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APP(672-713) [extracellular region]
Stable Identifier
R-HSA-879340
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
extracellular region
Synonyms
Beta-amyloid protein 42, Amyloid beta A4 protein, APP, A4_HUMAN
Icon
Locations in the PathwayBrowser
Expand all
Disease (Homo sapiens)
Diseases of programmed cell death (Homo sapiens)
Neurodegenerative Diseases (Homo sapiens)
Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models (Homo sapiens)
APP gene expression (Homo sapiens)
APP(672-713) [extracellular region] (Homo sapiens)
Influx of extracellular calcium (Homo sapiens)
APP(672-713) [extracellular region] (Homo sapiens)
Extracellular matrix organization (Homo sapiens)
ECM proteoglycans (Homo sapiens)
AGRN binds Beta amyloid fibril via GAG chains (Homo sapiens)
AGRN:Beta amyloid fibril [extracellular region] (Homo sapiens)
Beta amyloid fibril [extracellular region] (Homo sapiens)
APP(672-713), APP(672-711) [extracellular region] (Homo sapiens)
APP(672-713) [extracellular region] (Homo sapiens)
Beta amyloid fibril [extracellular region] (Homo sapiens)
APP(672-713), APP(672-711) [extracellular region] (Homo sapiens)
APP(672-713) [extracellular region] (Homo sapiens)
Immune System (Homo sapiens)
Cytokine Signaling in Immune system (Homo sapiens)
Signaling by Interleukins (Homo sapiens)
Interleukin-1 family signaling (Homo sapiens)
Interleukin-1 signaling (Homo sapiens)
TAK1 activates NFkB by phosphorylation and activation of IKKs complex (Homo sapiens)
NFkB complex is transported from cytosol to nucleus (Homo sapiens)
AGER ligands:AGER [plasma membrane] (Homo sapiens)
AGER ligands [extracellular region] (Homo sapiens)
APP(672-713) [extracellular region] (Homo sapiens)
Innate Immune System (Homo sapiens)
Advanced glycosylation endproduct receptor signaling (Homo sapiens)
AGER binds ERK1/2 (Homo sapiens)
AGER ligands:AGER [plasma membrane] (Homo sapiens)
AGER ligands [extracellular region] (Homo sapiens)
APP(672-713) [extracellular region] (Homo sapiens)
AGER ligands:AGER:ERK [plasma membrane] (Homo sapiens)
AGER ligands:AGER [plasma membrane] (Homo sapiens)
AGER ligands [extracellular region] (Homo sapiens)
APP(672-713) [extracellular region] (Homo sapiens)
Advanced glycosylation end product-specific receptor (AGER/RAGE) is a multiligand receptor (Homo sapiens)
AGER ligands [extracellular region] (Homo sapiens)
APP(672-713) [extracellular region] (Homo sapiens)
AGER ligands:AGER [plasma membrane] (Homo sapiens)
AGER ligands [extracellular region] (Homo sapiens)
APP(672-713) [extracellular region] (Homo sapiens)
DDX58/IFIH1-mediated induction of interferon-alpha/beta (Homo sapiens)
TRAF6 mediated NF-kB activation (Homo sapiens)
NFkB complex is transported from cytosol to nucleus (Homo sapiens)
AGER ligands:AGER [plasma membrane] (Homo sapiens)
AGER ligands [extracellular region] (Homo sapiens)
APP(672-713) [extracellular region] (Homo sapiens)
Toll-like Receptor Cascades (Homo sapiens)
Toll Like Receptor 10 (TLR10) Cascade (Homo sapiens)
MyD88 cascade initiated on plasma membrane (Homo sapiens)
TAK1 activates NFkB by phosphorylation and activation of IKKs complex (Homo sapiens)
NFkB complex is transported from cytosol to nucleus (Homo sapiens)
AGER ligands:AGER [plasma membrane] (Homo sapiens)
AGER ligands [extracellular region] (Homo sapiens)
APP(672-713) [extracellular region] (Homo sapiens)
Toll Like Receptor 2 (TLR2) Cascade (Homo sapiens)
Toll Like Receptor TLR1:TLR2 Cascade (Homo sapiens)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Homo sapiens)
TAK1 activates NFkB by phosphorylation and activation of IKKs complex (Homo sapiens)
NFkB complex is transported from cytosol to nucleus (Homo sapiens)
AGER ligands:AGER [plasma membrane] (Homo sapiens)
AGER ligands [extracellular region] (Homo sapiens)
APP(672-713) [extracellular region] (Homo sapiens)
Toll Like Receptor TLR6:TLR2 Cascade (Homo sapiens)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Homo sapiens)
TAK1 activates NFkB by phosphorylation and activation of IKKs complex (Homo sapiens)
NFkB complex is transported from cytosol to nucleus (Homo sapiens)
AGER ligands:AGER [plasma membrane] (Homo sapiens)
AGER ligands [extracellular region] (Homo sapiens)
APP(672-713) [extracellular region] (Homo sapiens)
Toll Like Receptor 3 (TLR3) Cascade (Homo sapiens)
TAK1 activates NFkB by phosphorylation and activation of IKKs complex (Homo sapiens)
NFkB complex is transported from cytosol to nucleus (Homo sapiens)
AGER ligands:AGER [plasma membrane] (Homo sapiens)
AGER ligands [extracellular region] (Homo sapiens)
APP(672-713) [extracellular region] (Homo sapiens)
Toll Like Receptor 4 (TLR4) Cascade (Homo sapiens)
MyD88-independent TLR4 cascade (Homo sapiens)
TRIF(TICAM1)-mediated TLR4 signaling (Homo sapiens)
TAK1 activates NFkB by phosphorylation and activation of IKKs complex (Homo sapiens)
NFkB complex is transported from cytosol to nucleus (Homo sapiens)
AGER ligands:AGER [plasma membrane] (Homo sapiens)
AGER ligands [extracellular region] (Homo sapiens)
APP(672-713) [extracellular region] (Homo sapiens)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Homo sapiens)
TAK1 activates NFkB by phosphorylation and activation of IKKs complex (Homo sapiens)
NFkB complex is transported from cytosol to nucleus (Homo sapiens)
AGER ligands:AGER [plasma membrane] (Homo sapiens)
AGER ligands [extracellular region] (Homo sapiens)
APP(672-713) [extracellular region] (Homo sapiens)
Toll Like Receptor 5 (TLR5) Cascade (Homo sapiens)
MyD88 cascade initiated on plasma membrane (Homo sapiens)
TAK1 activates NFkB by phosphorylation and activation of IKKs complex (Homo sapiens)
NFkB complex is transported from cytosol to nucleus (Homo sapiens)
AGER ligands:AGER [plasma membrane] (Homo sapiens)
AGER ligands [extracellular region] (Homo sapiens)
APP(672-713) [extracellular region] (Homo sapiens)
Toll Like Receptor 7/8 (TLR7/8) Cascade (Homo sapiens)
MyD88 dependent cascade initiated on endosome (Homo sapiens)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Homo sapiens)
TAK1 activates NFkB by phosphorylation and activation of IKKs complex (Homo sapiens)
NFkB complex is transported from cytosol to nucleus (Homo sapiens)
AGER ligands:AGER [plasma membrane] (Homo sapiens)
AGER ligands [extracellular region] (Homo sapiens)
APP(672-713) [extracellular region] (Homo sapiens)
Toll Like Receptor 9 (TLR9) Cascade (Homo sapiens)
MyD88 dependent cascade initiated on endosome (Homo sapiens)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Homo sapiens)
TAK1 activates NFkB by phosphorylation and activation of IKKs complex (Homo sapiens)
NFkB complex is transported from cytosol to nucleus (Homo sapiens)
AGER ligands:AGER [plasma membrane] (Homo sapiens)
AGER ligands [extracellular region] (Homo sapiens)
APP(672-713) [extracellular region] (Homo sapiens)
Metabolism of proteins (Homo sapiens)
Amyloid fiber formation (Homo sapiens)
APP(672-713),APP(672-711) translocate from endosome lumen to extracellular region (Homo sapiens)
APP(672-713), APP(672-711) [extracellular region] (Homo sapiens)
APP(672-713) [extracellular region] (Homo sapiens)
Amyloid fibrils have additional components (Homo sapiens)
Amyloid fibril main peptide chains [extracellular region] (Homo sapiens)
