NLRP1 oligomerizes

Stable Identifier
R-HSA-844438
Type
Reaction [transition]
Species
Homo sapiens
Compartment
ReviewStatus
5/5
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NLRP1 in the presence of Mg2+ was seen to have altered electrophoretic mobility when MDP was added. This was interpreted as evidence of NLRP1 oligomerization. The extent of oligomerization is unknown.
Literature References
PubMed ID Title Journal Year
17349957 Reconstituted NALP1 inflammasome reveals two-step mechanism of caspase-1 activation

Lartigue, L, Reed, JC, Rouiller, I, Bruey, JM, Faustin, B, Sergienko, E, Volkmann, N, Luciano, F, Bailly-Maitre, B, Hanein, D

Mol Cell 2007
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