIB:TFIIIC:Type 2 Promoter Complex [nucleoplasm] (Homo sapiens)
RNA Polymerase III Holoenzyme [nucleoplasm] (Homo sapiens)
POLR3A [nucleoplasm] (Homo sapiens)
RNA Polymerase III Promoter Opening at Type 3 Promoters (Homo sapiens)
RNA Polymerase III:TFIIIB:SNAPc:Type 3 Open Promoter Complex [nucleoplasm] (Homo sapiens)
RNA Polymerase III Holoenzyme [nucleoplasm] (Homo sapiens)
POLR3A [nucleoplasm] (Homo sapiens)
RNA Polymerase III:TFIIIB:SNAPc:Type 3 Promoter Complex [nucleoplasm] (Homo sapiens)
RNA Polymerase III Holoenzyme [nucleoplasm] (Homo sapiens)
POLR3A [nucleoplasm] (Homo sapiens)
RNA Polymerase III Retractive RNase Activity at U-tract Pause Sites (Homo sapiens)
Elongating RNA Polymerase III Transcription Complex [nucleoplasm] (Homo sapiens)
RNA Polymerase III Holoenzyme [nucleoplasm] (Homo sapiens)
POLR3A [nucleoplasm] (Homo sapiens)
RNA Polymerase III Simple Start Sequence Initiation At Type 1 Promoters (Homo sapiens)
RNA polymerase III:TFIIIB:TFIIIC:TFIIIA:Type 1 Open Promoter Complex [nucleoplasm] (Homo sapiens)
RNA Polymerase III Holoenzyme [nucleoplasm] (Homo sapiens)
POLR3A [nucleoplasm] (Homo sapiens)
RNA Polymerase III Simple Start Sequence Initiation At Type 2 Promoters (Homo sapiens)
RNA Polymerase III:TFIIIB:TFIIIC:Type 2 Open Promoter Complex [nucleoplasm] (Homo sapiens)
RNA Polymerase III Holoenzyme [nucleoplasm] (Homo sapiens)
POLR3A [nucleoplasm] (Homo sapiens)
RNA Polymerase III Simple Start Sequence Initiation At Type 3 Promoters (Homo sapiens)
RNA Polymerase III:TFIIIB:SNAPc:Type 3 Open Promoter Complex [nucleoplasm] (Homo sapiens)
RNA Polymerase III Holoenzyme [nucleoplasm] (Homo sapiens)
POLR3A [nucleoplasm] (Homo sapiens)
RNA Polymerase III Termination and release of transcribed RNA (Homo sapiens)
Paused RNA Polymerase III Transcription Complex [nucleoplasm] (Homo sapiens)
RNA Polymerase III Holoenzyme [nucleoplasm] (Homo sapiens)
POLR3A [nucleoplasm] (Homo sapiens)
RNA Polymerase III Holoenzyme [nucleoplasm] (Homo sapiens)
POLR3A [nucleoplasm] (Homo sapiens)
RNA Polymerase III Transcriptional Pause at Terminator Sequence (Homo sapiens)
Elongating RNA Polymerase III Transcription Complex [nucleoplasm] (Homo sapiens)
RNA Polymerase III Holoenzyme [nucleoplasm] (Homo sapiens)
POLR3A [nucleoplasm] (Homo sapiens)
Paused RNA Polymerase III Transcription Complex [nucleoplasm] (Homo sapiens)
RNA Polymerase III Holoenzyme [nucleoplasm] (Homo sapiens)
POLR3A [nucleoplasm] (Homo sapiens)
RNA Polymerase III Chain Elongation (Homo sapiens)
Initiation of RNA Polymerase III Productive Transcription (Homo sapiens)
Elongating RNA Polymerase III Transcription Complex [nucleoplasm] (Homo sapiens)
RNA Polymerase III Holoenzyme [nucleoplasm] (Homo sapiens)
POLR3A [nucleoplasm] (Homo sapiens)
RNA Polymerase III Productive Transcription (Homo sapiens)
Elongating RNA Polymerase III Transcription Complex [nucleoplasm] (Homo sapiens)
RNA Polymerase III Holoenzyme [nucleoplasm] (Homo sapiens)
POLR3A [nucleoplasm] (Homo sapiens)
Resumption of RNA Polymerase III Productive Transcription (Homo sapiens)
Elongating RNA Polymerase III Transcription Complex [nucleoplasm] (Homo sapiens)