Localized amyloid fibril main peptide chains [extracellular region] (Homo sapiens)
Beta amyloid fibril [extracellular region] (Homo sapiens)
APP(672-713), APP(672-711) [extracellular region] (Homo sapiens)
APP(672-713) [extracellular region] (Homo sapiens)
Amyloid fibrils [plasma membrane] (Homo sapiens)
Amyloid fibril main peptide chains [extracellular region] (Homo sapiens)
Localized amyloid fibril main peptide chains [extracellular region] (Homo sapiens)
Beta amyloid fibril [extracellular region] (Homo sapiens)
APP(672-713), APP(672-711) [extracellular region] (Homo sapiens)
APP(672-713) [extracellular region] (Homo sapiens)
Amyloid precursor proteins form ordered fibrils (Homo sapiens)
Amyloid fibril main peptide chains [extracellular region] (Homo sapiens)
Localized amyloid fibril main peptide chains [extracellular region] (Homo sapiens)
Beta amyloid fibril [extracellular region] (Homo sapiens)
APP(672-713), APP(672-711) [extracellular region] (Homo sapiens)
APP(672-713) [extracellular region] (Homo sapiens)
Amyloid fibril monomers [extracellular region] (Homo sapiens)
Localized amyloid fibril monomers [extracellular region] (Homo sapiens)
APP(672-713), APP(672-711) [extracellular region] (Homo sapiens)
APP(672-713) [extracellular region] (Homo sapiens)
Signal Transduction (Homo sapiens)
Signaling by GPCR (Homo sapiens)
GPCR downstream signalling (Homo sapiens)
G alpha (i) signalling events (Homo sapiens)
Liganded Gi-activating GPCR acts as a GEF for Gi (Homo sapiens)
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
FPR2:FPR2 ligands [plasma membrane] (Homo sapiens)
FPR2 ligands [extracellular region] (Homo sapiens)
APP(672-713) [extracellular region] (Homo sapiens)
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
FPR2:FPR2 ligands [plasma membrane] (Homo sapiens)
FPR2 ligands [extracellular region] (Homo sapiens)
APP(672-713) [extracellular region] (Homo sapiens)
Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
FPR2:FPR2 ligands [plasma membrane] (Homo sapiens)
FPR2 ligands [extracellular region] (Homo sapiens)
APP(672-713) [extracellular region] (Homo sapiens)
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
FPR2:FPR2 ligands [plasma membrane] (Homo sapiens)
FPR2 ligands [extracellular region] (Homo sapiens)
APP(672-713) [extracellular region] (Homo sapiens)
The Ligand:GPCR:Gi complex dissociates (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
FPR2:FPR2 ligands [plasma membrane] (Homo sapiens)
FPR2 ligands [extracellular region] (Homo sapiens)
APP(672-713) [extracellular region] (Homo sapiens)
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
FPR2:FPR2 ligands [plasma membrane] (Homo sapiens)
FPR2 ligands [extracellular region] (Homo sapiens)
APP(672-713) [extracellular region] (Homo sapiens)
G alpha (q) signalling events (Homo sapiens)
Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Homo sapiens)
FPR2:FPR2 ligands [plasma membrane] (Homo sapiens)
FPR2 ligands [extracellular region] (Homo sapiens)
APP(672-713) [extracellular region] (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Homo sapiens)
FPR2:FPR2 ligands [plasma membrane] (Homo sapiens)
FPR2 ligands [extracellular region] (Homo sapiens)
APP(672-713) [extracellular region] (Homo sapiens)
Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Homo sapiens)
FPR2:FPR2 ligands [plasma membrane] (Homo sapiens)
FPR2 ligands [extracellular region] (Homo sapiens)
APP(672-713) [extracellular region] (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Homo sapiens)
FPR2:FPR2 ligands [plasma membrane] (Homo sapiens)
FPR2 ligands [extracellular region] (Homo sapiens)
APP(672-713) [extracellular region] (Homo sapiens)
The Ligand:GPCR:Gq complex dissociates (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Homo sapiens)
FPR2:FPR2 ligands [plasma membrane] (Homo sapiens)
FPR2 ligands [extracellular region] (Homo sapiens)
APP(672-713) [extracellular region] (Homo sapiens)
Ligands of GPCRs that activate Gq/11 [extracellular region] (Homo sapiens)
FPR2 ligands [extracellular region] (Homo sapiens)
APP(672-713) [extracellular region] (Homo sapiens)
GPCR ligand binding (Homo sapiens)
Class A/1 (Rhodopsin-like receptors) (Homo sapiens)
Peptide ligand-binding receptors (Homo sapiens)
Formyl peptide receptors bind formyl peptides and many other ligands (Homo sapiens)
FPR2 binds FPR2 ligands (Homo sapiens)
FPR2 ligands [extracellular region] (Homo sapiens)
APP(672-713) [extracellular region] (Homo sapiens)
FPR2:FPR2 ligands [plasma membrane] (Homo sapiens)
FPR2 ligands [extracellular region] (Homo sapiens)
APP(672-713) [extracellular region] (Homo sapiens)
External Reference Information
External Reference
UniProt:P05067 APP
Gene Names
APP, A4, AD1
Chain
signal peptide:1-17, chain:18-770, chain:18-687, chain:18-671, chain:18-286, chain:672-770, chain:672-713, chain:672-711, chain:688-770, peptide:688-713, peptide:688-711, chain:691-770, chain:712-770, chain:714-770, chain:721-770, chain:740-770
Reference Genes
BioGPS Gene:351 APP
COSMIC (genes):APP APP
CTD Gene:351 APP
dbSNP Gene:351 APP
ENSEMBL:ENSG00000142192 APP
HGNC:620 APP
KEGG Gene (Homo sapiens):351 APP
Monarch:351 APP
NCBI Gene:351 APP
OMIM:104760 APP
UCSC:P05067 APP
Reference Transcript
RefSeq:NM_001136130.2 APP
RefSeq:NM_001136129.2 APP
RefSeq:NM_001204302.1 APP
RefSeq:NM_201414.2 APP
RefSeq:NM_001136016.3 APP
RefSeq:NM_001204301.1 APP
RefSeq:NM_000484.3 APP
RefSeq:NM_001136131.2 APP
RefSeq:NM_001204303.1 APP
RefSeq:NM_201413.2 APP
Other Identifiers
0001230601
11738008_s_at
11741216_x_at
11742210_a_at
11742211_x_at
11742215_s_at
11746866_a_at
11750384_a_at
11751350_a_at
11752199_a_at
11752200_x_at
11752481_a_at
11762804_x_at
16924551
200602_at
211277_3p_x_at
211277_x_at
214953_s_at
351
3927225
3927227
3927228
3927229
3927230
3927233
3927234
3927237
3927241
3927242
3927262
3927264
3927271
3927272
3927273
3927274
3927281
3927282
3927289
3927298
3927300
3927301
3927306
3927307
3927320
3927335
3927336
3927337
41136_s_at
64309_f_at
8069644
A_24_P314159
A_33_P3296479
A_33_P3508822
GE57419
GO:0000003
GO:0000278
GO:0000902
GO:0000978
GO:0001774
GO:0001934
GO:0001967
GO:0002265
GO:0002376
GO:0002576
GO:0003674
GO:0003677
GO:0004867
GO:0005102
GO:0005515
GO:0005575
GO:0005576
GO:0005615
GO:0005622
GO:0005634
GO:0005635
GO:0005641
GO:0005737
GO:0005768
GO:0005769
GO:0005783
GO:0005788
GO:0005790
GO:0005791
GO:0005794
GO:0005796
GO:0005798
GO:0005829
GO:0005856
GO:0005886
GO:0005887
GO:0005905
GO:0005911
GO:0005929
GO:0005975
GO:0006091
GO:0006378
GO:0006397
GO:0006412
GO:0006417
GO:0006464
GO:0006468
GO:0006629
GO:0006810
GO:0006878
GO:0006897
GO:0006915
GO:0006950
GO:0006979
GO:0007049
GO:0007155
GO:0007165
GO:0007176
GO:0007186
GO:0007219
GO:0007267
GO:0007399
GO:0007409
GO:0007568
GO:0007611
GO:0007612
GO:0007617
GO:0007626
GO:0008021
GO:0008088
GO:0008150
GO:0008201
GO:0008203
GO:0008219
GO:0008283
GO:0008285
GO:0008344
GO:0008542
GO:0009056
GO:0009058
GO:0009314
GO:0009986
GO:0009987
GO:0010288
GO:0010466
GO:0010468
GO:0010628
GO:0010629
GO:0010800
GO:0010951
GO:0010952
GO:0010971
GO:0014005
GO:0016020
GO:0016021
GO:0016192
GO:0016199
GO:0016322
GO:0016358
GO:0016504
GO:0019899
GO:0021700
GO:0022607
GO:0030111
GO:0030134
GO:0030154
GO:0030198
GO:0030234
GO:0030414
GO:0030424
