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POLR2F [nucleoplasm]
Stable Identifier
R-HSA-83714
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
HsRPABC2, DNA-directed RNA polymerase II 14.4 kDa polypeptide (EC 2.7.7.6) (RPB6) (RPB14.4), DNA-directed RNA polymerase II 14.4 kDa polypeptide , RPB6, RPB14.4, RPABC2
Locations in the PathwayBrowser for interactor UniProt:O95402%20MED26
Expand all
Gene expression (Transcription) (Homo sapiens)
RNA Polymerase I Transcription (Homo sapiens)
RNA Polymerase I Promoter Clearance (Homo sapiens)
RNA Polymerase I Transcription Initiation (Homo sapiens)
Assembly of RNA Polymerase I Holoenzyme (human) (Homo sapiens)
POLR2F [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:P61218 POLR2F
Gene Names
POLR2F, POLRF
Chain
initiator methionine:, chain:2-127
Reference Genes
BioGPS Gene:5435 POLR2F
COSMIC (genes):POLR2F POLR2F
CTD Gene:5435 POLR2F
dbSNP Gene:5435 POLR2F
ENSEMBL:ENSG00000100142 POLR2F
ENSEMBL_homo_sapiens_GENE:ENSG00000100142.16 POLR2F
HGNC:9193 POLR2F
KEGG Gene (Homo sapiens):5435 POLR2F
Monarch:5435 POLR2F
NCBI Gene:5435 POLR2F
OMIM:604414 POLR2F
UCSC:P61218 POLR2F
Reference Transcript
RefSeq:NM_021974.4 POLR2F
Other Identifiers
11720324_a_at
11720325_at
209511_PM_at
209511_at
36027_at
3945134
3945136
3945138
3945141
3945143
3945144
3945145
5435
8072979
A_24_P417007
A_33_P3318960
GO:0000428
GO:0001054
GO:0001055
GO:0001056
GO:0001650
GO:0003677
GO:0003824
GO:0003899
GO:0005634
GO:0005654
GO:0005665
GO:0005666
GO:0005730
GO:0005736
GO:0005829
GO:0006351
GO:0006360
GO:0006366
GO:0006399
GO:0016740
GO:0042797
GO:0043226
GO:0140098
HMNXSV003017910
PH_hs_0003285
Z27113_at
g13097770_3p_at
g13097770_3p_x_at
Participates
as a component of
RNA Polymerase III Holoenzyme [nucleoplasm] (Homo sapiens)
RNA Polymerase I Holoenzyme [nucleoplasm] (Homo sapiens)
RNA Polymerase II holoenzyme complex (generic) [nucleoplasm] (Homo sapiens)
RNA Polymerase II holoenzyme complex (p-Ser2,7 CTD) [nucleoplasm] (Homo sapiens)
RNA Polymerase II holoenzyme complex (p-Ser5,7 CTD) [nucleoplasm] (Homo sapiens)
RNA Polymerase II holoenzyme complex (hypophosphorylated):TFIIF complex [nucleoplasm] (Homo sapiens)
RNA Polymerase II holoenzyme complex (phosphorylated) [nucleoplasm] (Homo sapiens)
RNA Polymerase II holoenzyme complex (unphosphorylated) [nucleoplasm] (Homo sapiens)
Ubiquitinated RNA Polymerase II holoenzyme complex (hyperphosphorylated) [nucleoplasm] (Homo sapiens)
RNA Polymerase II holoenzyme complex phosphorylated by CDK12 [nucleoplasm] (Homo sapiens)
RNA Polymerase II holoenzyme complex (hyperphosphorylated) [nucleoplasm] (Homo sapiens)
as an input of
Assembly of RNA Polymerase I Holoenzyme (human) (Homo sapiens)
Other forms of this molecule
POLR2F [cytosol]
Inferred To
polr2f [nucleoplasm]
(Dictyostelium discoideum)
polr2f [nucleoplasm]
(Xenopus tropicalis)
RpII18 [nucleoplasm]
(Drosophila melanogaster)
Ghost homologue of POLR2F [nucleoplasm]
(Canis familiaris)
zgc:92790 [nucleoplasm]
(Danio rerio)
RPO26 [nucleoplasm]
(Saccharomyces cerevisiae)
rpb6 [nucleoplasm]
(Schizosaccharomyces pombe)
rpb-6 [nucleoplasm]
(Caenorhabditis elegans)
RPB6 [nucleoplasm]
(Gallus gallus)
POLR2F [nucleoplasm]
(Bos taurus)
POLR2F [nucleoplasm]
(Plasmodium falciparum)
POLR2F [nucleoplasm]
(Sus scrofa)
Polr2f [nucleoplasm]
(Mus musculus)
Polr2f [nucleoplasm]
(Rattus norvegicus)
Cross References
RefSeq
NP_068809.1
OpenTargets
ENSG00000100142
GeneCards
P61218
HPA
ENSG00000100142-POLR2F
Ensembl
ENST00000442738
,
ENSG00000100142
,
ENSP00000403852
PRO
P61218
Pharos - Targets
P61218
HMDB Protein
HMDBP11912
PDB
7FJJ
,
7D58
,
7FJI
,
8A43
,
7AST
,
5IYA
,
5IYB
,
1QKL
,
5IYC
,
7AE1
,
7A6H
,
8ITY
,
5IYD
,
7DN3
,
7OB9
,
7D59
,
6DRD
,
8IUE
,
7OBB
,
6O9L
,
5IY8
,
5IY6
,
7AE3
,
5IY7
,
7OBA
,
7LBM
,
7VBC
,
7VBB
,
7DU2
,
5IY9
,
7AEA
,
7DTI
,
7DTH
,
7VBA
,
6XRE
,
8IUH
Interactors (3)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P19388 POLR2E
2
POLR2E [nucleoplasm]
(R-HSA-83713)
POLR2E [cytosol]
(R-HSA-1964438)
0.772
6
UniProt:A0JLT2 MED19
1
MED19 [nucleoplasm]
(R-HSA-556819)
0.527
2
UniProt:O95402 MED26
1
MED26 [nucleoplasm]
(R-HSA-556783)
0.527
3
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