RNA Polymerase III Holoenzyme [nucleoplasm] (Homo sapiens)
POLR3A [nucleoplasm] (Homo sapiens)
RNA Polymerase III Transcription Initiation (Homo sapiens)
RNA Polymerase III Transcription Initiation From Type 1 Promoter (Homo sapiens)
RNA Polymerase III Promoter Opening at Type 1 Promoters (Homo sapiens)
RNA polymerase III:TFIIIB:TFIIIC:TFIIIA:Type 1 Open Promoter Complex [nucleoplasm] (Homo sapiens)
RNA Polymerase III Holoenzyme [nucleoplasm] (Homo sapiens)
POLR3A [nucleoplasm] (Homo sapiens)
RNA polymerase III:TFIIIB:TFIIIC:TFIIIA:Type 1 Promoter Complex [nucleoplasm] (Homo sapiens)
RNA Polymerase III Holoenzyme [nucleoplasm] (Homo sapiens)
POLR3A [nucleoplasm] (Homo sapiens)
Recruitment of RNA polymerase III to TFIIIB:TFIIIC:TFIIIA:Type 1 Promoter Complex (Homo sapiens)
RNA Polymerase III Holoenzyme [nucleoplasm] (Homo sapiens)
POLR3A [nucleoplasm] (Homo sapiens)
RNA polymerase III:TFIIIB:TFIIIC:TFIIIA:Type 1 Promoter Complex [nucleoplasm] (Homo sapiens)
RNA Polymerase III Holoenzyme [nucleoplasm] (Homo sapiens)
POLR3A [nucleoplasm] (Homo sapiens)
RNA Polymerase III Transcription Initiation From Type 2 Promoter (Homo sapiens)
RNA Polymerase III Promoter Opening at Type 2 Promoters (Homo sapiens)
RNA Polymerase III:TFIIIB:TFIIIC:Type 2 Open Promoter Complex [nucleoplasm] (Homo sapiens)
RNA Polymerase III Holoenzyme [nucleoplasm] (Homo sapiens)
POLR3A [nucleoplasm] (Homo sapiens)
RNA Polymerase III:TFIIIB:TFIIIC:Type 2 Promoter Complex [nucleoplasm] (Homo sapiens)
RNA Polymerase III Holoenzyme [nucleoplasm] (Homo sapiens)
POLR3A [nucleoplasm] (Homo sapiens)
Recruitment of RNA Polymerase III to the TFIIIB:TFIIIC: Type 2 Promoter Complex (Homo sapiens)
RNA Polymerase III Holoenzyme [nucleoplasm] (Homo sapiens)
POLR3A [nucleoplasm] (Homo sapiens)
RNA Polymerase III:TFIIIB:TFIIIC:Type 2 Promoter Complex [nucleoplasm] (Homo sapiens)
RNA Polymerase III Holoenzyme [nucleoplasm] (Homo sapiens)
POLR3A [nucleoplasm] (Homo sapiens)
RNA Polymerase III Transcription Initiation From Type 3 Promoter (Homo sapiens)
RNA Polymerase III Promoter Opening at Type 3 Promoters (Homo sapiens)
RNA Polymerase III:TFIIIB:SNAPc:Type 3 Open Promoter Complex [nucleoplasm] (Homo sapiens)
RNA Polymerase III Holoenzyme [nucleoplasm] (Homo sapiens)
POLR3A [nucleoplasm] (Homo sapiens)
RNA Polymerase III:TFIIIB:SNAPc:Type 3 Promoter Complex [nucleoplasm] (Homo sapiens)
RNA Polymerase III Holoenzyme [nucleoplasm] (Homo sapiens)
POLR3A [nucleoplasm] (Homo sapiens)
Recruitment of RNA Polymerase III to TFIIIB:SNAPc:Type 3 Promoter Complex (Homo sapiens)
RNA Polymerase III Holoenzyme [nucleoplasm] (Homo sapiens)
POLR3A [nucleoplasm] (Homo sapiens)
RNA Polymerase III:TFIIIB:SNAPc:Type 3 Promoter Complex [nucleoplasm] (Homo sapiens)
RNA Polymerase III Holoenzyme [nucleoplasm] (Homo sapiens)
POLR3A [nucleoplasm] (Homo sapiens)
RNA Polymerase III Transcription Termination (Homo sapiens)
RNA Polymerase III Termination and release of transcribed RNA (Homo sapiens)
Paused RNA Polymerase III Transcription Complex [nucleoplasm] (Homo sapiens)
RNA Polymerase III Holoenzyme [nucleoplasm] (Homo sapiens)
POLR3A [nucleoplasm] (Homo sapiens)