GO:0030426
GO:0030546
GO:0030705
GO:0030900
GO:0031093
GO:0031175
GO:0031410
GO:0031594
GO:0031904
GO:0032092
GO:0032588
GO:0032640
GO:0032731
GO:0032755
GO:0032991
GO:0033138
GO:0034330
GO:0034641
GO:0035235
GO:0035253
GO:0040007
GO:0040011
GO:0040014
GO:0042327
GO:0042535
GO:0042592
GO:0042802
GO:0042995
GO:0043005
GO:0043167
GO:0043197
GO:0043198
GO:0043204
GO:0043226
GO:0043235
GO:0043393
GO:0043687
GO:0044267
GO:0044281
GO:0044304
GO:0045080
GO:0045087
GO:0045121
GO:0045177
GO:0045202
GO:0045665
GO:0045821
GO:0045931
GO:0045944
GO:0046330
GO:0046872
GO:0046914
GO:0048143
GO:0048169
GO:0048471
GO:0048669
GO:0048856
GO:0048870
GO:0050730
GO:0050803
GO:0050808
GO:0050877
GO:0050885
GO:0050890
GO:0051091
GO:0051092
GO:0051124
GO:0051233
GO:0051247
GO:0051402
GO:0051425
GO:0051563
GO:0055037
GO:0055085
GO:0070062
GO:0070374
GO:0070555
GO:0070851
GO:0071280
GO:0071287
GO:0071320
GO:0071874
GO:0090647
GO:0097449
GO:0098815
GO:0150003
GO:1900272
GO:1900273
GO:1901224
GO:1902004
GO:1904646
GO:1905606
GO:1905908
GO:1990000
GO:1990090
GO:1990535
GO:1990761
GO:1990812
GO:2000310
GO:2000406
Hs.177486.2.A1_3p_a_at
ILMN_1653283
ILMN_1678152
ILMN_2404063
ILMN_2404065
PH_hs_0010546
TC21000340.hg
TC21000887.hg
Y00264_at
g4502166_3p_at
Participant Of
hasMember
AGER ligands [extracellular region]
APP(672-713), APP(672-711) [extracellular region]
FPR2 ligands [extracellular region]
output
APP gene expression
This entity regulates
Positively
Influx of extracellular calcium
Other forms of this molecule
APP(18-770) [trans-Golgi network membrane]
APP-C99 [cytosol]
APP(18-687) [extracellular region]
APP(688-770) [plasma membrane]
APP(18-770) [Golgi lumen]
APP(18-770) [plasma membrane]
APP(18-671) [endosome lumen]
APP(714-770) [endosome lumen]
APP(712-770) [endosome lumen]
APP(672-770) [endosome lumen]
APP(672-713) [endosome lumen]
APP(672-711) [endosome lumen]
APP(18-770) [endosome lumen]
APP(18-770) [extracellular region]
APP(18-770) [platelet alpha granule lumen]
p-APP [endoplasmic reticulum lumen]
APP [endoplasmic reticulum lumen]
APP(672-711) [extracellular region]
APP(672-711) [cytosol]
Inferred To
App [extracellular region] (Mus musculus)
App [extracellular region] (Rattus norvegicus)
Appl [extracellular region] (Drosophila melanogaster)
app [extracellular region] (Xenopus tropicalis)
appb [extracellular region] (Danio rerio)
apl-1 [extracellular region] (Caenorhabditis elegans)
APP [extracellular region] (Gallus gallus)
Cross References
RefSeq
NP_000475.1
,
NP_958816.1
,
NP_001129603.1
,
NP_001129601.1
,
NP_001191230.1
,
NP_001191232.1
,
NP_001129488.1
,
NP_958817.1
,
NP_001191231.1
,
NP_001129602.1
OpenTargets
ENSG00000142192
ZINC - Substances
A4_HUMAN
ZINC - Biogenic
A4_HUMAN
ZINC target
P05067
PRO
P05067
PDB
3OW9
,
5MYO
,
2OTK
,
5VOS
,
4PWQ
,
3NYL
,
3MXC
,
3U0T
,
2LMN
,
3UMI
,
6OC9
,
5AM8
,
1AAP
,
3UMK
,
4M1C
,
4ONF
,
3DXD
,
1HZ3
,
5VZY
,
3IFO
,
2BP4
,
1ZE7
,
2FK2
,
4MVI
,
5HOW
,
4JFN
,
6OIZ
,
2NAO
,
5LFY
,
4MVK
,
2M9R
,
3IFP
,
2MJ1
,
2FK1
,
3MOQ
,
2MPZ
,
2LMQ
,
3KTM
,
3BAE
,
5ONQ
,
4MDR
,
3BKJ
,
5LV0
,
1MWP
,
2G47
,
3JQL
,
1AML
,
2LNQ
,
3PZZ
,
2M4J
,
1BRC
,
1QXC
,
3L33
,
3GCI
,
3JTI
,
2Y3J
,
2MGT
,
6TI7
,
4XXD
,
5AMB
,
2MVX
,
1QCM
,
4NGE
,
1ZJD
,
5MY4
,
2Y3K
,
6IYC
,
1UOI
,
2LMP
,
5TXD
,
2BEG
,
1TAW
,
2Y2A
,
3NYJ
,
2IPU
,
3UMH
,
2LMO
,
1UOA
,
2FMA
,
3IFL
,
5CSZ
,
5KK3
,
6RHY
,
6ITU
,
1BJC
,
4ONG
,
1BA4
,
5MYX
,
1UO7
,
3IFN
,
2FK3
,
3DXE
,
1Z0Q
,
1UO8
,
1ZE9
,
5C67
,
1QYT
,
5HOX
,
3JQ5
,
2FJZ
,
2LZ3
,
6SHS
,
2WK3
,
2M9S
,
1X11
,
2BOM
,
2Y29
,
5HOY
,
1CA0
,
3OVJ
,
5OQV
,
2LFM
,
3SV1
,
6WXM
,
2R0W
,
5BUO
,
4MVL
,
2MXU
,
5ONP
,
4PQD
,
6CO3
,
2FKL
,
4HIX
,
1BA6
,
3L81
,
1OWT
,
6GFI
,
1TKN
,
4OJF
,
3DXC
,
6O4J
,
2LZ4
,
6TI5
,
1BJB
,
3MXY
,
1IYT
,
2LP1
,
1AMB
,
1AMC
,
6NB9
,
3AYU
,
5AEF
,
1QWP
,
2LOH
,
6TI6
,
2LLM
,
3Q2X
,
5W3P
,
2Y3L
Target Pathogen
5b354852be737e166372e92b
HPA
ENSG00000142192-APP
GeneCards
P05067
Ensembl
ENST00000354192
,
ENSP00000284981
,
ENST00000440126
,
ENSP00000387483
,
ENST00000348990
,
ENSP00000346129
,
ENSG00000142192
,
ENST00000346798
,
ENST00000357903
,
ENSP00000350578
,
ENSP00000351796
,
ENSP00000345463
,
ENST00000358918
Orphanet
15941
ZINC - Predictions - Purchasable
A4_HUMAN
HMDB Protein
HMDBP01991
Interactors (389)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P05067 APP
20
APP-C99 [cytosol]
(R-HSA-9617603)
APP(18-770) [trans-Golgi network membrane]
(R-HSA-5229136)
APP(18-687) [extracellular region]
(R-HSA-9010033)
APP(688-770) [plasma membrane]
(R-HSA-9010028)
APP(18-770) [Golgi lumen]
(R-HSA-8871509)
APP(18-770) [plasma membrane]
(R-HSA-9010038)
APP(18-671) [endosome lumen]
(R-HSA-5693003)
APP(714-770) [endosome lumen]
(R-HSA-6783325)
APP(712-770) [endosome lumen]
(R-HSA-6783331)
APP(672-770) [endosome lumen]
(R-HSA-9010082)
APP(672-713) [endosome lumen]
(R-HSA-5692993)
APP(672-711) [endosome lumen]
(R-HSA-6783333)
APP(18-770) [endosome lumen]
(R-HSA-5229077)
APP(18-770) [extracellular region]
(R-HSA-49335)
APP(18-770) [platelet alpha granule lumen]
(R-HSA-139835)
p-APP [endoplasmic reticulum lumen]
(R-HSA-8957012)
APP [endoplasmic reticulum lumen]
(R-HSA-8956696)
APP(672-711) [extracellular region]
(R-HSA-976740)
APP(672-711) [cytosol]
(R-HSA-877188)
APP(672-713) [extracellular region]
(R-HSA-879340)
0.993
106
UniProt:P56817 BACE1
8
7K-BACE1 [endoplasmic reticulum lumen]
(R-HSA-5693006)
BACE1 [endoplasmic reticulum lumen]
(R-HSA-6783326)
BACE1(22-45) [Golgi-associated vesicle lumen]
(R-HSA-5693069)
7K-BACE1 [Golgi-associated vesicle lumen]
(R-HSA-5693095)
7K-BACE1(46-501) [Golgi-associated vesicle lumen]
(R-HSA-5693106)
BACE1(46-501) [Golgi-associated vesicle lumen]
(R-HSA-5693105)
BACE1(46-501) [plasma membrane]
(R-HSA-5692933)
BACE1 [endosome membrane]
(R-HSA-5692942)
0.869
11
UniProt:O00213 APBB1
1
APBB1 [nucleoplasm]
(R-HSA-5683987)
0.839
7
UniProt:P04156 PRNP
2
PRNP [plasma membrane]
(R-HSA-375060)
PRNP [cytosol]
(R-HSA-9617597)
0.775
6
UniProt:P27797 CALR
6
CALR [integral component of lumenal side of endoplasmic reticulum membrane]
(R-HSA-985502)
CALR [endoplasmic reticulum lumen]
(R-HSA-195905)
CALR [endoplasmic reticulum-Golgi intermediate compartment membrane]
(R-HSA-8863866)
CALR [phagocytic vesicle membrane]
(R-HSA-1236879)
CALR [extracellular region]
(R-HSA-2197641)
CALR [endocytic vesicle lumen]
(R-HSA-2239448)
0.75
5
UniProt:P10636 MAPT
3
MAPT(2-421) [cytosol]
(R-HSA-350628)
MAPT(422-758) [cytosol]
(R-HSA-350642)
MAPT [cytosol]
(R-HSA-201574)
0.749
8
UniProt:Q99714 HSD17B10
1
HSD17B10 [mitochondrial matrix]
(R-HSA-70831)
0.747
7
UniProt:P02647 APOA1
11
Variant apolipoprotein AI [extracellular region]
(R-HSA-976865)
APOA1(25-266) [endocytic vesicle lumen]
(R-HSA-2239460)
APOA1(25-266) [secretory granule lumen]
(R-HSA-350761)
APOA1(25-267) [endoplasmic reticulum lumen]
(R-HSA-174640)
APOA1(19-266) [extracellular region]
(R-HSA-264771)
APOA1(25-266) [plasma membrane]
(R-HSA-216742)
APOA1(25-267) [early endosome]
(R-HSA-2429641)
APOA1(25-267) [cytosol]
(R-HSA-2395781)
APOA1(25-266) [extracellular region]
(R-HSA-174720)
p-APOA1 [endoplasmic reticulum lumen]
(R-HSA-8957081)
APOA1 [endoplasmic reticulum lumen]
(R-HSA-8956724)
0.747
8
UniProt:O95704 APBB3
0.742
5
UniProt:Q9UQF2 JIP1
0.72
5
UniProt:P61812 TGFB2
3
TGFB2 [extracellular region]
(R-HSA-114706)
TGFB2 [platelet alpha granule lumen]
