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PTK6 phosphorylates KHDRBS2

Stable Identifier
R-HSA-8849032
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

Nuclear PTK6 (BRK) phosphorylates the RNA binding protein KHDRSB2 (SLM1) on an unknown tyrosine residue, thus inhibiting its interaction with RNA. KDRSB2 is a SAM68 (KHDRSB1) family member whose function has been poorly studied (Haegebarth et al. 2004).

Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
protein tyrosine kinase activity of p-Y342-PTK6 [nucleoplasm]
Physical Entity
Activity
Orthologous Events