Reactome | CYTH proteins stimulate ARF1 GTPase activity

CYTH proteins stimulate ARF1 GTPase activity

Stable Identifier

R-HSA-8847883

Type

Reaction [transition]

Species

Homo sapiens

Compartment

Golgi membrane

ReviewStatus

5/5

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CYTH proteins stimulate ARF1 GTPase activity

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CYTH proteins stimulate the GTPase activity of ARF1, promoting the exchange of GTP for GDP and thereby inactivating ARF1 (Franco et al, 1998; Drin et al, 2008; reviewed in Jackson and Casanova, 2000).

Literature References

PubMed ID	Title	Journal	Year
10652516	Turning on ARF: the Sec7 family of guanine-nucleotide-exchange factors Casanova, JE, Jackson, CL	Trends Cell Biol.	2000
18451304	Asymmetric tethering of flat and curved lipid membranes by a golgin Gounon, P, Morello, V, Drin, G, Casella, JF, Antonny, B	Science	2008
9707577	ARNO3, a Sec7-domain guanine nucleotide exchange factor for ADP ribosylation factor 1, is involved in the control of Golgi structure and function Chardin, P, Robineau, S, Goud, B, Monier, S, Boretto, J, Chavrier, P, Franco, M	Proc. Natl. Acad. Sci. U.S.A.	1998