RNA Polymerase III Holoenzyme [nucleoplasm] (Homo sapiens)
POLR3A [nucleoplasm] (Homo sapiens)
RNA Polymerase III Transcriptional Pause at Terminator Sequence (Homo sapiens)
Elongating RNA Polymerase III Transcription Complex [nucleoplasm] (Homo sapiens)
RNA Polymerase III Holoenzyme [nucleoplasm] (Homo sapiens)
POLR3A [nucleoplasm] (Homo sapiens)
Paused RNA Polymerase III Transcription Complex [nucleoplasm] (Homo sapiens)
RNA Polymerase III Holoenzyme [nucleoplasm] (Homo sapiens)
POLR3A [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:O14802 POLR3A
Gene Names
POLR3A
Chain
chain:1-1390
Reference Genes
BioGPS Gene:11128 POLR3A
COSMIC (genes):POLR3A POLR3A
CTD Gene:11128 POLR3A
dbSNP Gene:11128 POLR3A
ENSEMBL:ENSG00000148606 POLR3A
ENSEMBL_homo_sapiens_GENE:ENSG00000148606.15 POLR3A
HGNC:30074 POLR3A
KEGG Gene (Homo sapiens):11128 POLR3A
Monarch:11128 POLR3A
NCBI Gene:11128 POLR3A
OMIM:614258 POLR3A
UCSC:O14802 POLR3A
Reference Transcript
RefSeq:NM_007055.3 POLR3A
Other Identifiers
11128
11743086_a_at
11759433_at
16715892
227872_PM_at
227872_at
231763_3p_at
231763_PM_at
231763_at
3296514
3296515
3296516
3296517
3296518
3296519
3296520
3296521
3296522
3296524
3296525
3296526
3296527
3296528
3296529
3296530
3296532
3296534
3296540
3296541
3296542
3296543
3296544
3296545
3296546
3296547
3296548
3296549
3296551
3296552
3296553
3296555
3296556
3296557
3296558
3296559
3296560
3296561
3296563
3296564
47439_at
54384_r_at
62310_at
62311_g_at
77061_at
7934653
A_33_P3322724
GE81719
GE87869
GO:0000428
GO:0001056
GO:0002376
GO:0003677
GO:0003682
GO:0003824
GO:0003899
GO:0005515
GO:0005634
GO:0005654
GO:0005666
GO:0005829
GO:0006351
GO:0006383
GO:0016020
GO:0016740
GO:0016779
GO:0031981
GO:0032728
GO:0034062
GO:0043226
GO:0045087
GO:0046872
GO:0051607
GO:0098542
GO:0140098
HMNXSV003039657
Hs.12035.0.A1_3p_at
Hs.249212.0.S2_3p_x_at
ILMN_1681837
ILMN_2197247
PH_hs_0025542
TC10001446.hg
Participates
as a component of
RNA Polymerase III Holoenzyme [nucleoplasm] (Homo sapiens)
Other forms of this molecule
POLR3A [cytosol]
Inferred To
polr3a [nucleoplasm]
(Xenopus tropicalis)
Polr3A [nucleoplasm]
(Drosophila melanogaster)
POLR3A [nucleoplasm]
(Bos taurus)
POLR3A [nucleoplasm]
(Canis familiaris)
POLR3A [nucleoplasm]
(Dictyostelium discoideum)
POLR3A [nucleoplasm]
(Gallus gallus)
POLR3A [nucleoplasm]
(Saccharomyces cerevisiae)
POLR3A [nucleoplasm]
(Schizosaccharomyces pombe)
POLR3A [nucleoplasm]
(Sus scrofa)
Polr3a [nucleoplasm]
(Mus musculus)
Polr3a [nucleoplasm]
(Rattus norvegicus)
Cross References
RefSeq
NP_008986.2
OpenTargets
ENSG00000148606
HPA
ENSG00000148606-POLR3A
GeneCards
O14802
Ensembl
ENSG00000148606
,
ENST00000372371
,
ENSP00000361446
PRO
O14802
Pharos - Targets
O14802
Orphanet
20641
HMDB Protein
HMDBP09344
PDB
7D59
,
8IUH
,
7DU2
,
8ITY
,
7AEA
,
7AE1
,
7DN3
,
7AE3
,
7A6H
,
7AST
,
7FJI
,
8IUE
,
7FJJ
,
7D58
Interactors (2)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P19388 POLR2E
2
POLR2E [nucleoplasm]
(R-HSA-83713)
POLR2E [cytosol]
(R-HSA-1964438)
0.71
4
UniProt:P62136 PPP1CA
1
PPP1CA [cytosol]
(R-HSA-163525)
0.569
3
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