Reactome: A Curated Pathway Database

PTK6 phosphorylates KHDRBS2

Stable Identifier
R-HSA-8849032
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

Nuclear PTK6 (BRK) phosphorylates the RNA binding protein KHDRSB2 (SLM1) on an unknown tyrosine residue, thus inhibiting its interaction with RNA. KDRSB2 is a SAM68 (KHDRSB1) family member whose function has been poorly studied (Haegebarth et al. 2004).

Literature References
Participants
Participant Of
This entity is regulated by:
Title Physical Entity Activity
protein tyrosine kinase activity of p-Y342-PTK6 [nucleoplasm] p-Y342-PTK6 [nucleoplasm] protein tyrosine kinase activity (0004713)
Orthologous Events