ATP hydrolysis by NSF disassembles the cis-SNARE at the Golgi membrane

Stable Identifier
R-HSA-8847638
Type
Reaction [transition]
Species
Homo sapiens
Compartment
ReviewStatus
5/5
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NSF-mediated ATP hydrolysis promotes disassembly of the cis-SNARE complex, allowing the SNAREs to be reused in subsequent rounds of vesicle fusion (reviewed in Sudhof and Rothman, 2009; Hong and Lev, 2014).
Literature References
PubMed ID Title Journal Year
24119662 Tethering the assembly of SNARE complexes

Hong, W, Lev, S

Trends Cell Biol. 2014
19164740 Membrane fusion: grappling with SNARE and SM proteins

Südhof, TC, Rothman, JE

Science 2009
Participants
Participates
Catalyst Activity

ATP hydrolysis activity of STX5:PalmC-YKT6:BET1L:GOSR1:NSF hexamer:3xSNAPs [Golgi membrane]

Orthologous Events
Authored
Reviewed
Created
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