CBL autoubiquitinates

Stable Identifier
R-HSA-8848829
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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PTK6-mediated phosphorylation promotes CBL autoubiquitination, targeting CBL for proteasome mediated degradation (Kang and Lee 2013).

Literature References
PubMed ID Title Journal Year
23352614 PTK6 promotes degradation of c-Cbl through PTK6-mediated phosphorylation

Kang, SA, Lee, ST

Biochem. Biophys. Res. Commun. 2013
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
ubiquitin protein ligase activity of p-Y700,Y731,Y774-CBL [cytosol]
Physical Entity
Activity
Orthologous Events
Authored
Reviewed
Created