(R-HSA-65938)
TGFB2(20-302) [extracellular region]
(R-HSA-2395269)
0.718
7
UniProt:P09936 UCHL1
1
UCHL1 [cytosol]
(R-HSA-5660679)
0.703
5
UniProt:P30101 PDIA3
3
PDIA3 [recycling endosome membrane]
(R-HSA-8863849)
PDIA3 [phagocytic vesicle]
(R-HSA-1236870)
PDIA3 [endoplasmic reticulum lumen]
(R-HSA-901028)
0.703
6
UniProt:Q92673 SORL1
2
SORL1 [Golgi membrane]
(R-HSA-8871510)
SORL1 [endosome membrane]
(R-HSA-8871475)
0.69
5
UniProt:Q92876 KLK6
0.683
4
UniProt:P37840 SNCA
4
SNCA [extracellular region]
(R-HSA-976954)
SNCA A30P [cytosol]
(R-HSA-5658569)
SNCA [cytosol]
(R-HSA-5658500)
Ub-SNCA [cytosol]
(R-HSA-5660754)
0.675
6
UniProt:Q92529 SHC3
2
p-Y-SHC3 [cytosol]
(R-HSA-3009043)
SHC3 [cytosol]
(R-HSA-3006448)
0.675
5
UniProt:Q9Y287 ITM2B
1
ITM2B(244-266) [extracellular region]
(R-HSA-976878)
0.675
4
UniProt:O14672 ADAM10
6
ADAM10 [plasma membrane]
(R-HSA-157237)
ADAM10(215-824) [plasma membrane]
(R-HSA-179885)
ADAM10 [endoplasmic reticulum lumen]
(R-HSA-8956768)
p-ADAM10 [endoplasmic reticulum lumen]
(R-HSA-8956999)
ADAM10 [tertiary granule membrane]
(R-HSA-6800992)
ADAM10 [specific granule membrane]
(R-HSA-6799566)
0.675
7
UniProt:P42574 CASP3
5
CASP3(176-277) [nucleoplasm]
(R-HSA-211203)
CASP3(29-175) [nucleoplasm]
(R-HSA-211194)
CASP3(1-277) [cytosol]
(R-HSA-57021)
CASP3(29-175) [cytosol]
(R-HSA-141644)
CASP3(176-277) [cytosol]
(R-HSA-141646)
0.675
4
UniProt:P49810 PSEN2
2
PSEN2(298-448) [plasma membrane]
(R-HSA-9013329)
PSEN2(1-297) [plasma membrane]
(R-HSA-201599)
0.675
4
UniProt:P05412 JUN
4
p-S63,S73-JUN [nucleoplasm]
(R-HSA-450237)
JUN [nucleoplasm]
(R-HSA-450250)
JUN [cytosol]
(R-HSA-168194)
p-S63,S73-JUN [cytosol]
(R-HSA-8868682)
0.675
5
UniProt:P02511 CRYAB
1
CRYAB [nucleoplasm]
(R-HSA-6806336)
0.666
7
UniProt:P62937 PPIA
5
PPIA [ficolin-1-rich granule lumen]
(R-HSA-6801391)
PPIA [extracellular exosome]
(R-HSA-6801538)
PPIA [secretory granule lumen]
(R-HSA-6801400)
PPIA [cytosol]
(R-HSA-173123)
PPIA [extracellular region]
(R-HSA-173646)
0.666
4
UniProt:P11142 HSPA8
10
HSPA8 [ficolin-1-rich granule lumen]
(R-HSA-6801494)
Me3K561-HSPA8 [nucleoplasm]
(R-HSA-8932217)
HSPA8 [extracellular region]
(R-HSA-6805936)
HSPA8 [secretory granule lumen]
(R-HSA-6801530)
HSPA8 [nucleoplasm]
(R-HSA-5082380)
HSPA8 [plasma membrane]
(R-HSA-936508)
HSPA8 [clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane]
(R-HSA-888599)
HSPA8 [late endosome lumen]
(R-HSA-9631104)
HSPA8 [lysosomal lumen]
(R-HSA-9625182)
HSPA8 [cytosol]
(R-HSA-264476)
0.666
8
UniProt:P61764 STXBP1
2
STXBP1 [cytosol]
(R-HSA-6794256)
STXBP1 [plasma membrane]
(R-HSA-2980862)
0.666
7
UniProt:P07900 HSP90AA1
8
HSP90AA1 [ficolin-1-rich granule lumen]
(R-HSA-6801470)
HSP90AA1 [endocytic vesicle lumen]
(R-HSA-3221912)
HSP90AA1 [extracellular region]
(R-HSA-3221946)
HSP90AA1 [secretory granule lumen]
(R-HSA-6801515)
HSP90AA1 [plasma membrane]
(R-HSA-534996)
HSP90AA1 [nucleoplasm]
(R-HSA-5082401)
HSP90AA1 [cytosol]
(R-HSA-192864)
HSP90AA1 [lysosomal lumen]
(R-HSA-9622850)
0.666
5
UniProt:P18669 PGAM1
4
PGAM1 [extracellular region]
(R-HSA-6806482)
PGAM1 [ficolin-1-rich granule lumen]
(R-HSA-6803309)
PGAM1 [secretory granule lumen]
(R-HSA-6803293)
PGAM1 [cytosol]
(R-HSA-71442)
0.666
4
UniProt:P07437 TUBB
3
TUBB [azurophil granule lumen]
(R-HSA-6799370)
TUBB [cytosol]
(R-HSA-9020816)
TUBB [extracellular region]
(R-HSA-380317)
0.666
5
UniProt:P60709 ACTB
5
Unfolded ACTB [cytosol]
(R-HSA-390462)
ACTB(1-375) [lysosomal membrane]
(R-HSA-196160)
ACTB(1-375) [cytosol]
(R-HSA-201861)
ACTB(1-375) [nucleoplasm]
(R-HSA-3321990)
ACTB(1-375) [plasma membrane]
(R-HSA-196016)
0.666
8
UniProt:P36544 CHRNA7
1
CHRNA7 [plasma membrane]
(R-HSA-507830)
0.646
4
UniProt:Q02410 APBA1
1
APBA1 [cytosol]
(R-HSA-5336459)
0.646
4
UniProt:Q13526 PIN1
2
PIN1 [nucleoplasm]
(R-HSA-936016)
PIN1 [cytosol]
(R-HSA-9626823)
0.646
4
UniProt:P01137 TGFB1
6
TGFB1 [Golgi lumen]
(R-HSA-177108)
TGFB1 [extracellular region]
(R-HSA-170838)
TGFB1(30-390) [Golgi lumen]
(R-HSA-114705)
TGFB1 [plasma membrane]
(R-HSA-5146781)
TGFB1(30-278) [extracellular region]
(R-HSA-2395367)
TGFB1(30-278) [platelet alpha granule lumen]
(R-HSA-65936)
0.641
3
UniProt:Q92870 APBB2
0.635
3
UniProt:P49768 PSEN1
6
PSEN1(299-467) [azurophil granule membrane]
(R-HSA-6799234)
PSEN1(1-467) [plasma membrane]
(R-HSA-201606)
PSEN1(1-467) [azurophil granule membrane]
(R-HSA-6799235)
PSEN1(1-298) [azurophil granule membrane]
(R-HSA-6799209)
PSEN1(1-298) [plasma membrane]
(R-HSA-2534298)
PSEN1(299-467) [plasma membrane]
(R-HSA-2534245)
0.632
6
UniProt:O35431 Apba2
1
Apba2 [cytosol]
(R-RNO-6794273)
0.618
5
UniProt:P42704 LRPPRC
1
LRPPRC [mitochondrial matrix]
(R-HSA-5336174)
0.612
8
UniProt:Q99767 APBA2
1
APBA2 [cytosol]
(R-HSA-6794245)
0.592
2
UniProt:Q9NP59 SLC40A1
7
SLC40A1 N144H [plasma membrane]
(R-HSA-5655754)
SLC40A1 V162del [plasma membrane]
(R-HSA-5655818)
SLC40A1 D181V [plasma membrane]
(R-HSA-5655786)
SLC40A1 G80V [plasma membrane]
(R-HSA-5655697)
SLC40A1 D157G [plasma membrane]
(R-HSA-5655794)
SLC40A1 A77D [plasma membrane]
(R-HSA-5655698)
SLC40A1 [plasma membrane]
(R-HSA-442390)
0.589
5
UniProt:P29353 SHC1
5
p-Y427-SHC1 [cytosol]
(R-HSA-74684)
SHC1 [cytosol]
(R-HSA-74680)
p-Y349,Y350-SHC1 [cytosol]
(R-HSA-180276)
p-Y-SHC1 [cytosol]
(R-HSA-162568)
p-Y349,Y350,Y427-SHC1 [cytosol]
(R-HSA-912321)
0.589
6
UniProt:Q13625 TP53BP2
1
TP53BP2 [nucleoplasm]
(R-HSA-6799780)
0.581
3
UniProt:O75955 FLOT1
1
FLOT1 [plasma membrane]
(R-HSA-112174)
0.581
5
UniProt:Q99683 MAP3K5
1
MAP3K5 [cytosol]
(R-HSA-167709)
0.564
2
UniProt:P07196 NEFL
1
NEFL [cytosol]
(R-HSA-432284)
0.564
2
UniProt:P08138 NGFR
7
NGFR(29-250) [extracellular region]
(R-HSA-194470)
NGFR [plasma membrane]
(R-HSA-193664)
NGFR(251-427) [plasma membrane]
(R-HSA-194476)
NGFR(273-427) [cytosol]
(R-HSA-194458)
NGFR(251-272) [plasma membrane]
(R-HSA-194509)
NGFR(251-427) [endosome]
(R-HSA-209541)
NGFR(273-427) [nucleoplasm]
(R-HSA-197473)
0.558
2
UniProt:Q16650 TBR1
0.556
3
UniProt:Q02246 CNTN2
1
CNTN2 [plasma membrane]
(R-HSA-373618)
0.556
3
UniProt:Q9NY61 AATF
1
AATF [cytosol]
(R-HSA-205071)
0.556
3
UniProt:P68366 TUBA4A
9
TUBA4A [axonemal microtubule]
(R-HSA-5610443)
TUBA4A [cytosol]
(R-HSA-191694)
TUBA4A [extracellular region]
(R-HSA-350734)
Polyglutamyl-TUBA4A [cytosol]
(R-HSA-8867386)
L-isoglutamyl polyglycyl-TUBA4A [cytosol]
(R-HSA-8867378)
TUBA4A unfolded [cytosol]
(R-HSA-392771)
TUBA4A folding intermediate [cytosol]
(R-HSA-392800)
Ac K40 TUBA4A [axonemal microtubule]
(R-HSA-5624859)
AcK-TUBA4A [cytosol]
(R-HSA-5618318)
0.556
3
UniProt:P14625 HSP90B1
4
HSP90B1 [extracellular region]
(R-HSA-3221653)
HSP90B1 [endocytic vesicle lumen]
(R-HSA-3221623)
p-HSP90B1 [endoplasmic reticulum lumen]
(R-HSA-8957016)
HSP90B1 [endoplasmic reticulum lumen]
(R-HSA-981545)
0.556
3
UniProt:P68363 TUBA1B
9
Ac K40 TUBA1B [axonemal microtubule]
(R-HSA-5624854)
AcK-TUBA1B [cytosol]
(R-HSA-5618285)
TUBA1B folding intermediate [cytosol]
(R-HSA-392797)
TUBA1B unfolded [cytosol]
(R-HSA-392781)
L-isoglutamyl polyglycyl-TUBA1B [cytosol]
(R-HSA-8867436)
Polyglutamyl-TUBA1B [cytosol]
(R-HSA-8867435)
TUBA1B [cytosol]
(R-HSA-191691)
TUBA1B [axonemal microtubule]
(R-HSA-5610434)
TUBA1B(1-450) [cytosol]
(R-HSA-8955581)
0.556
3
UniProt:Q8IU99 CAHM1
0.556
3
UniProt:O75888-3 TNFSF13
0.556
3
UniProt:Q05BL1 Q05BL1
0.556
3
UniProt:Q99719 SEPT5
0.556
