PTK6 binds KHDRBS1

Stable Identifier
R-HSA-8848939
Type
Reaction [binding]
Species
Homo sapiens
Compartment
nucleoplasm
Locations in the PathwayBrowser
Expand all
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
PTK6 binds KHDRBS1
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

PTK6 (BRK) associates with the RNA binding protein KHDRBS1 (SAM68) in the nucleus, where PTK6 and KHDRBS1 colocalize in the SAM68-SLM nuclear bodies (SNBs) (Derry et al. 2000).

Literature References
PubMed ID Title Journal Year
10913193 Sik (BRK) phosphorylates Sam68 in the nucleus and negatively regulates its RNA binding ability

Derry, JJ, Richard, S, Valderrama Carvajal, H, Ye, X, Vasioukhin, V, Cochrane, AW, Chen, T, Tyner, AL

Mol. Cell. Biol. 2000
Participants
Input
Output
Participant Of
hasEvent
Orthologous Events
PTK6 binds KHDRBS1 (Bos taurus)
PTK6 binds KHDRBS1 (Caenorhabditis elegans)
PTK6 binds KHDRBS1 (Danio rerio)
PTK6 binds KHDRBS1 (Mus musculus)
PTK6 binds KHDRBS1 (Rattus norvegicus)
PTK6 binds KHDRBS1 (Sus scrofa)
PTK6 binds KHDRBS1 (Xenopus tropicalis)
Authored
Orlic-Milacic, M  (2016-01-05)
Reviewed
Pires, IM  (2016-02-07)
Created
Orlic-Milacic, M  (2015-12-11)