Reactome | PTK6 binds KHDRBS1

PTK6 binds KHDRBS1

Stable Identifier

R-HSA-8848939

Type

Reaction [binding]

Species

Homo sapiens

Compartment

nucleoplasm

Locations in the PathwayBrowser

Expand all

General

SBML | | PDF

SVG | | PPTX | SBGN

Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

PTK6 (BRK) associates with the RNA binding protein KHDRBS1 (SAM68) in the nucleus, where PTK6 and KHDRBS1 colocalize in the SAM68-SLM nuclear bodies (SNBs) (Derry et al. 2000).

Literature References

PubMed ID	Title	Journal	Year
10913193	Sik (BRK) phosphorylates Sam68 in the nucleus and negatively regulates its RNA binding ability Derry, JJ, Richard, S, Valderrama Carvajal, H, Ye, X, Vasioukhin, V, Cochrane, AW, Chen, T, Tyner, AL	Mol. Cell. Biol.	2000