3
IntAct:EBI-25936029 EBI11820565
0.556
3
UniProt:Q13393 PLD1
4
PLD1 [tertiary granule membrane]
(R-HSA-6800955)
PLD1 [specific granule membrane]
(R-HSA-6799531)
PLD1 [plasma membrane]
(R-HSA-2028998)
PLD1 [endoplasmic reticulum membrane]
(R-HSA-1498795)
0.556
3
UniProt:Q8WW43 APH1B
2
APH1B [plasma membrane]
(R-HSA-157340)
APH1B [endosome membrane]
(R-HSA-9010060)
0.556
3
UniProt:Q6IPE9 Q6IPE9
0.556
3
UniProt:P14735 IDE
4
PolyUb-IDE [mitochondrial outer membrane]
(R-HSA-6783095)
IDE [mitochondrial outer membrane]
(R-HSA-5696861)
IDE [peroxisomal matrix]
(R-HSA-9033157)
IDE [cytosol]
(R-HSA-9033133)
0.556
3
UniProt:P43405-2 P434052
0.556
3
UniProt:P02766 TTR
2
TTR [azurophil granule lumen]
(R-HSA-6799366)
TTR [extracellular region]
(R-HSA-976883)
0.556
3
UniProt:Q13148 TADBP
0.556
6
IntAct:EBI-25936019 CCSB
0.556
3
UniProt:P19544-6 WT1
0.556
3
UniProt:Q6ZNA4-2 Q6ZNA42
0.556
3
UniProt:P48730 CSNK1D
3
CSNK1D [endoplasmic reticulum-Golgi intermediate compartment membrane]
(R-HSA-5685717)
CSNK1D [nucleoplasm]
(R-HSA-421305)
CSNK1D [cytosol]
(R-HSA-380315)
0.556
3
UniProt:O43236 SEPTIN4
0.556
3
UniProt:O60260-5 PRKN
0.556
5
UniProt:Q96FW1 OTUB1
2
OTUB1 [nucleoplasm]
(R-HSA-6783242)
OTUB1 [cytosol]
(R-HSA-933411)
0.556
3
IntAct:EBI-25880053 IOH23180
0.556
3
UniProt:Q13113 PDZ1I
0.556
3
UniProt:P48736 PIK3CG
1
PIK3CG [cytosol]
(R-HSA-392286)
0.556
3
UniProt:Q16740 CLPP
0.556
3
IntAct:EBI-25936001 CCSB
0.556
3
UniProt:Q6AZY7-2 Q6AZY72
0.556
3
UniProt:P00491 PNP
4
PNP [extracellular region]
(R-HSA-6806505)
PNP [ficolin-1-rich granule lumen]
(R-HSA-6803278)
PNP [secretory granule lumen]
(R-HSA-6803318)
PNP [cytosol]
(R-HSA-61933)
0.556
9
UniProt:Q9UJC3 HOOK1
0.556
3
UniProt:Q9BX74 TM2D1
0.556
3
UniProt:P49711 CTCF
1
CTCF [nucleoplasm]
(R-HSA-3782562)
0.556
3
UniProt:P16234-2 PDGFRA
0.556
3
UniProt:O14939 PLD2
2
PLD2 [endoplasmic reticulum membrane]
(R-HSA-1498791)
PLD2 [plasma membrane]
(R-HSA-2029075)
0.556
3
UniProt:P11277 SPTB
1
SPTB [cytosol]
(R-HSA-391565)
0.556
6
UniProt:Q96S59 RANBP9
1
RANBP9 [cytosol]
(R-HSA-374586)
0.556
3
UniProt:Q14790 CASP8
8
CASP8(1-216) [cytosol]
(R-HSA-933456)
CASP8(375-384) [cytosol]
(R-HSA-933460)
CASP8(1-374) [cytosol]
(R-HSA-3465404)
CASP8(217-374) [mitochondrial outer membrane]
(R-HSA-351869)
CASP8(385-479) [mitochondrial outer membrane]
(R-HSA-351828)
CASP8(1-479) [cytosol]
(R-HSA-57031)
CASP8(385-479) [cytosol]
(R-HSA-76158)
CASP8(217-374) [cytosol]
(R-HSA-75975)
0.556
3
UniProt:Q00266 MAT1A
4
MAT1A V348Gfs*3 [cytosol]
(R-HSA-5603112)
MAT1A H277Afs*75 [cytosol]
(R-HSA-5603099)
MAT1A K181Vfs*5 [cytosol]
(R-HSA-5603077)
MAT1A [cytosol]
(R-HSA-174379)
0.556
3
UniProt:Q06481-5 APLP2
0.556
3
UniProt:P41586-2 ADCYAP1R1
0.556
3
UniProt:Q9GZS3 WDR61
2
WDR61 [nucleoplasm]
(R-HSA-8866696)
WDR61 [cytosol]
(R-HSA-8931534)
0.556
3
UniProt:Q9BS26 ERP44
2
ERP44 [specific granule lumen]
(R-HSA-6799567)
ERP44 [extracellular region]
(R-HSA-6806302)
0.556
3
IntAct:EBI-25934154 EBI16882364
0.556
3
UniProt:O75116 ROCK2
2
Activated ROCK2 [cytosol]
(R-HSA-4687775)
ROCK2 [cytosol]
(R-HSA-419058)
0.556
6
UniProt:P21333-2 FLNA
0.556
3
UniProt:Q00005 2ABB
0.556
3
UniProt:Q92599-3 SEPTIN8
0.556
3
UniProt:Q9Y5Q9 GTF3C3
1
GTF3C3 [nucleoplasm]
(R-HSA-83691)
0.556
3
IntAct:EBI-25857140 ORF
0.556
3
UniProt:Q16828 DUSP6
2
DUSP6 [cytosol]
(R-HSA-5675343)
DUSP6 [nucleoplasm]
(R-HSA-2871619)
0.556
3
UniProt:O14662-5 STX16
0.556
3
UniProt:P60891 PRPS1
1
PRPS1 [cytosol]
(R-HSA-73483)
0.556
3
UniProt:Q8WV41 SNX33
0.556
3
UniProt:O00744 WNT10B
9
N4GlycoAsn-PalmS WNT10B [extracellular exosome]
(R-HSA-3781957)
WNT10B [extracellular region]
(R-HSA-517471)
N4GlycoAsn-PalmS WNT10B [endocytic vesicle membrane]
(R-HSA-3781985)
WNT10B [endoplasmic reticulum lumen]
(R-HSA-3238279)
N4GlycoAsn-WNT10B [endoplasmic reticulum lumen]
(R-HSA-3238220)
N4GlycoAsn-PalmS WNT10B [endoplasmic reticulum lumen]
(R-HSA-3238333)
N4GlycoAsn-PalmS WNT10B [Golgi lumen]
(R-HSA-3247821)
N4GlycoAsn-PalmS WNT10B [extracellular region]
(R-HSA-3247775)
N4GlycoAsn-PalmS WNT10B [plasma membrane]
(R-HSA-3247791)
0.556
3
UniProt:Q8NHT4 Q8NHT4
0.556
3
UniProt:Q9UGJ0-3 Q9UGJ03
0.556
3
UniProt:P04406 GAPDH
1
GAPDH [cytosol]
(R-HSA-70428)
0.556
3
UniProt:P01011 SERPINA3
4
SERPINA3 [azurophil granule lumen]
(R-HSA-6798754)
SERPINA3 [platelet alpha granule lumen]
(R-HSA-8848913)
SERPINA3 [extracellular region]
(R-HSA-6806173)
SERPINA3 [secretory granule lumen]
(R-HSA-6801018)
0.556
3
IntAct:EBI-25834291 CCSB
0.556
3
UniProt:P49755 TMED10
5
TMED10 [endoplasmic reticulum membrane]
(R-HSA-5689479)
TMED10 [ER to Golgi transport vesicle membrane]
(R-HSA-5689843)
TMED10 [endoplasmic reticulum-Golgi intermediate compartment membrane]
(R-HSA-5689845)
TMED10 [transport vesicle]
(R-HSA-6808802)
TMED10 [Golgi membrane]
(R-HSA-6808801)
0.556
3
UniProt:O43680 TCF21
0.556
3
UniProt:P62837 UBE2D2
4
Ub-C85-UBE2D2 [cytosol]
(R-HSA-8864214)
Ub-C85-UBE2D2 [nucleoplasm]
(R-HSA-8864153)
UBE2D2 [nucleoplasm]
(R-HSA-8852067)
UBE2D2 [cytosol]
(R-HSA-934628)
0.556
3
UniProt:Q13564 NAE1
1
NAE1 [cytosol]
(R-HSA-8951449)
0.556
3
UniProt:O14901 KLF11
0.556
3
UniProt:Q13561 DCTN2
1
DCTN2 [cytosol]
(R-HSA-380302)
0.556
3
UniProt:P23142-4 FBLN1
0.556
3
UniProt:P01138 NGF
7
NGF(19-241) [extracellular region]
(R-HSA-187033)
NGF [Golgi lumen]
(R-HSA-166515)
NGF(1-241) [endoplasmic reticulum lumen]
(R-HSA-187026)
NGF(19-241) [Golgi lumen]
(R-HSA-187036)
NGF(19-241) [endoplasmic reticulum lumen]
(R-HSA-187047)
NGF [cytosol]
(R-HSA-190059)
NGF [extracellular region]
(R-HSA-167034)
0.556
9
UniProt:Q92870-2 Q928702
0.556
3
UniProt:P41271-2 NBL1
0.556
3
UniProt:P17612 PRKACA
3
PRKACA [cytosol]
(R-HSA-57844)
PRKACA [ciliary base]
(R-HSA-5610402)
PRKACA [nucleoplasm]
(R-HSA-111936)
0.556
3
UniProt:P22694-8 PRKACB
0.556
3
UniProt:Q8WTV0 SCARB1
0.556
3
UniProt:Q92993-2 KAT5
0.556
3
UniProt:P17980 PSMC3
5
PSMC3 [extracellular region]
(R-HSA-6806496)
PSMC3 [ficolin-1-rich granule lumen]
(R-HSA-6800429)
PSMC3 [secretory granule lumen]
(R-HSA-6800917)
PSMC3 [nucleoplasm]
(R-HSA-174313)
PSMC3 [cytosol]
(R-HSA-68774)
0.556
6
UniProt:Q8N895 ZN366
0.556
3
UniProt:P29466-3 CASP1
0.556
3
UniProt:O60749 SNX2
2
SNX2 [cytoplasmic vesicle membrane]
(R-HSA-434216)
SNX2 [Golgi membrane]
(R-HSA-434333)
0.556
3
UniProt:P12036 NFH
0.556
3
UniProt:Q96AX1 VP33A
0.556
3
UniProt:P61204 ARF3
2
ARF3 [Golgi membrane]
(R-HSA-1604608)
ARF3 [cytosol]
(R-HSA-6807733)
0.556
3
UniProt:P04792 HSPB1
3
p-S15,S78,S82-HSP27 [cytosol]
(R-HSA-5218697)
HSPB1 [cytosol]
(R-HSA-450563)
p-S78,S82 HSPB1 [cytosol]
(R-HSA-5687009)
0.556
3
UniProt:Q3B7T1 EDRF1
0.556
3
UniProt:P28062-2 PSMB8
0.556
3
UniProt:P01034 CST3
6
p-CST3 [endoplasmic reticulum lumen]
(R-HSA-8956911)
CST3 [endoplasmic reticulum lumen]
(R-HSA-8956740)
CST3 [tertiary granule lumen]
(R-HSA-6801370)
CST3 [extracellular region]
(R-HSA-6801534)
CST3 [ficolin-1-rich granule lumen]
(R-HSA-6801383)
Variant cystatin-C [extracellular region]
(R-HSA-976891)
0.556
3
UniProt:P46379-2 BAG6
0.556
5
UniProt:Q15583-2 TGIF1
0.556
3
UniProt:Q92934 BAD
4
p-S99-BAD [cytosol]
(R-HSA-198335)
BAD [cytosol]
(R-HSA-50662)
BAD [mitochondrial outer membrane]
(R-HSA-114242)
p-S128-BAD [cytosol]
(R-HSA-217297)
0.556
3
UniProt:Q13303 KCNAB2
3
KCNAB2 [plasma membrane]
(R-HSA-1297366)
KCNAB2 [specific granule membrane]
(R-HSA-6799627)
