PolyUb,p-Y700,Y731,Y774-CBL [cytosol]

Stable Identifier
R-HSA-8848826
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser for interactor UniProt:P16333 NCK1
External Reference Information
External Reference
Gene Names
CBL, CBL2, RNF55
Chain
chain:1-906
Reference Transcript
Other Identifiers
0001230102
11724807_at
11724808_at
11724809_at
11724810_at
1568191_at
16732296
206607_at
225231_at
225234_at
229010_at
243475_at
3352072
3352073
3352074
3352075
3352079
3352087
3352088
3352089
3352091
3352092
3352093
3352094
3352095
3352097
3352098
3352102
3352104
3352105
3352106
3352108
3352109
3352110
3352111
3352112
3352113
3352114
3352115
3352116
3352117
3352118
3352129
34416_at
47569_at
51017_at
55605_at
68600_at
7944493
867
A_14_P115221
A_14_P135012
A_14_P135711
A_14_P200324
A_23_P339191
A_23_P53226
A_33_P3256033
GE59823
GE87401
GE88439
GO:0000003
GO:0000209
GO:0001784
GO:0002376
GO:0003674
GO:0004842
GO:0005154
GO:0005509
GO:0005515
GO:0005575
GO:0005622
GO:0005737
GO:0005764
GO:0005773
GO:0005794
GO:0005829
GO:0005886
GO:0005925
GO:0005929
GO:0006464
GO:0006511
GO:0006513
GO:0006810
GO:0006950
GO:0006974
GO:0007165
GO:0007166
GO:0007173
GO:0007175
GO:0007179
GO:0008150
GO:0008219
GO:0008543
GO:0008584
GO:0009056
GO:0010332
GO:0014068
GO:0014823
GO:0016020
GO:0016192
GO:0016567
GO:0016600
GO:0016740
GO:0017124
GO:0019221
GO:0019899
GO:0019901
GO:0023051
GO:0030424
GO:0030426
GO:0030971
GO:0032487
GO:0032991
GO:0033574
GO:0035635
GO:0036120
GO:0036312
GO:0042059
GO:0042594
GO:0042629
GO:0042995
GO:0043066
GO:0043167
GO:0043226
GO:0043303
GO:0044403
GO:0045121
GO:0045296
GO:0045471
GO:0045742
GO:0046677
GO:0046872
GO:0046875
GO:0048260
GO:0048471
GO:0048856
GO:0061024
GO:0061630
GO:0070102
GO:0070997
GO:0071364
GO:0090650
GO:1901215
GO:1990090
GO:1990782
GO:2000583
Hs.196521.0.A1_3p_at
Hs.41324.0.A1_3p_at
Hs.90960.0.A1_3p_at
Hs.90960.0.A2_3p_at
Hs2.423675.1.A1_3p_at
ILMN_1716080
ILMN_2181968
PH_hs_0022112
PH_hs_0031180
TC11001089.hg
TC11002905.hg
X57110_s_at
g4885116_3p_at
Participant Of
Other forms of this molecule
Inferred To
Modified Residues
Name
O4'-phospho-L-tyrosine at 731
Coordinate
731
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 700
Coordinate
700
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 774
Coordinate
774
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
ubiquitinylated lysine (polyubiquitin chain [cytosol]) at unknown position
Modification
polyubiquitin chain [cytosol]
PsiMod Name
PsiMod Definition
A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a ubiquitin.
Cross References
RefSeq
OpenTargets
IntEnz
GeneCards
PRO
Orphanet
HMDB Protein
Interactors (50)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:Q96B97 SH3KBP1  3 0.973 27
 UniProt:P00533 EGFR  59 0.964 26
 UniProt:P62993 GRB2  1 0.961 18
 UniProt:P27986 PIK3R1  15 0.94 16
 UniProt:P46108 CRK  1 0.91 12
 UniProt:P08581 MET  7 0.864 17
 UniProt:O43597 SPRY2  8 0.856 17
 UniProt:P12931 SRC  6 0.845 8
 UniProt:P46109 CRKL  2 0.826 8
 UniProt:P06241 FYN  6 0.798 6
 UniProt:Q9Y5K6 CD2AP  1 0.796 7
 UniProt:P62994 Grb2  3 0.78 5
 UniProt:P29353 SHC1  5 0.77 5
 UniProt:P27348 YWHAQ  1 0.758 6
 UniProt:P06239 LCK  4 0.75 4
 UniProt:P43405 SYK  6 0.743 7
 UniProt:Q15811 ITSN1  1 0.729 12
 UniProt:P07949 RET  2 0.697 8
 UniProt:O14492 SH2B2  2 0.656 7
 UniProt:Q04917 YWHAH  1 0.643 3
 UniProt:P31946 YWHAB  1 0.643 3
 UniProt:O00459 PIK3R2  2 0.621 4
 UniProt:Q9C004 SPY4      0.611 9
 UniProt:P43403 ZAP70  3 0.611 3
 UniProt:P16333 NCK1  2 0.611 3
 UniProt:P62837 UBE2D2  4 0.611 4
 UniProt:P39688 Fyn  6 0.591 3
 UniProt:Q14155 ARHGEF7  1 0.591 9
 UniProt:Q92569 PIK3R3  2 0.57 4
 UniProt:P55085 F2RL1  1 0.556 3
 UniProt:P08487 PLCG1      0.556 3
 UniProt:Q13196 Q13196      0.544 2
 UniProt:P63104 YWHAZ  2 0.527 2
 UniProt:P62258 YWHAE  1 0.527 2
 UniProt:P61981 YWHAG  1 0.527 2
 UniProt:P06240 Lck  5 0.524 2
 UniProt:Q96JA1 LRIG1  2 0.524 2
 UniProt:Q8IZP0-2 ABI1      0.524 3
 UniProt:P08631-2 HCK      0.524 2
 UniProt:F1SDV6 F1SDV6      0.524 2
 UniProt:Q99962 SH3GL2  4 0.499 2
 UniProt:A0A0H3L6J6 A0A0H3L6J6      0.499 3
 UniProt:Q12929 EPS8      0.488 2
 UniProt:P42229 STAT5A  5 0.488 2
 UniProt:P40763 STAT3  10 0.488 2
 UniProt:Q9UKG1 APPL1  1 0.488 2
 UniProt:P46108-2 CRK      0.488 2
 UniProt:P27986-2 PIK3R1      0.488 2
 UniProt:P26450 Pik3r1  4 0.462 2
 UniProt:A9UF07 A9UF07      0.462 4
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