Reactome | PTK6 binds KHDRBS1

PTK6 binds KHDRBS1

Stable Identifier

R-HSA-8848939

Type

Reaction

Species

Homo sapiens

Compartment

nucleoplasm

Locations in the PathwayBrowser

Expand all

Summation

PTK6 (BRK) associates with the RNA binding protein KHDRBS1 (SAM68) in the nucleus, where PTK6 and KHDRBS1 colocalize in the SAM68-SLM nuclear bodies (SNBs) (Derry et al. 2000).

Literature References

PubMed ID	Title	Journal	Year
10913193	Sik (BRK) phosphorylates Sam68 in the nucleus and negatively regulates its RNA binding ability	Mol. Cell. Biol.	2000

Participants

Input

KHDRBS1 [nucleoplasm] (Homo sapiens)
p-Y342-PTK6 [nucleoplasm] (Homo sapiens)

Output

p-Y342-PTK6:KHDRBS1 [nucleoplasm] (Homo sapiens)

Participant Of

hasEvent

PTK6 Regulates Proteins Involved in RNA Processing

Orthologous Events

PTK6 binds KHDRBS1 (Bos taurus)

PTK6 binds KHDRBS1 (Danio rerio)

PTK6 binds KHDRBS1 (Mus musculus)

PTK6 binds KHDRBS1 (Rattus norvegicus)

PTK6 binds KHDRBS1 (Sus scrofa)

PTK6 binds KHDRBS1 (Xenopus tropicalis)

Authored

Orlic-Milacic, Marija, 2016-01-04

Reviewed

Pires, Isabel M, 2016-02-07