KCNAB2 [tertiary granule membrane]
(R-HSA-6800890)
0.556
3
UniProt:Q8NE08 Q8NE08
0.556
3
UniProt:Q01658 DR1
1
DR1 [nucleoplasm]
(R-HSA-3662280)
0.556
3
IntAct:EBI-25911596 CCSB
0.556
3
IntAct:EBI-25939806 RZPDO834E0519D
0.556
3
UniProt:Q8WUB8-2 PHF10
0.556
3
UniProt:P07948 LYN
5
LYN [cytosol]
(R-HSA-354251)
LYN [plasma membrane]
(R-HSA-197943)
p-Y396-LYN [plasma membrane]
(R-HSA-2454229)
MyrG2-PalmC3-LYN [plasma membrane]
(R-HSA-9606875)
p-Y397-LYN [cytosol]
(R-HSA-8942608)
0.556
3
UniProt:P48454 PPP3CC
1
PPP3CC [cytosol]
(R-HSA-61113)
0.556
3
UniProt:P63010-2 AP2B1
0.556
3
UniProt:P16671 CD36
5
CD36 [platelet alpha granule membrane]
(R-HSA-114687)
4xPalmC-CD36 [endocytic vesicle membrane]
(R-HSA-2239449)
4xPalmC-CD36 [specific granule membrane]
(R-HSA-6806151)
CD36 [phagocytic vesicle]
(R-HSA-1236835)
4xPalmC-CD36 [plasma membrane]
(R-HSA-51645)
0.556
3
IntAct:EBI-25830852 RZPDO839G03145
0.556
3
UniProt:Q99547 MPHOSPH6
1
MPHOSPH6 [nucleoplasm]
(R-HSA-6791553)
0.556
3
UniProt:O75604-3 USP2
0.556
3
UniProt:Q13765 NACA
0.556
3
UniProt:Q92915 FGF14
1
FGF14 [cytosol]
(R-HSA-5578837)
0.556
3
UniProt:P21917 DRD4
1
DRD4 [plasma membrane]
(R-HSA-390809)
0.556
6
UniProt:P18509 ADCYAP1
4
ADCYAP1(132-169) [extracellular region]
(R-HSA-420282)
ADCYAP1(2-742) [Golgi membrane]
(R-HSA-187679)
ADCYAP1(82-129) [extracellular region]
(R-HSA-420254)
ADCYAP1(132-158) [extracellular region]
(R-HSA-420144)
0.556
3
UniProt:P17535 JUND
1
JUND [nucleoplasm]
(R-HSA-9009924)
0.556
3
UniProt:P11171-2 EPB41
0.556
3
UniProt:Q9P0L2 MARK1
0.556
3
UniProt:P11171-7 EPB41
0.556
3
UniProt:Q9C026 TRIM9
1
TRIM9 [cytosol]
(R-HSA-976054)
0.556
3
UniProt:O94851 MICA2
0.556
3
UniProt:P10909 CLU
4
CLU(23-449) [platelet alpha granule lumen]
(R-HSA-349733)
CLU(23-449) [extracellular region]
(R-HSA-349732)
CLU(228-449) [extracellular region]
(R-HSA-6810626)
CLU(23-227) [extracellular region]
(R-HSA-6810660)
0.556
3
UniProt:A4FUJ8 A4FUJ8
0.556
3
UniProt:O43852-3 CALU
0.556
3
UniProt:P30519 HMOX2
3
HMOX2 [specific granule membrane]
(R-HSA-6799628)
HMOX2 [plasma membrane]
(R-HSA-6799676)
HMOX2 [endoplasmic reticulum membrane]
(R-HSA-189391)
0.556
3
UniProt:D3DTS7 D3DTS7
0.556
3
UniProt:P48730-2 CSNK1D
0.556
3
UniProt:O14656 TOR1A
1
TOR1A [cytosol]
(R-HSA-8862858)
0.556
3
UniProt:P07602 PSAP
7
PSAP(60-142) [lysosomal lumen]
(R-HSA-351333)
PSAP(60-142) [extracellular region]
(R-HSA-351338)
PSAP(326-340) [extracellular region]
(R-HSA-5336179)
PSAP(?-?) [extracellular region]
(R-HSA-5336190)
PSAP(17-524) [azurophil granule membrane]
(R-HSA-6799212)
PSAP(17-524) [plasma membrane]
(R-HSA-6806262)
PSAP(311-391) [lysosomal membrane]
(R-HSA-1605602)
0.556
3
UniProt:P04216 THY1
2
GPI-THY1 [plasma membrane]
(R-HSA-8940792)
cleaved GPI-THY1 [extracellular region]
(R-HSA-8941025)
0.556
3
UniProt:P42858 HTT
1
HTT [nucleoplasm]
(R-HSA-9023590)
0.556
6
UniProt:Q9UMX0 UBQLN1
1
UBQLN1 [cytosol]
(R-HSA-8866006)
0.556
3
UniProt:Q13867 BLMH
1
BLMH [cytosol]
(R-HSA-983095)
0.556
3
UniProt:P43250-2 GRK6
0.556
3
UniProt:O14645 IDLC
0.556
3
IntAct:EBI-25891095 CCSB
0.556
3
UniProt:P51572 BCAP31
5
BCAP31(165-237) [endoplasmic reticulum membrane]
(R-HSA-351909)
BCAP31(2-245) [endoplasmic reticulum membrane]
(R-HSA-201587)
BCAP31(2-164) [endoplasmic reticulum membrane]
(R-HSA-351826)
BCAP31(238-246) [cytosol]
(R-HSA-351912)
BCAP31 [integral component of lumenal side of endoplasmic reticulum membrane]
(R-HSA-985503)
0.556
3
UniProt:P05556 ITGB1
2
ITGB1 [endosome membrane]
(R-HSA-9611157)
ITGB1 [plasma membrane]
(R-HSA-57596)
0.556
3
UniProt:Q13501 SQSTM1
2
SQSTM1 [cytosol]
(R-HSA-193937)
SQSTM1 [nucleoplasm]
(R-HSA-210961)
0.556
6
UniProt:Q14203-5 DCTN1
0.556
5
UniProt:Q9Y5Z0 BACE2
0.556
3
UniProt:Q00403 GTF2B
1
GTF2B [nucleoplasm]
(R-HSA-65888)
0.556
3
UniProt:O76041 NEBL
0.556
3
UniProt:P01116-2 KRAS
8
pS181-S-Farn-Me KRAS4B [mitochondrial outer membrane]
(R-HSA-9653578)
S-Farn-Me KRAS4B [cytosol]
(R-HSA-9654510)
pro-KRAS4B [cytosol]
(R-HSA-9649686)
S-Farn proKRAS4B [endoplasmic reticulum membrane]
(R-HSA-9649693)
S-Farn KRAS4B [endoplasmic reticulum membrane]
(R-HSA-9649698)
S-Farn-Me KRAS4B [endoplasmic reticulum membrane]
(R-HSA-9649690)
pS181-S-Farn-Me KRAS4B [plasma membrane]
(R-HSA-9653482)
S-Farn-Me KRAS4B [plasma membrane]
(R-HSA-9647815)
0.556
3
UniProt:Q6PK61 Q6PK61
0.556
3
UniProt:P10809 HSPD1
6
HSPD1 [mitochondrial inner membrane]
(R-HSA-1299455)
HSPD1 [mitochondrial matrix]
(R-HSA-1299448)
HSPD1(1-573) [cytosol]
(R-HSA-1267989)
HSPD1(1-573) [mitochondrial inner membrane]
(R-HSA-1299442)
HSPD1(1-26) [mitochondrial matrix]
(R-HSA-8986171)
HSPD1(1-573) [mitochondrial intermembrane space]
(R-HSA-1267963)
0.556
6
UniProt:P31946 YWHAB
1
YWHAB [cytosol]
(R-HSA-48888)
0.556
3
UniProt:P62328 TMSB4X
2
TMSB4X [platelet alpha granule lumen]
(R-HSA-349758)
TMSB4X [extracellular region]
(R-HSA-349753)
0.556
3
UniProt:P61586 RHOA
6
RHOA [ficolin-1-rich granule membrane]
(R-HSA-6804971)
RHOA [secretory granule membrane]
(R-HSA-6804980)
RHOA [endoplasmic reticulum membrane]
(R-HSA-5672082)
RHOA [cytosol]
(R-HSA-194866)
RHOA [cell junction]
(R-HSA-2134503)
RHOA [plasma membrane]
(R-HSA-194510)
0.556
3
UniProt:Q15714-2 TSC22D1
0.556
3
UniProt:Q8TDB4 HUMMR
0.556
3
UniProt:Q00535 CDK5
4
p-Y15-CDK5 [cytosol]
(R-HSA-399809)
CDK5 [nucleoplasm]
(R-HSA-8863586)
CDK5 [cytosol]
(R-HSA-180064)
p-Y15,S159-CDK5 [nucleoplasm]
(R-HSA-6805249)
0.556
3
UniProt:P13051-2 UNG
0.556
3
UniProt:P27824-2 P278242
0.556
3
UniProt:Q99466 NOTCH4
20
p-NICD4 [nucleoplasm]
(R-HSA-9604611)
NICD4 [nucleoplasm]
(R-HSA-157945)
PolyUb-p-NICD4 [nucleoplasm]
(R-HSA-9604624)
NOTCH4(1432-1466) [plasma membrane]
(R-HSA-157635)
NEXT4 [plasma membrane]
(R-HSA-157641)
p-4S-NICD4 [cytosol]
(R-HSA-9604329)
NICD4 [cytosol]
(R-HSA-157636)
Glc,GlcNAc-Fuc-Pre-NOTCH4 [Golgi membrane]
(R-HSA-1911431)
Glc,Gal-GlcNAc-Fuc-Pre-NOTCH4 [Golgi membrane]
(R-HSA-1911422)
Glc,Sia-Gal-GlcNAc-Fuc-Pre-NOTCH4 [Golgi membrane]
(R-HSA-1911507)
FRINGE-modified NOTCH4 Extracellular Fragment (NECD4) [plasma membrane]
(R-HSA-1911521)
FRINGE-modified NOTCH4 Extracellular fragment (NECD4) [Golgi membrane]
(R-HSA-1911523)
Pre-NOTCH4 [endoplasmic reticulum membrane]
(R-HSA-157121)
12xFucT-6xFucS-NOTCH4(24-2003) [endoplasmic reticulum membrane]
(R-HSA-1467340)
12xFucT-8xGlcS-6xFucS-NOTCH4(24-2003) [endoplasmic reticulum membrane]
(R-HSA-1467405)
12xFucT-8xGlcS-6xFucS-NOTCH4(24-2003) [Golgi membrane]
(R-HSA-1472876)
NOTCH4(1337-2003) [plasma membrane]
(R-HSA-157213)
12xFucT-11xGlcS-6xFucS-NOTCH4(24-1336) [extracellular region]
(R-HSA-1983677)
12xFucT-8xGlcS-6xFucS-NOTCH4(24-1336) [Golgi membrane]
(R-HSA-1983674)
NOTCH4(1337-2003) [Golgi membrane]
(R-HSA-157073)
0.556
3
UniProt:A0AVL1 A0AVL1
0.556
3
UniProt:P42773 CDKN2C
1
CDKN2C [cytosol]
(R-HSA-182572)
0.556
3
UniProt:Q96L34 MARK4
1
MARK4 [cytosol]
(R-HSA-5626653)
0.556
3
UniProt:O94985-2 CLSTN1
0.556
3
UniProt:P20340-2 RAB6A
0.556
3
UniProt:P62136 PPP1CA
1
PPP1CA [cytosol]
(R-HSA-163525)
0.556
3
UniProt:Q08722-3 CD47
0.556
3
UniProt:Q02818 NUCB1
2
NUCB1 [endoplasmic reticulum lumen]
(R-HSA-8956751)
p-NUCB1 [endoplasmic reticulum lumen]
(R-HSA-8957027)
0.556
3
IntAct:EBI-25935974 CCSB
0.556
3
UniProt:P16112 ACAN
32
KS(2),CSE-ACAN(393-2415) [extracellular region]
(R-HSA-3791277)
KS(2),C6S-ACAN(393-2415) [extracellular region]
(R-HSA-2533997)
