IDH1 R132L mutant [cytosol]

Stable Identifier
R-HSA-880000
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Synonyms
Isocitrate dehydrogenase (NADP) cytoplasmic R132L
Locations in the PathwayBrowser
External Reference Information
External Reference
Gene Names
IDH1, PICD
Chain
initiator methionine:, chain:2-414
Other Identifiers
11718474_a_at
11718475_s_at
11746174_s_at
1555037_PM_a_at
1555037_a_at
16907758
201193_PM_at
201193_at
2597013
2597014
2597015
2597016
2597019
2597021
2597023
2597029
2597032
2597034
2597036
2597037
2597038
2597040
2597041
2940675
2940678
2940682
3417
39023_at
64372_r_at
8058552
GE54157
GO:0000287
GO:0003824
GO:0004450
GO:0005515
GO:0005576
GO:0005615
GO:0005737
GO:0005739
GO:0005777
GO:0005782
GO:0005829
GO:0005975
GO:0006091
GO:0006097
GO:0006099
GO:0006102
GO:0006103
GO:0006575
GO:0006629
GO:0006739
GO:0006749
GO:0006790
GO:0006979
GO:0008585
GO:0014070
GO:0016491
GO:0016616
GO:0022414
GO:0031410
GO:0034774
GO:0042802
GO:0042803
GO:0043226
GO:0045296
GO:0046872
GO:0048545
GO:0048856
GO:0050661
GO:0051287
GO:0055086
GO:0060696
GO:0070062
GO:0071071
GO:1904724
GO:1904813
HMNXSV003048486
Hs2.11223.2.S1_3p_s_at
ILMN_1696432
ILMN_2091347
PH_hs_0030991
TC02002726.hg
U62389_at
g5174470_3p_at
g5174470_3p_x_at
Participates
Other forms of this molecule
Modified Residues
Name
L-arginine 132 replaced with L-leucine
Coordinate
132
PsiMod
A protein modification that effectively converts a source amino acid residue to an L-leucine.
A protein modification that effectively removes or replaces an L-arginine.
Disease
Name Identifier Synonyms
glioblastoma multiforme DOID:3068 GBM, adult glioblastoma multiforme, grade IV adult Astrocytic tumor, primary glioblastoma multiforme, spongioblastoma multiforme
Cross References
Guide to Pharmacology - Targets
OpenTargets
ZINC - Substances
ZINC target
PRO
COSMIC
IntEnz
GeneCards
Pharos - Targets
ZINC - Predictions - Purchasable
Orphanet
HMDB Protein
Interactors (8)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:P0DP23 CALM1  5 0.65 7
 2-oxoglutarate(2-) [ChEBI:16810]  7 0.623 13
 UniProt:P36957 DLST  4 0.556 3
 UniProt:P37173 TGFBR2  9 0.556 3
 UniProt:P50454 SERPINH1  1 0.556 3
 UniProt:P16284 PECAM1  4 0.556 3
 UniProt:P27797 CALR  6 0.556 3
 UniProt:P17612 PRKACA  4 0.556 3
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