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PKP4 [cornified envelope]
Stable Identifier
R-HSA-8847721
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cornified envelope
Synonyms
Plakophilin-4, PKP4_HUMAN
Locations in the PathwayBrowser
Expand all
Developmental Biology (Homo sapiens)
Keratinization (Homo sapiens)
Formation of the cornified envelope (Homo sapiens)
Plasma membrane resorption (Homo sapiens)
Mature cornified envelope [cornified envelope] (Homo sapiens)
No FGN-cornified envelope:CDSN [cornified envelope] (Homo sapiens)
No FGN-Cornified envelope [cornified envelope] (Homo sapiens)
No FGN-early cornified envelope [cornified envelope] (Homo sapiens)
Keratin tonofilament:Desmosome network [cornified envelope] (Homo sapiens)
Keratin tonofilament:Desmosome [cornified envelope] (Homo sapiens)
Desmosome [cornified envelope] (Homo sapiens)
Plakophilins [cornified envelope] (Homo sapiens)
PKP4 [cornified envelope] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q99569 PKP4
Gene Names
PKP4
Chain
chain:1-1192
Reference Genes
BioGPS Gene:8502 PKP4
COSMIC (genes):PKP4 PKP4
CTD Gene:8502 PKP4
dbSNP Gene:8502 PKP4
ENSEMBL:ENSG00000144283 PKP4
HGNC:9026 PKP4
KEGG:hsa:8502 PKP4
Monarch:8502 PKP4
NCBI Gene:8502 PKP4
OMIM:604276 PKP4
UCSC:Q99569 PKP4
Reference Transcript
RefSeq:XM_011512016.1 PKP4
RefSeq:NM_001304970.1 PKP4
RefSeq:NM_003628.4 PKP4
RefSeq:NM_001005476.2 PKP4
RefSeq:NM_001304969.1 PKP4
Participates
as a member of
Plakophilins [cornified envelope] (Homo sapiens)
Other forms of this molecule
PKP4 [plasma membrane]
Inferred To
Pkp4 [cornified envelope]
(Mus musculus)
Pkp4 [cornified envelope]
(Rattus norvegicus)
PKP4 [cornified envelope]
(Bos taurus)
PKP4 [cornified envelope]
(Canis familiaris)
PKP4 [cornified envelope]
(Sus scrofa)
Cross References
ENSEMBL
ENST00000389759
,
ENST00000389757
,
ENSP00000374407
,
ENSP00000374409
,
ENSG00000144283
OpenTargets
ENSG00000144283
GeneCards
PKP4
HPA
ENSG00000144283-PKP4
PRO
Q99569
Pharos - Targets
Q99569
GlyGen
Q99569
Interactors (5)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q14160 SCRIB
1
SCRIB [cytosol]
(R-HSA-4608858)
0.684
4
UniProt:Q96RT1 ERBIN
1
ERBIN [plasma membrane]
(R-HSA-1358718)
0.621
4
UniProt:Q12959 DLG1
4
DLG1 [plasma membrane]
(R-HSA-375977)
DLG1 [cytosol]
(R-HSA-416332)
DLG1 [transport vesicle membrane]
(R-HSA-9610631)
DLG1 [endoplasmic reticulum membrane]
(R-HSA-9610593)
0.609
3
UniProt:Q08379 GOLGA2
3
p-S37-GOLGA2 [Golgi membrane]
(R-HSA-2172179)
GOLGA2 [endoplasmic reticulum-Golgi intermediate compartment membrane]
(R-HSA-2167933)
GOLGA2 [Golgi membrane]
(R-HSA-6808764)
0.556
3
UniProt:P35222 CTNNB1
20
CTNNB1 S45A [cytosol]
(R-HSA-9663982)
CTNNB1 S45F [cytosol]
(R-HSA-4791268)
CTNNB1 S45C [cytosol]
(R-HSA-9663983)
CTNNB1 S45Y [cytosol]
(R-HSA-9663975)
CTNNB1 S45N [cytosol]
(R-HSA-9663984)
CTNNB1 S45P [cytosol]
(R-HSA-4791272)
pT41,S45-CTNNB1 S37P [cytosol]
(R-HSA-9663981)
pT41,S45-CTNNB1 S37F [cytosol]
(R-HSA-4839621)
CTNNB1 [nucleoplasm]
(R-HSA-3451168)
CTNNB1 [cytosol]
(R-HSA-448839)
CTNNB1(1-115) [cytosol]
(R-HSA-202930)
CTNNB1(116-376) [cytosol]
(R-HSA-202950)
p-S33,S37,T41,S45 CTNNB1 [cytosol]
(R-HSA-8942374)
p-S37,T41,S45, CTNNB1 [cytosol]
(R-HSA-8942369)
p-T41,S45 CTNNB1 [cytosol]
(R-HSA-8942367)
p-S45 CTNNB1 [cytosol]
(R-HSA-8942363)
CTNNB1 [plasma membrane]
(R-HSA-9038440)
p-S552-CTNNB1 [cytosol]
(R-HSA-3134933)
p-S552-CTNNB1 [nucleoplasm]
(R-HSA-3134926)
p-Y-CTNNB1 [cytosol]
(R-HSA-8876940)
0.491
2
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