KS(2),C4S-ACAN(393-2415) [extracellular region]
(R-HSA-2533989)
KS(2),CSE-ACAN(17-392) [extracellular region]
(R-HSA-3791335)
KS(2),C4S-ACAN(17-392) [extracellular region]
(R-HSA-3791268)
KS(2),C6S-ACAN(17-392) [extracellular region]
(R-HSA-3791282)
KS(2),C4S-ACAN(376-2415) [extracellular region]
(R-HSA-8855833)
KS(2),CSE-ACAN(376-2415) [extracellular region]
(R-HSA-8855834)
KS(2),C6S-ACAN(376-2415) [extracellular region]
(R-HSA-8855850)
KS(2),C4S-ACAN(17-375) [extracellular region]
(R-HSA-8855840)
KS(2),CSE-ACAN(17-375) [extracellular region]
(R-HSA-8855829)
KS(2),C6S-ACAN(17-375) [extracellular region]
(R-HSA-8855863)
KS(2),CSE-ACAN(17-360) [extracellular region]
(R-HSA-3814818)
KS(2),C4S-ACAN(17-360) [extracellular region]
(R-HSA-3814825)
KS(2),C6S-ACAN(17-360) [extracellular region]
(R-HSA-3814811)
KS(2),CSE-ACAN(361-2415) [extracellular region]
(R-HSA-3814817)
KS(2),C6S-ACAN(361-2415) [extracellular region]
(R-HSA-3814813)
KS(2),C4S-ACAN(361-2415) [extracellular region]
(R-HSA-3814812)
KS(2),C6S-ACAN [extracellular region]
(R-HSA-2318671)
KS(2),C4S-ACAN [extracellular region]
(R-HSA-2318645)
KS(2),CSE-ACAN [extracellular region]
(R-HSA-2318627)
N-glycan ACAN [Golgi lumen]
(R-HSA-2046164)
Keratan(1)-ACAN [Golgi lumen]
(R-HSA-2046214)
KS(2)-ACAN [extracellular region]
(R-HSA-2046287)
KS(2)-ACAN [lysosomal lumen]
(R-HSA-2046195)
ACAN [lysosomal lumen]
(R-HSA-2105015)
KS(1)-ACAN [Golgi lumen]
(R-HSA-2046278)
KS(2)-ACAN [Golgi lumen]
(R-HSA-2046200)
Keratan(4)-ACAN [Golgi lumen]
(R-HSA-2046174)
Keratan(3)-ACAN [Golgi lumen]
(R-HSA-2046207)
Keratan(2)-ACAN [Golgi lumen]
(R-HSA-2046311)
Gal-glycan ACAN [Golgi lumen]
(R-HSA-2046224)
0.556
3
UniProt:Q16363-3 Q163633
0.556
3
UniProt:P32745 SSTR3
2
SSTR3 [plasma membrane]
(R-HSA-374732)
SSTR3 [ciliary membrane]
(R-HSA-5624095)
0.556
3
UniProt:Q8N0S8 Q8N0S8
0.556
3
UniProt:Q8N2W9 PIAS4
2
SUMO1-K35-PIAS4 [nucleoplasm]
(R-HSA-3968415)
PIAS4 [nucleoplasm]
(R-HSA-2993789)
0.556
3
UniProt:Q6P4J0 Q6P4J0
0.556
3
UniProt:P61278 SST
2
SST(89-116) [extracellular region]
(R-HSA-374710)
SST(103-116) [extracellular region]
(R-HSA-374738)
0.556
3
UniProt:Q9Y272 RASD1
0.556
3
UniProt:Q8N594 MPND
0.556
3
IntAct:EBI-25935964 CCSB
0.556
3
UniProt:P61158 ACTR3
1
ACTR3 [cytosol]
(R-HSA-200811)
0.556
3
UniProt:Q99497 PARK7
7
PARK7 [nucleoplasm]
(R-HSA-3900141)
SUMO1-K130-PARK7 [nucleoplasm]
(R-HSA-4085351)
PolyUb-Misfolded PARK7 [late endosome lumen]
(R-HSA-9660005)
Misfolded PARK7 [cytosol]
(R-HSA-9641100)
Ub-Misfolded PARK7 [cytosol]
(R-HSA-9641123)
PolyUb-Misfolded PARK7 [cytosol]
(R-HSA-9641128)
PolyUb-Misfolded PARK7 [lysosomal lumen]
(R-HSA-9659997)
0.556
3
UniProt:P30533 AMRP
0.556
3
UniProt:P19419 ELK1
2
p-4S,T336-ELK1 [nucleoplasm]
(R-HSA-3009350)
ELK1 [nucleoplasm]
(R-HSA-3009346)
0.556
3
UniProt:P0CG47 UBB
109
UBB(1-76) [endocytic vesicle membrane]
(R-HSA-939231)
UBB(77-152) [endocytic vesicle membrane]
(R-HSA-939253)
UBB(153-228) [endocytic vesicle membrane]
(R-HSA-939171)
Ub-33-UBB(1-76) [mitochondrial outer membrane]
(R-HSA-6783023)
Ub-110-UBB(77-152) [mitochondrial outer membrane]
(R-HSA-6783008)
Ub-186-UBB(153-228) [mitochondrial outer membrane]
(R-HSA-6783046)
Ub-215-UBB(153-228) [mitochondrial outer membrane]
(R-HSA-6783002)
Ub-63-UBB(1-76) [mitochondrial outer membrane]
(R-HSA-6783148)
Ub-139-UBB(77-152) [mitochondrial outer membrane]
(R-HSA-6783012)
Ub-158-UBB(153-228) [mitochondrial outer membrane]
(R-HSA-6783162)
Ub-6-UBB(1-76) [mitochondrial outer membrane]
(R-HSA-6783014)
Ub-82-UBB(77-152) [mitochondrial outer membrane]
(R-HSA-6783015)
Ub-163-UBB(153-228) [mitochondrial outer membrane]
(R-HSA-6783025)
Ub-87-UBB(77-152) [mitochondrial outer membrane]
(R-HSA-6782998)
Ub-11-UBB(1-76) [mitochondrial outer membrane]
(R-HSA-6783109)
Ub-124-UBB(77-152) [mitochondrial outer membrane]
(R-HSA-6783131)
Ub-200-UBB(153-228) [mitochondrial outer membrane]
(R-HSA-6783100)
Ub-48-UBB(1-76) [mitochondrial outer membrane]
(R-HSA-6783165)
Ub-182-UBB(153-228) [mitochondrial outer membrane]
(R-HSA-6783160)
Ub-29-UBB(1-76) [mitochondrial outer membrane]
(R-HSA-6783070)
Ub-106-UBB(77-152) [mitochondrial outer membrane]
(R-HSA-6783103)
Ub-27-UBB(1-76) [mitochondrial outer membrane]
(R-HSA-6783038)
Ub-180-UBB(153-228) [mitochondrial outer membrane]
(R-HSA-6783114)
Ub-104-UBB(77-152) [mitochondrial outer membrane]
(R-HSA-6783149)
N6-glycyl-L-lysine-UBB(1-76) [cytosol]
(R-HSA-8869049)
N6-glycyl-L-lysine-UBB(153-228) [cytosol]
(R-HSA-8869046)
N6-glycyl-L-lysine-UBB(77-152) [cytosol]
(R-HSA-8869047)
adenylatedG152-UBB(77-152) [nucleoplasm]
(R-HSA-8852094)
adenylatedG228-UBB(153-228) [nucleoplasm]
(R-HSA-8852104)
adenylatedG76-UBB(1-76) [nucleoplasm]
(R-HSA-8852101)
UBB [cytosol]
(R-HSA-8853516)
adenylatedG76-UBB(1-76) [cytosol]
(R-HSA-8852121)
adenylatedG228-UBB(153-228) [cytosol]
(R-HSA-8852049)
adenylatedG152-UBB(77-152) [cytosol]
(R-HSA-8852113)
Ub-124-UBB(77-152) [endoplasmic reticulum membrane]
(R-HSA-8943100)
Ub-48-UBB(1-76) [endoplasmic reticulum membrane]
(R-HSA-8943138)
Ub-200-UBB(153-228) [endoplasmic reticulum membrane]
(R-HSA-8943117)
UBB(153-228) [plasma membrane]
(R-HSA-3149455)
UBB(1-76) [plasma membrane]
(R-HSA-3149453)
UBB(77-152) [plasma membrane]
(R-HSA-3149463)
UBB(77-152) [endosome membrane]
(R-HSA-939251)
UBB(1-76) [endosome membrane]
(R-HSA-939240)
UBB(153-228) [endosome membrane]
(R-HSA-939247)
UBB(153-228) [endoplasmic reticulum membrane]
(R-HSA-8943098)
UBB(77-152) [endoplasmic reticulum membrane]
(R-HSA-8943111)
UBB(1-76) [endoplasmic reticulum membrane]
(R-HSA-8943078)
Ub-106-UBB(77-152) [cytosol]
(R-HSA-5689191)
Ub-182-UBB(153-228) [cytosol]
(R-HSA-5689214)
Ub-29-UBB(1-76) [cytosol]
(R-HSA-5689207)
Ub-158-UBB(153-228) [cytosol]
(R-HSA-5689099)
Ub-82-UBB(77-152) [cytosol]
(R-HSA-5689080)
Ub-6-UBB(1-76) [cytosol]
(R-HSA-5689075)
Ub-33-UBB(1-76) [cytosol]
(R-HSA-5689198)
Ub-186-UBB(153-228) [cytosol]
(R-HSA-5689146)
Ub-110-UBB(77-152) [cytosol]
(R-HSA-5689203)
Ub-27-UBB(1-76) [cytosol]
(R-HSA-5689161)
Ub-104-UBB(77-152) [cytosol]
(R-HSA-5689139)
Ub-180-UBB(153-228) [cytosol]
(R-HSA-5689138)
Ub-11-UBB(1-76) [cytosol]
(R-HSA-3095929)
Ub-163-UBB(153-228) [cytosol]
(R-HSA-3095932)
Ub-87-UBB(77-152) [cytosol]
(R-HSA-3095917)
Ub-139-UBB(77-152) [endosome membrane]
(R-HSA-939217)
Ub-215-UBB(153-228) [endosome membrane]
(R-HSA-939193)
Ub-63-UBB(1-76) [endosome membrane]
(R-HSA-939167)
Ub-139-UBB(77-152) [plasma membrane]
(R-HSA-939867)
Ub-63-UBB(1-76) [plasma membrane]
(R-HSA-939872)
Ub-215-UBB(153-228) [plasma membrane]
(R-HSA-939852)
Ub-27-UBB(1-76) [nucleoplasm]
(R-HSA-6782673)
Ub-180-UBB(153-228) [nucleoplasm]
(R-HSA-6782604)
Ub-104-UBB(77-152) [nucleoplasm]
(R-HSA-6782627)
Ub-106-UBB(77-152) [nucleoplasm]
(R-HSA-6782652)
Ub-182-UBB(153-228) [nucleoplasm]
(R-HSA-6782665)
Ub-29-UBB(1-76) [nucleoplasm]
(R-HSA-6782595)
Ub-124-UBB(77-152) [nucleoplasm]
(R-HSA-6782527)
Ub-48-UBB(1-76) [nucleoplasm]
(R-HSA-6782505)
Ub-200-UBB(153-228) [nucleoplasm]
(R-HSA-6782478)
Ub-11-UBB(1-76) [nucleoplasm]
(R-HSA-6782649)
Ub-87-UBB(77-152) [nucleoplasm]
(R-HSA-6782607)
Ub-163-UBB(153-228) [nucleoplasm]
(R-HSA-6782598)
Ub-186-UBB(153-228) [nucleoplasm]
(R-HSA-6782655)
Ub-110-UBB(77-152) [nucleoplasm]
(R-HSA-6782591)
Ub-33-UBB(1-76) [nucleoplasm]
(R-HSA-6782601)
UBB(77-152) [nucleoplasm]
(R-HSA-939870)
