Expression of PPARA

Stable Identifier
R-HSA-879724
Type
Reaction [omitted]
Species
Homo sapiens
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The PPARA gene is transcribed to yield mRNA and the mRNA is translated to yield protein. As inferred from mouse, BMAL1:CLOCK (ARNTL:CLOCK) heterodimers bind E-box elements in the second intron of the PPARA gene and activate transcription of PPARA.

Literature References
PubMed ID Title Journal Year
19710929 Comparative analysis of gene regulation by the transcription factor PPARalpha between mouse and human

Hooiveld, G, Muller, M, Rakhshandehroo, M, Kersten, S

PLoS One 2009
7981125 Human and rat peroxisome proliferator activated receptors (PPARs) demonstrate similar tissue distribution but different responsiveness to PPAR activators

Noonan, D, McDonnell, DP, Jow, L, Mukherjee, R

J Steroid Biochem Mol Biol 1994
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