PTK6 binds PXN

Stable Identifier
R-HSA-8848596
Type
Reaction [binding]
Species
Homo sapiens
Compartment
cytosol
ReviewStatus
5/5
Locations in the PathwayBrowser
Expand all
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
PTK6 binds PXN
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
The SH2 and SH3 domains of PTK6 (BRK) interact with the N-terminal and C-terminal regions of PXN (paxillin) (Chen et al. 2004).
Literature References
PubMed ID Title Journal Year
15572663 Brk activates rac1 and promotes cell migration and invasion by phosphorylating paxillin

Huang, YP, Tsai, YT, Shen, CH, Lin, FC, Chen, HY, Chen, RH

Mol. Cell. Biol. 2004
Participants
Input
Output
Participates
as an event of
Orthologous Events
PTK6 binds PXN (Bos taurus)
PTK6 binds PXN (Danio rerio)
PTK6 binds PXN (Mus musculus)
PTK6 binds PXN (Rattus norvegicus)
PTK6 binds PXN (Sus scrofa)
Authored
Orlic-Milacic, M  (2016-01-05)
Reviewed
Pires, IM  (2016-02-07)
Created
Orlic-Milacic, M  (2015-12-10)
Cite Us!