UBB(1-76) [nucleoplasm]
(R-HSA-939847)
UBB(153-228) [nucleoplasm]
(R-HSA-939854)
Ub-48-UBB(1-76) [nucleoplasm]
(R-HSA-5683040)
Ub-124-UBB(77-152) [nucleoplasm]
(R-HSA-5683036)
Ub-200-UBB(153-228) [nucleoplasm]
(R-HSA-5683038)
Ub-139-UBB(77-152) [nucleoplasm]
(R-HSA-6782488)
Ub-63-UBB(1-76) [nucleoplasm]
(R-HSA-6782489)
Ub-215-UBB(153-228) [nucleoplasm]
(R-HSA-6782475)
Ub-82-UBB(77-152) [nucleoplasm]
(R-HSA-6782683)
Ub-6-UBB(1-76) [nucleoplasm]
(R-HSA-6782600)
Ub-158-UBB(153-228) [nucleoplasm]
(R-HSA-6782639)
UBB(153-228) [late endosome lumen]
(R-HSA-9660014)
UBB(77-152) [late endosome lumen]
(R-HSA-9660021)
UBB(1-76) [late endosome lumen]
(R-HSA-9660017)
Ub-48-UBB(1-76) [cytosol]
(R-HSA-939249)
Ub-124-UBB(77-152) [cytosol]
(R-HSA-939225)
Ub-200-UBB(153-228) [cytosol]
(R-HSA-939197)
UBB(153-228) [cytosol]
(R-HSA-939230)
UBB(77-152) [cytosol]
(R-HSA-939213)
UBB(1-76) [cytosol]
(R-HSA-939214)
UBB(77-152) [lysosomal lumen]
(R-HSA-9660011)
UBB(1-76) [lysosomal lumen]
(R-HSA-9660024)
UBB(153-228) [lysosomal lumen]
(R-HSA-9660025)
Ub-63-UBB(1-76) [cytosol]
(R-HSA-939224)
Ub-215-UBB(153-228) [cytosol]
(R-HSA-939168)
Ub-139-UBB(77-152) [cytosol]
(R-HSA-939235)
0.556
3
UniProt:Q9Y2W7 KCNIP3
1
KCNIP3 [plasma membrane]
(R-HSA-5577044)
0.556
3
UniProt:Q92624 APBP2
0.556
3
UniProt:P29400-2 COL4A5
0.556
3
UniProt:P40227 CCT6A
1
CCT6A [cytosol]
(R-HSA-390454)
0.556
3
UniProt:Q6DN90-2 Q6DN902
0.556
3
UniProt:Q8IWL8 STH
0.556
3
UniProt:Q9ULX5 RN112
0.556
3
UniProt:Q92993 KAT5
1
KAT5 [nucleoplasm]
(R-HSA-3321979)
0.556
3
UniProt:P23560-2 BDNF
0.556
3
IntAct:EBI-25935954 CCSB
0.556
3
UniProt:P49841-2 GSK3B
0.556
3
UniProt:P19404 NDUFV2
1
NDUFV2 [mitochondrial inner membrane]
(R-HSA-163939)
0.556
3
UniProt:P25098 GRK2
4
p-S29-ADRBK1 [plasma membrane]
(R-HSA-111969)
GRK2 [plasma membrane]
(R-HSA-50270)
ADRBK1 [cilium]
(R-HSA-5632504)
p-S29-ADRBK1 [cytosol]
(R-HSA-9645318)
0.556
3
UniProt:Q16082 HSPB2
0.556
3
UniProt:P28482 MAPK1
18
MAPK1 [azurophil granule lumen]
(R-HSA-6799225)
MAPK1 [endoplasmic reticulum lumen]
(R-HSA-9636293)
MAPK1 [extracellular region]
(R-HSA-6806250)
MAPK1 [ficolin-1-rich granule lumen]
(R-HSA-6800964)
p-T185,Y187 MAPK1 E322V [cytosol]
(R-HSA-9652797)
p-T185,Y187 MAPK1 E322K [cytosol]
(R-HSA-9652175)
p-T185,Y187 MAPK1 E81K [cytosol]
(R-HSA-9652799)
p-T185,Y187 MAPK1 S142L [cytosol]
(R-HSA-9652808)
p-T185,Y187 MAPK1 P58L [cytosol]
(R-HSA-9652806)
p-T185,Y187 MAPK1 D321V [cytosol]
(R-HSA-9652791)
p-T185,Y187 MAPK1 D321N [cytosol]
(R-HSA-9652785)
p-T185,Y187 MAPK1 E322A [cytosol]
(R-HSA-9652794)
p-T185,Y187 MAPK1 P58G [cytosol]
(R-HSA-9652802)
p-T185-MAPK1 [cytosol]
(R-HSA-9635773)
MAPK1 [nucleoplasm]
(R-HSA-199960)
p-T185,Y187-MAPK1 [cytosol]
(R-HSA-109853)
MAPK1 [cytosol]
(R-HSA-59282)
p-T185,Y187-MAPK1 [nucleoplasm]
(R-HSA-112354)
0.556
3
UniProt:P09619 PDGFRB
3
PDGFRB [plasma membrane]
(R-HSA-186767)
p-11Y-PDGFRB [plasma membrane]
(R-HSA-8864039)
p-12Y-PDGFRB [plasma membrane]
(R-HSA-186803)
0.556
3
UniProt:P53778 MAPK12
3
MAPK12 [cytosol]
(R-HSA-171025)
MAPK12 [nucleoplasm]
(R-HSA-448833)
p-T183,Y185-MAPK12 [cytosol]
(R-HSA-171021)
0.556
3
UniProt:Q92997 DVL3
4
p-DVL3 [cytosol]
(R-HSA-201680)
pp-DVL3 [cytosol]
(R-HSA-3772400)
DVL3 [cytosol]
(R-HSA-201678)
ub-DVL3 [cytosol]
(R-HSA-4652688)
0.556
3
UniProt:P04049 RAF1
54
p-S338,Y340,Y341-RAF1 [cytosol]
(R-HSA-5624465)
RAF1 [cytosol]
(R-HSA-167205)
p-S338-RAF1 [cytosol]
(R-HSA-5624469)
p-S621-RAF1 S259F [cytosol]
(R-HSA-9656124)
p-S621-RAF1 S257L [cytosol]
(R-HSA-9656121)
p-S621-RAF1 P261L [cytosol]
(R-HSA-9656106)
p-S621-RAF1 N262K [cytosol]
(R-HSA-9656101)
p-S621-RAF1 P261A [cytosol]
(R-HSA-9656103)
p-S621-RAF1 P261S [cytosol]
(R-HSA-9656113)
p-S621-RAF1 S259T [cytosol]
(R-HSA-9656130)
p-S621-RAF1 P261T [cytosol]
(R-HSA-9656115)
p-S621-RAF1 P261R [cytosol]
(R-HSA-9656110)
p-S621-RAF1 S259P [cytosol]
(R-HSA-9656127)
p-S621-RAF1 T260I [cytosol]
(R-HSA-9656136)
p-S621-RAF1 T260R [cytosol]
(R-HSA-9656139)
p-S621-RAF1 V263A [cytosol]
(R-HSA-9656148)
p-S621-RAF1 R256S [cytosol]
(R-HSA-9656119)
p-S621-RAF1 T491I [cytosol]
(R-HSA-9656143)
p-S621-RAF1 D486N [cytosol]
(R-HSA-9656088)
p-S621-RAF1 S427G [cytosol]
(R-HSA-9656134)
p-S621-RAF1 L613V [cytosol]
(R-HSA-9656098)
p-S621-RAF1 G361A [cytosol]
(R-HSA-9656092)
p-S621-RAF1 G370R [cytosol]
(R-HSA-9656094)
p-S621-RAF1 D486G [cytosol]
(R-HSA-9656085)
p-S621-RAF1 T491R [cytosol]
(R-HSA-9656145)
p-S338,Y341,T492,S494,S621 RAF1 D486N [cytosol]
(R-HSA-9656026)
p-S338,Y341,T492,S494,S621 RAF1 S427G [cytosol]
(R-HSA-9656070)
p-S338,Y341,T492,S494,S621 RAF1 L613V [cytosol]
(R-HSA-9656035)
p-S338,Y341,S494,S621-RAF1 T491I [cytosol]
(R-HSA-9656019)
p-S338,Y341,T492,S494,S621 RAF1 G361A [cytosol]
(R-HSA-9656029)
p-S338,Y341,T492,S494,S621 RAF1 G370R [cytosol]
(R-HSA-9656031)
p-S338,Y341,T492,S494,S621 RAF1 D486G [cytosol]
(R-HSA-9656023)
p-S338,Y341,S494,S621 RAF1 T491R [cytosol]
(R-HSA-9656017)
p-S338,Y341,T492,S494,S621 RAF1 S259F [cytosol]
(R-HSA-9656062)
p-S338,Y341,T492,S494,S621 RAF1 P261A [cytosol]
(R-HSA-9656041)
p-S338,Y341,T492,S494,S621 RAF1 S257L [cytosol]
(R-HSA-9656058)
p-S338,Y341,T492,S494,S621 RAF1 P261L [cytosol]
(R-HSA-9656043)
p-S338,Y341,T492,S494,S621 RAF1 P261T [cytosol]
(R-HSA-9656053)
p-S338,Y341,T492,S494,S621 RAF1 N262K [cytosol]
(R-HSA-9656037)
p-S338,Y341,T492,S494,S621 RAF1 P261S [cytosol]
(R-HSA-9656050)
p-S338,Y341,T492,S494,S621 RAF1 S259T [cytosol]
(R-HSA-9656067)
p-S338,Y341,T492,S494,S621 RAF1 T260R [cytosol]
(R-HSA-9656077)
p-S338,Y341,T492,S494,S621 RAF1 P261R [cytosol]
(R-HSA-9656047)
p-S338,Y341,T492,S494,S621 RAF1 R256S [cytosol]
(R-HSA-9656056)
p-S338,Y341,T492,S494,S621 RAF1 T260I [cytosol]
(R-HSA-9656074)
p-S338,Y341,T492,S494,S621 RAF1 V263A [cytosol]
(R-HSA-9656080)
p-S338,Y341,T492,S494,S621 RAF1 S259P [cytosol]
(R-HSA-9656065)
hyperphosphorylated RAF1 [plasma membrane]
(R-HSA-5675193)
p-S621-RAF1 [plasma membrane]
(R-HSA-206222)
p-Y341,T491,S494,S621 RAF1 [plasma membrane]
(R-HSA-5675420)
p-S259,S621-RAF1 [cytosol]
(R-HSA-109786)
p-S621-RAF1 [cytosol]
(R-HSA-206028)
p-S338,Y341,T491,S494,S621 RAF1 [plasma membrane]
(R-HSA-5672665)
p-S338,Y341,T491,S494,S621 RAF1 [cytosol]
(R-HSA-5672664)
0.556
3
UniProt:Q99932-2 SPAG8
0.556
3
UniProt:P04181 OAT
1
PXLP-OAT(26-439) [mitochondrial matrix]
(R-HSA-70638)
0.556
3
UniProt:Q15084 PDIA6
3
p-PDIA6 [endoplasmic reticulum lumen]
(R-HSA-8957031)
PDIA6 [endoplasmic reticulum membrane]
(R-HSA-535530)
PDIA6 [endoplasmic reticulum lumen]
(R-HSA-3009049)
0.556
3
UniProt:P42338 PIK3CB
1
PIK3CB [cytosol]
(R-HSA-74788)
0.556
3
UniProt:P04183 TK1
1
TK1 [cytosol]
(R-HSA-73500)
0.556
3
UniProt:P06241 FYN
6
MyrG2-PalmC3,6-FYN [plasma membrane]
(R-HSA-9606873)
p-S21,Y420-FYN [cytosol]
(R-HSA-5218745)
p-Y531-FYN [cytosol]
(R-HSA-391819)
p-Y420-FYN [cytosol]
(R-HSA-391821)
FYN [cytosol]
(R-HSA-200917)
MyrG-p-Y420-FYN [plasma membrane]
(R-HSA-1810410)
0.556
3
IntAct:EBI-25935944 CCSB
0.556
3
UniProt:P63151 PPP2R2A
2
PPP2R2A [nucleoplasm]
(R-HSA-1564978)
PPP2R2A [cytosol]
(R-HSA-377253)
0.556
3
UniProt:O14494 PLPP1
1
PPAP2A [plasma membrane]
(R-HSA-76106)
0.556
3
UniProt:P23443-4 RPS6KB1
0.556
3
UniProt:P02686-2 MBP
0.556
3
UniProt:Q0P5N6 ARL16
0.556
3
UniProt:P05026 ATP1B1
1
ATP1B1 [plasma membrane]
(R-HSA-375071)
0.556
3
UniProt:P15086 CPB1
1
CPB1 [extracellular region]
(R-HSA-3229247)
0.556